Electron transport chain (Mus musculus)

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F0 ComplexComplex VATP Synthase NADH-UbiquinoneOxidoreductaseComplex IIUbiquinol-Cytochrome CReductaseComplex IAdenine NucleotideTranslocatorUncoupling ProteinF1 ComplexC subunitIntermembraneSpaceCytochrome COxidaseComplex IVStalkSuccinate-UbiquinoneOxidoreductaseComplex IIIbinds ATP Synthase betaAssemblyMatrixSlc25a27NDUFB1e-UqcrbND4SdhcATP8ND6Ndufa7Uqcrc2Cox6b1COX2Ucp3SuccinateAtp5kCOX3Cox6a1COX7A3Cox7cH+Cox6a2Atp5g1H+CYTBNdufa12ND3H2OGm9763Atp5dAtp5eSlc25a5ND4LNdufc2e-1110020P15RikNdufb9H+Slc25a4Atp5lH+Ndufb5Atp5g2Ndufb3H+SdhbATPCox5aCox17Slc25a14Ndufb6Ndufa2Atpif1Cox7bAtp5j2Uqcrc1Ndufs1Ndufs5UqcrqNdufv1Atp5c1Cox5bCox8aNdufb10Ndufa4Cytochrome CNdufs6Ndufa10COX1Atp5jNdufa1Ndufab1Atp5hNdufs8Ndufa5e-ND2Uqcrfs1Ndufa6Atp5a1Cox7a2ATP6Krebs CycleH+Ndufs3Cox4i1Ndufc1Ndufa3Ndufs7Ndufa8NADHNdufb8SdhdO2Gm5560Atp5g3Atp5sNdufs4Ndufb7UqcrCox6cNAD+FADNdufs2Cox15FADH2Atp5oAtp5bSdhaCox11Ndufv3Ndufa9ND1Ndufv2ND5Ucp2Ucp1Sco1UbiquinoneCox7a2lAtp5f1H+Ndufb4Ndufb2Surf1Cox7a1


Description

An electron transport chain(ETC) couples a chemical reaction between an electron donor (such as NADH) and an electron acceptor (such as O2) to the transfer of H+ ions across a membrane, through a set of mediating biochemical reactions. These H+ ions are used to produce adenosine triphosphate (ATP), the main energy intermediate in living organisms, as they move back across the membrane.

In mitochondria, it is the conversion of oxygen to water, NADH to NAD+ and succinate to fumarate that drives the transfer of H+ ions.

Source: Wikipedia (wikipedia:Electron_transport_chain)

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP111(r20917) with a 70% conversion rate.

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Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
117879view10:21, 23 May 2021EweitzModified title
115463view08:21, 21 February 2021EgonwOne more pathway clickable
107966view09:31, 18 November 2019Fehrhartconnected unconnected line
107945view19:39, 12 November 2019PapaxModified title
106875view13:35, 17 September 2019MaintBotHMDB identifier normalization
95791view14:40, 19 January 2018MkutmonHomology conversion update
89980view18:47, 6 October 2016Mkutmonfix unconnected lines
79459view12:57, 22 March 2015EgonwFixed the data source which I forgot to update.
79217view13:32, 15 March 2015EgonwReplaced the HMDB H2 identifier with H+ from ChEBI.
74377view21:31, 15 April 2014Khanspersadjusted layout
74376view21:29, 15 April 2014Khanspersadded pathway node
71739view20:18, 17 October 2013MaintBotAutomated update of data sources
71324view17:17, 17 October 2013MaintBotAutomated update of data sources
69136view18:16, 8 July 2013MaintBotUpdated to 2013 gpml schema
67191view10:18, 26 June 2013Christine ChichesterOntology Term : 'electron transport chain pathway' added !
62836view04:55, 3 May 2013MaintBotUpdated UniProt data source
41324view00:24, 2 March 2011MaintBotRemoved redundant pathway information and comments
35239view19:45, 11 February 2010AlexanderPicoModified description
34398view22:57, 9 December 2009MaintBotAutomatic update of empty xrefs
32868view21:13, 16 September 2009MaintBotAdded more xrefs
32867view18:16, 16 September 2009MaintBotadding xrefs
32389view16:58, 15 August 2009MaintBotFixed text labels
32033view13:26, 14 August 2009MaintBotFixed group labels
31424view20:59, 13 August 2009MaintBotFixed text labels
30843view00:05, 30 July 2009MaintBotConverted from Homo sapiens
21301view11:31, 14 November 2008MaintBot[[Pathway:Mus musculus:Electron Transport Chain]] moved to [[Pathway:WP295]]: Moved to stable identifier
8010view13:46, 7 January 2008MaintBot[[Pathway:Mouse:Electron Transport Chain]] moved to [[Pathway:Mus musculus:Electron Transport Chain]]: Renaming species
7628view16:05, 18 December 2007MaintBotfixed category names
7341view12:42, 4 November 2007MaintBotAdded categories to GPML
19422view22:18, 22 May 2007M.Braymergpml file for [[Mouse:Electron_Transport_Chain]]
6435view22:18, 22 May 2007Kdahlquistgpml file for [[Mouse:Electron_Transport_Chain]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
1110020P15RikGeneProduct66152 (Entrez Gene)
ATP6GeneProduct17705 (Entrez Gene)
ATP8GeneProduct17706 (Entrez Gene)
ATPMetaboliteC00002 (KEGG Compound)
Atp5a1GeneProduct11946 (Entrez Gene)
Atp5bGeneProduct11947 (Entrez Gene)
Atp5c1GeneProduct11949 (Entrez Gene)
Atp5dGeneProduct66043 (Entrez Gene)
Atp5eGeneProduct67126 (Entrez Gene)
Atp5f1GeneProduct11950 (Entrez Gene)
Atp5g1GeneProduct11951 (Entrez Gene)
Atp5g2GeneProduct67942 (Entrez Gene)
Atp5g3GeneProduct228033 (Entrez Gene)
Atp5hGeneProduct71679 (Entrez Gene)
Atp5jGeneProduct11957 (Entrez Gene)
Atp5j2GeneProduct57423 (Entrez Gene)
Atp5kGeneProduct11958 (Entrez Gene)
Atp5lGeneProduct27425 (Entrez Gene)
Atp5oGeneProduct28080 (Entrez Gene)
Atp5sGeneProduct68055 (Entrez Gene)
Atpif1GeneProduct11983 (Entrez Gene)
COX1GeneProduct17708 (Entrez Gene)
COX2GeneProduct17709 (Entrez Gene)
COX3GeneProduct17710 (Entrez Gene)
COX7A3GeneProduct
CYTBGeneProduct17711 (Entrez Gene)
Cox11GeneProduct69802 (Entrez Gene)
Cox15GeneProduct226139 (Entrez Gene)
Cox17GeneProduct12856 (Entrez Gene)
Cox4i1GeneProduct12857 (Entrez Gene)
Cox5aGeneProduct12858 (Entrez Gene)
Cox5bGeneProduct12859 (Entrez Gene)
Cox6a1GeneProduct12861 (Entrez Gene)
Cox6a2GeneProduct12862 (Entrez Gene)
Cox6b1GeneProduct110323 (Entrez Gene)
Cox6cGeneProduct12864 (Entrez Gene)
Cox7a1GeneProduct12865 (Entrez Gene)
Cox7a2GeneProduct12866 (Entrez Gene)
Cox7a2lGeneProduct20463 (Entrez Gene)
Cox7bGeneProduct66142 (Entrez Gene)
Cox7cGeneProduct12867 (Entrez Gene)
Cox8aGeneProduct12868 (Entrez Gene)
Cytochrome CMetaboliteC00524 (KEGG Compound)
FADMetaboliteC00016 (KEGG Compound)
FADH2MetaboliteC01352 (KEGG Compound)
Gm5560GeneProduct433923 (Entrez Gene)
Gm9763GeneProduct100042918 (Entrez Gene)
H+MetaboliteHMDB01362 (HMDB)
H2OMetaboliteHMDB02111 (HMDB)
Krebs CyclePathwayWP434 (WikiPathways)
NAD+MetaboliteC00003 (KEGG Compound)
NADHMetaboliteC00004 (KEGG Compound)
ND1GeneProduct17716 (Entrez Gene)
ND2GeneProduct17717 (Entrez Gene)
ND3GeneProduct17718 (Entrez Gene)
ND4GeneProduct17719 (Entrez Gene)
ND4LGeneProduct17720 (Entrez Gene)
ND5GeneProduct17721 (Entrez Gene)
ND6GeneProduct17722 (Entrez Gene)
NDUFB1GeneProduct
Ndufa10GeneProduct67273 (Entrez Gene)
Ndufa12GeneProduct66414 (Entrez Gene)
Ndufa1GeneProduct54405 (Entrez Gene)
Ndufa2GeneProduct17991 (Entrez Gene)
Ndufa3GeneProduct66091 (Entrez Gene)
Ndufa4GeneProduct17992 (Entrez Gene)
Ndufa5GeneProduct68202 (Entrez Gene)
Ndufa6GeneProduct67130 (Entrez Gene)
Ndufa7GeneProduct66416 (Entrez Gene)
Ndufa8GeneProduct68375 (Entrez Gene)
Ndufa9GeneProduct66108 (Entrez Gene)
Ndufab1GeneProduct70316 (Entrez Gene)
Ndufb10GeneProduct68342 (Entrez Gene)
Ndufb2GeneProduct68198 (Entrez Gene)
Ndufb3GeneProduct66495 (Entrez Gene)
Ndufb4GeneProduct68194 (Entrez Gene)
Ndufb5GeneProduct66046 (Entrez Gene)
Ndufb6GeneProduct230075 (Entrez Gene)
Ndufb7GeneProduct66916 (Entrez Gene)
Ndufb8GeneProduct67264 (Entrez Gene)
Ndufb9GeneProduct66218 (Entrez Gene)
Ndufc1GeneProduct66377 (Entrez Gene)
Ndufc2GeneProduct68197 (Entrez Gene)
Ndufs1GeneProduct227197 (Entrez Gene)
Ndufs2GeneProduct226646 (Entrez Gene)
Ndufs3GeneProduct68349 (Entrez Gene)
Ndufs4GeneProduct17993 (Entrez Gene)
Ndufs5GeneProduct595136 (Entrez Gene)
Ndufs6GeneProduct407785 (Entrez Gene)
Ndufs7GeneProduct75406 (Entrez Gene)
Ndufs8GeneProduct225887 (Entrez Gene)
Ndufv1GeneProduct17995 (Entrez Gene)
Ndufv2GeneProduct72900 (Entrez Gene)
Ndufv3GeneProduct78330 (Entrez Gene)
O2MetaboliteHMDB01377 (HMDB)
Sco1GeneProduct52892 (Entrez Gene)
SdhaGeneProduct66945 (Entrez Gene)
SdhbGeneProduct67680 (Entrez Gene)
SdhcGeneProduct66052 (Entrez Gene)
SdhdGeneProduct66925 (Entrez Gene)
Slc25a14GeneProduct20523 (Entrez Gene)
Slc25a27GeneProduct74011 (Entrez Gene)
Slc25a4GeneProduct11739 (Entrez Gene)
Slc25a5GeneProduct11740 (Entrez Gene)
SuccinateMetaboliteC00042 (KEGG Compound)
Surf1GeneProduct20930 (Entrez Gene)
UbiquinoneMetabolite
Ucp1GeneProduct22227 (Entrez Gene)
Ucp2GeneProduct22228 (Entrez Gene)
Ucp3GeneProduct22229 (Entrez Gene)
UqcrGeneProduct66594 (Entrez Gene)
UqcrbGeneProduct67530 (Entrez Gene)
Uqcrc1GeneProduct22273 (Entrez Gene)
Uqcrc2GeneProduct67003 (Entrez Gene)
Uqcrfs1GeneProduct66694 (Entrez Gene)
UqcrqGeneProduct22272 (Entrez Gene)
e-MetaboliteC05359 (KEGG Compound)

Annotated Interactions

No annotated interactions
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