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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none HO O HO Cholesterol From Cholersterol Biosynthesis Progesterone Signaling Steroid Hormone Pregnenolone 17-a-OH-Pregnenolone HO =O CH OH 17-a-OH-Progesterone To Androgen Synthesis and Metabolism 11-Deoxycorticosterone C =O CH C =O CH C O =O CH C 3 3 3 2 OH HO OH =O CH C 3 O O =O CH C 2 OH HO OH 11-Deoxycortisol Cortisol Cortisone 18-Hydroxy-Corticosterone O =O CH C 2 OH C O H HO Aldosterone 5b-Pregnan-18-al 3a,11b,21-Trihydroxy-20-Oxo- 5b-Pregnan-18-al 11b, 21-Dihydroxy-3,20- 17a,21-Dihydroxy-5b- Pregnane-3,11,20-trione Urocortisone Urocortisol Cortol Cortolone Pregnane 3,20-dione 11b,17a 21-Trihydroxy-5b Glucuronides 3a-OH-5b-Pregnane-20-one 5b-Pregnane-3,20-dione HO CH C 3 H H Corticosterone -OH Pregnanediol Glucocorticoids * * Progesterone Degradation Cyp11a1 Steroid delta-Isomerase Corticosterone 18-Monooxy 3-Oxo-5b-Steroid Dh 3B-OH-delta-Steroid Dh 20b-Hydroxysteroid Dh Steroid delta-Isomerase Cortisone beta-reductase Cyp21a1 Cyp11b1 Cyp17a1 Cyp17a1 3B-OH-delta-Steroid Dh RGD:708361 (R)20-hydroxysteroid Dh RGD:708361 Hsd11b2 Hsd11b1 Name: Glucocorticoid Metabolism Last Modified: 5/2/2013 Organism: Rattus norvegicus
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Quality Tags
Fix interactions Comment: 376 out of 379 lines are not properly connected.
Please help improving this pathway by connecting the ends of interactions to nodes.
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Review changes for Approved Revision 116969 of this pathway was approved for data analysis by Martina Kutmon .
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Annotate nodes Comment: 16 out of 25 DataNodes have a missing external reference. Check DataNode table at the bottom of the page.
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