De novo biosynthesis of pyrimidine deoxyribonucleotides (Saccharomyces cerevisiae)
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H2O
dUDP
reduced thioredoxin
H2O
NH3
dTTP
reduced flavodoxin
UDP
oxidized thioredoxin
reduced thioredoxin
dUTP
oxidized thioredoxin
CTP
UTP
oxidized flavodoxin
H2O
7,8-dihydrofolate
H2O
oxidized flavodoxin
H2O
H2O
RNR4
ATP
ADP
dTDP
RNR4
YNK1
dCMP
CDC8
YNK1
CDC21
ATP
pyrophosphate
dUMP
5,10-methylene-THF
dUMP
ATP
RNR3
ATP
RNR2
ADP
DUT1
RNR1
RNR1
ADP
CDP
ATP
RNR3
RNR2
ADP
dTMP
dCDP
CDC8
ADP
dCTP
Description
No description
Comments
GenMAPP remarks
Based on
http://pathway.yeastgenome.org/biocyc/
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Quality Tags
Ontology Terms
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Bibliography
''de novo biosynthesis of pyrimidine deoxyribonucleotides''; YeastGenome,
History
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Compare
Revision
Action
Time
User
Comment
135637
view
04:54, 8 October 2024
Khanspers
Ontology Term : 'classic metabolic pathway' added !
135636
view
04:50, 8 October 2024
Khanspers
removed GenMAPP comments and updated reference
135635
view
04:49, 8 October 2024
Khanspers
Modified description
135634
view
04:48, 8 October 2024
Khanspers
overhaul
124941
view
06:57, 3 January 2023
Egonw
More metabolites as DataNode and connected lines
117280
view
10:46, 20 May 2021
Eweitz
Modified title
107020
view
13:47, 17 September 2019
MaintBot
HMDB identifier normalization
87228
view
14:47, 19 July 2016
Susan
Ontology Term : 'de novo pyrimidine biosynthetic pathway' added !
87227
view
14:47, 19 July 2016
Susan
Ontology Term : 'PW:0000861' removed !
87225
view
14:44, 19 July 2016
Susan
Ontology Term : 'pyrimidine biosynthetic pathway' added !
72053
view
17:07, 24 October 2013
Mkutmon
updated annotation for pyrophosphate
69864
view
17:26, 11 July 2013
Egonw
Marked a few DataNodes with CAS registry numbers as metabolites.
69612
view
20:33, 8 July 2013
MaintBot
Updated to 2013 gpml schema
41845
view
04:50, 2 March 2011
MaintBot
Removed redundant pathway information and comments
20753
view
11:29, 14 November 2008
MaintBot
[[Pathway:Saccharomyces cerevisiae:De Novo Biosynthesis of Pyrimidine Deoxyribonucleotides]] moved to [[Pathway:WP36]]: Moved to stable identifier
12684
view
07:57, 17 May 2008
MaintBot
automated metabolite conversion
8687
view
14:06, 7 January 2008
MaintBot
Added to category $category
8685
view
14:06, 7 January 2008
M.Braymer
Uploaded new pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
5,10-methylene-THF
Metabolite
31690-11-6 (CAS)
ADP
Metabolite
58-64-0 (CAS)
ATP
Metabolite
1927-31-7 (CAS)
CDC21
GeneProduct
S000005600 (SGD)
CDC8
GeneProduct
S000003818 (SGD)
CDP
Metabolite
63-38-7 (CAS)
DUT1
GeneProduct
S000000456 (SGD)
RNR1
GeneProduct
S000000872 (SGD)
RNR2
GeneProduct
S000003563 (SGD)
RNR3
GeneProduct
S000001328 (SGD)
RNR4
GeneProduct
S000003412 (SGD)
YNK1
GeneProduct
S000001550 (SGD)
dCDP
Metabolite
800-73-7 (CAS)
dCMP
Metabolite
1032-65-1 (CAS)
dCTP
Metabolite
2056-98-6 (CAS)
dTDP
Metabolite
491-97-4 (CAS)
dTMP
Metabolite
365-07-1 (CAS)
dUMP
Metabolite
964-26-1 (CAS)
pyrophosphate
Metabolite
HMDB00250 (HMDB)
Annotated Interactions
No annotated interactions
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Annotated Interactions
No annotated interactions