IL-4 signaling pathway (Mus musculus)

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InhibitionDAutophosphorylationDPhosphorylationDephosphorylationPalmitoylationENECDesumoylationEndosomeActivationDCY -> PMDReaction through unknown mechanisms/moleculesExtracellularEnzyme complexEndoplasmic reticulumControlProteins in a complex interactionDDNucleusPMGolgi apparatusMolecular associationMethylationGOLigandAcetylationDTranslocationMolecule in the pathwayDemethylationMTDeacetylationUbiquitinationProteolytic cleavage(Protein-protein interaction)MitochondrionNUPlasma membraneCY -> NUDDeubiquitinationCY -> PMCY -> PMERCytoplasmRecruitmentAccession Number: NetPath 16DGlycosylationCY -> PMCY -> NUReceptorCYSumoylationPrkcdJak1PrkczCblGene SymbolPik3caPIK3R1HIST2H3CStat6Cxcr4PrkcnPik3cdNfkb1Ptpn11Rasa1Socs1Irs2PrkcnDok2Irs1Socs3Stat6Pik3r2Grb2Jak2Akt1SrcPlcg1PrkciIl4raSfpi1Jak3Mapk1Ets1Mapk3FesNCF1PrkcdAdrbk2Nfkb1Il4Mapk11LckIl4raHmga1Mapk14Stat5aIl13ra1RPS6KB1Stat6Elk1CrebbpShc1Atf2StamStat6Il4Ep300Inpp5dPrkczJak2Tyk2Il2rgPtpn6PawrPrkciBadSos1Mapk14Stat6FynStat1Jak1Ptk2Socs5Bcl2l1Rela


Description

No description

Comments

GenMAPP notes 
NetPath 16 - IL-4 Signaling Pathway

NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.

GenMAPP remarks 
http://www.netpath.org

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
117991view11:23, 23 May 2021EweitzModified title
71761view20:27, 17 October 2013MaintBotremoved data source from nodes without identifier
69984view21:31, 11 July 2013MaintBotupdated to 2013 schema
67379view10:44, 26 June 2013Christine ChichesterOntology Term : 'interleukin-4 signaling pathway' added !
41293view00:22, 2 March 2011MaintBotRemoved redundant pathway information and comments
34389view22:50, 9 December 2009MaintBotAutomatic update of empty xrefs
28136view20:04, 27 January 2009KhanspersChanged name
20877view11:30, 14 November 2008MaintBot[[Pathway:Mus musculus:IL-4 NetPath 16]] moved to [[Pathway:WP93]]: Moved to stable identifier
8178view13:46, 7 January 2008MaintBot[[Pathway:Mouse:IL-4 NetPath 16]] moved to [[Pathway:Mus musculus:IL-4 NetPath 16]]: Renaming species
7709view16:11, 18 December 2007MaintBotfixed category names
7248view12:41, 4 November 2007MaintBotAdded categories to GPML
6461view22:19, 22 May 2007A.Pandeygpml file for [[Mouse:IL-4_NetPath_16]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Adrbk2GeneProduct320129 (Entrez Gene)
Akt1GeneProduct11651 (Entrez Gene)
Atf2GeneProduct11909 (Entrez Gene)
BadGeneProduct12015 (Entrez Gene)
Bcl2l1GeneProduct12048 (Entrez Gene)
CblGeneProduct12402 (Entrez Gene)
CrebbpGeneProduct12914 (Entrez Gene)
Cxcr4GeneProduct12767 (Entrez Gene)
Dok2GeneProduct13449 (Entrez Gene)
Elk1GeneProduct13712 (Entrez Gene)
Ep300GeneProduct328572 (Entrez Gene)
Ets1GeneProduct23871 (Entrez Gene)
FesGeneProduct14159 (Entrez Gene)
FynGeneProduct14360 (Entrez Gene)
Gene SymbolGeneProduct
Grb2GeneProduct14784 (Entrez Gene)
HIST2H3CGeneProduct
Hmga1GeneProduct15361 (Entrez Gene)
Il13ra1GeneProduct16164 (Entrez Gene)
Il2rgGeneProduct16186 (Entrez Gene)
Il4GeneProduct16189 (Entrez Gene)
Il4raGeneProduct16190 (Entrez Gene)
Inpp5dGeneProduct16331 (Entrez Gene)
Irs1GeneProduct16367 (Entrez Gene)
Irs2GeneProduct384783 (Entrez Gene)
Jak1GeneProduct16451 (Entrez Gene)
Jak2GeneProduct16452 (Entrez Gene)
Jak3GeneProduct16453 (Entrez Gene)
LckGeneProduct16818 (Entrez Gene)
Mapk11GeneProduct19094 (Entrez Gene)
Mapk1GeneProduct26413 (Entrez Gene)
Mapk14GeneProduct26416 (Entrez Gene)
Mapk3GeneProduct26417 (Entrez Gene)
NCF1GeneProduct17969 (Entrez Gene)
Nfkb1GeneProduct18033 (Entrez Gene)
PIK3R1GeneProduct18708 (Entrez Gene)
PawrGeneProduct114774 (Entrez Gene)
Pik3caGeneProduct18706 (Entrez Gene)
Pik3cdGeneProduct18707 (Entrez Gene)
Pik3r2GeneProduct18709 (Entrez Gene)
Plcg1GeneProduct18803 (Entrez Gene)
PrkcdGeneProduct18753 (Entrez Gene)
PrkciGeneProduct18759 (Entrez Gene)
PrkcnGeneProduct75292 (Entrez Gene)
PrkczGeneProduct18762 (Entrez Gene)
Ptk2GeneProduct14083 (Entrez Gene)
Ptpn11GeneProduct19247 (Entrez Gene)
Ptpn6GeneProduct15170 (Entrez Gene)
RPS6KB1GeneProduct72508 (Entrez Gene)
Rasa1GeneProduct218397 (Entrez Gene)
RelaGeneProduct19697 (Entrez Gene)
Sfpi1GeneProduct20375 (Entrez Gene)
Shc1GeneProduct20416 (Entrez Gene)
Socs1GeneProduct12703 (Entrez Gene)
Socs3GeneProduct12702 (Entrez Gene)
Socs5GeneProduct56468 (Entrez Gene)
Sos1GeneProduct20662 (Entrez Gene)
SrcGeneProduct20779 (Entrez Gene)
StamGeneProduct20844 (Entrez Gene)
Stat1GeneProduct20846 (Entrez Gene)
Stat5aGeneProduct20850 (Entrez Gene)
Stat6GeneProduct20852 (Entrez Gene)
Tyk2GeneProduct54721 (Entrez Gene)

Annotated Interactions

No annotated interactions
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