Oxidation by cytochrome P450 (Danio rerio)
From WikiPathways
Revision as of 20:48, 23 October 2013 by
Egonw
(
Talk
|
contribs
)
(
diff
)
←Older revision
|
Current revision
(
diff
) |
Newer revision→
(
diff
)
Jump to:
navigation
,
search
1
Cytochrome P450 genes
Substrate
zgc:112177
CYP4F2
O2
CYP2E1
CYP4F2
cyb5r3
cyp11a1
CYP4F2
cyp4
zgc:63986
cyp4
Substrate
Fe2+
cyp11b2
CYP2D6
CYP2C8
zgc:174342
CYP2B6
CYP3A5
dia1
CYP4F2
cyp4
NADH
cyp24a1l
cyp4v2
CYP2S1
cyb5b
si:dkey-69h9.1
Substrate
CYP2J2
activated O2
CYP2A7
cyp26c1
cyp26a1
CYP2C19
zgc:63920
Fe2+
CYP2C9
cyp27c1
CYP46A1
cyp11b2
zgc:153291
A9JRH5_DANRE
CYP
cyb5a
CYP2C18
LOC570455
cyp17a1
Substrate
NADP+
cyp2u1
cyb5b
cyp26b1
POR
cyp1b1
CYP2G1P
H2O
NAD+
CYP3A7
CYP27A1
Fe2+
cyp4
cyp51
CYP3A43
CYP
cyp1a
CYP
NADPH
CYP
CYP
CYP2A6
O2
LOC793249
CYP2W1
Substrate
cyp51
cyb5a
Fe2+
CYP3A4
CYP4F2
Fe3+
cyp1a
Fe3+
Substrate-OH
CYP4F2
CYP19A1
Fe3+
CYP2A13
CYP2F1
cyb5a
CYP27B1
cyp4
Fe3+
cyb5b
Description
Oxidation of a substrate by Cytochrome P450. Adapted from Niesink et al., Chapter 3, p. 47-48.
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP43(r29608)
with a 56% conversion rate.
Try the New WikiPathways
View approved pathways at
the new wikipathways.org
.
Quality Tags
Ontology Terms
Saving...
No Tags!
Bibliography
Niesink, R.J.M, Vries, de, J., Hollinger, M.A.; ''Toxicology; Principles and Applications''; , 1996
History
View all...
Compare
Revision
Action
Time
User
Comment
118187
view
10:51, 25 May 2021
Eweitz
Modified title
107100
view
14:18, 17 September 2019
MaintBot
ChEBI identifier normalization
106084
view
11:59, 16 August 2019
MaintBot
HMDB identifier normalization
88275
view
14:35, 1 August 2016
Fehrhart
Ontology Term : 'hepatocyte' added !
88274
view
14:35, 1 August 2016
Fehrhart
Ontology Term : 'phase I biotransformation pathway via cytochrome P450' added !
88273
view
14:35, 1 August 2016
Fehrhart
Ontology Term : 'xenobiotics biodegradation pathway' added !
73520
view
23:32, 29 January 2014
Khanspers
Modified title
71931
view
20:48, 23 October 2013
Egonw
Fixed the PubChem-compound data source.
68671
view
05:29, 6 July 2013
MaintBot
Updated to 2013 gpml schema
58797
view
22:46, 20 February 2013
MaintBot
Updated Ensembl and UniProt data source
48312
view
04:37, 18 May 2012
Khanspers
Updating PubChem xrefs
46428
view
20:47, 27 January 2012
MaintBot
Automatic update of PubChem xrefs
40844
view
22:19, 1 March 2011
MaintBot
Removed redundant pathway information and comments
34226
view
21:36, 9 December 2009
MaintBot
Automatic update of empty xrefs
31966
view
13:06, 14 August 2009
MaintBot
Fixed group labels
31102
view
01:42, 30 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
A9JRH5_DANRE
GeneProduct
ENSDARG00000056587 (Ensembl)
CYP
GeneProduct
CYP19A1
GeneProduct
CYP27A1
GeneProduct
CYP27B1
GeneProduct
ENSDARG00000045015 (Ensembl)
CYP2A13
GeneProduct
CYP2A6
GeneProduct
CYP2A7
GeneProduct
CYP2B6
GeneProduct
CYP2C18
GeneProduct
CYP2C19
GeneProduct
CYP2C8
GeneProduct
CYP2C9
GeneProduct
CYP2D6
GeneProduct
CYP2E1
GeneProduct
CYP2F1
GeneProduct
CYP2G1P
GeneProduct
CYP2J2
GeneProduct
CYP2S1
GeneProduct
CYP2W1
GeneProduct
CYP3A4
GeneProduct
CYP3A43
GeneProduct
CYP3A5
GeneProduct
CYP3A7
GeneProduct
CYP46A1
GeneProduct
553543 (Entrez Gene)
CYP4F2
GeneProduct
ENSDARG00000053530 (Ensembl)
Fe2+
Metabolite
29033 (ChEBI)
Fe3+
Metabolite
29034 (ChEBI)
H2O
Metabolite
962 (PubChem-compound)
LOC570455
GeneProduct
ENSDARG00000008858 (Ensembl)
LOC793249
GeneProduct
ENSDARG00000037550 (Ensembl)
NAD+
Metabolite
15846 (ChEBI)
NADH
Metabolite
16908 (ChEBI)
NADP+
Metabolite
18009 (ChEBI)
NADPH
Metabolite
16474 (ChEBI)
O2
Metabolite
HMDB01377 (HMDB)
POR
GeneProduct
568202 (Entrez Gene)
Substrate
GeneProduct
Substrate-OH
GeneProduct
activated O2
Metabolite
cyb5a
GeneProduct
ENSDARG00000055643 (Ensembl)
cyb5b
GeneProduct
ENSDARG00000053954 (Ensembl)
cyb5r3
GeneProduct
ENSDARG00000005891 (Ensembl)
cyp11a1
GeneProduct
ENSDARG00000002347 (Ensembl)
cyp11b2
GeneProduct
ENSDARG00000042014 (Ensembl)
cyp17a1
GeneProduct
ENSDARG00000033566 (Ensembl)
cyp1a
GeneProduct
ENSDARG00000026039 (Ensembl)
cyp1b1
GeneProduct
ENSDARG00000068934 (Ensembl)
cyp24a1l
GeneProduct
ENSDARG00000070420 (Ensembl)
cyp26a1
GeneProduct
ENSDARG00000033999 (Ensembl)
cyp26b1
GeneProduct
ENSDARG00000077121 (Ensembl)
cyp26c1
GeneProduct
ENSDARG00000056029 (Ensembl)
cyp27c1
GeneProduct
ENSDARG00000058439 (Ensembl)
cyp2u1
GeneProduct
ENSDARG00000026548 (Ensembl)
cyp4
GeneProduct
ENSDARG00000004964 (Ensembl)
cyp4v2
GeneProduct
ENSDARG00000062132 (Ensembl)
cyp51
GeneProduct
ENSDARG00000042641 (Ensembl)
dia1
GeneProduct
ENSDARG00000018966 (Ensembl)
si:dkey-69h9.1
GeneProduct
ENSDARG00000017982 (Ensembl)
zgc:112177
GeneProduct
ENSDARG00000020898 (Ensembl)
zgc:153291
GeneProduct
ENSDARG00000051925 (Ensembl)
zgc:174342
GeneProduct
ENSDARG00000053068 (Ensembl)
zgc:63920
GeneProduct
ENSDARG00000069018 (Ensembl)
zgc:63986
GeneProduct
ENSDARG00000006040 (Ensembl)
Annotated Interactions
No annotated interactions
Views
Pathway
Discussion
View source
Personal tools
Log in / create account
search
Help
About us
Contact us
Report a bug
How to cite
Quality control
Development
Publications using WikiPathways
Curation Events
Download
Download files
Other file formats
Web service API
WikiPathways RDF
Embed code
Activity
Browse pathways
Recent changes
New releases
New pathways
Edit pathways
Create pathway
Statistics
Tools
PathwayWidget
Pathway Finder
Software tools
Community Portals
Help on Portals
Adverse Outcome Pathways
Inherited Metabolic Disorders
CIRM
COVID-19
CPTAC
Diseases
ExRNA
Lipids
Micronutrients
Nanomaterials
NetPath
Plants
Rare Disease
Renal Genomics
Reactome
Skeletal Dysplasia
WormBase
Toolbox
What links here
Related changes
Upload file
Special pages
Printable version
Permanent link
Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
Ontology Terms
Bibliography
History
External references
DataNodes
Annotated Interactions
No annotated interactions