Metapathway biotransformation (Equus caballus)

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Glutathione conjugationEpoxide hydrolasesElectrophilesMethylationAldo-keto reductasesCytochrome P450Glutathione transferasesReductionHydrolysisGlucuronidationAmino acid conjugationMethyltransferasesAmino acid acyl transferasesN-acetyltransferasesGlutathione synthetaseOxidationSulfotransferasesSulfationGlutathione reductaseGlutathione peroxidasesGlucuronosyltransferasesNucleophilesFlavin monooxygenasesAcetylationXP_001503353.1CYP3A4XP_001497396.2Glutathione transferaseGPX2XP_001500553.1NAT8Substrate-CH3Substrate-SO3HXP_001916527.1CYP4F11Substrate=OCHST7UGT1A10UGT2A2Q9N2C4_HORSEXP_001501941.1Substrate-SGCYP11B1AKR7A2HS3ST3B1XP_001496962.1XP_001492328.1Amino acid acyltransferaseUGT1A6CYP2S1Substrate-AaXP_001489266.1XP_001502088.1XP_001502088.1XP_001488205.2SulfotransferaseXP_001501478.2CYP2A13CHST1XP_001493558.1GSTA3XP_001489453.1XP_001502088.1MGST2XP_001488979.2CYP11B2Substrate-GlXP_001493411.1HS6ST2CYP2C19Q2LE11_HORSESubstrate-OHXP_001493338.1UGT2B15XP_001499427.2XP_001498955.2Substrate-O-RUGT1A1XP_001487907.1XP_001914769.1XP_001503157.1XP_001503107.2XP_001492728.1XP_001493215.1GSTT2XP_001495217.1GPX4NNMTCYP2C9A8WDL7_HORSECYP4F3GlucuronosyltransferaseUGT1A9KCNAB2XP_001916131.1XP_001490376.2XP_001915852.1AKR1C2UGT2A1UGT1A8Aldo-keto reductaseAKR1C4XP_001504142.1XP_001498224.1XP_001918021.1GSTM1HS3ST4SULT2A1Substrate-SHXP_001495454.2CYP4F2XP_001498871.1XP_001490382.2CP11A_HORSEXP_001502088.1XP_001503655.1HS3ST3A1CHST14CYP3A43CYP4F8NAT10XP_001496254.1XP_001500782.1CHST2GSTA2CYP2W1CYP2C18XP_001504071.1CHST13CYP21A2Flavin monooxygenaseXP_001497124.1AKR1B10XP_001501402.2CYP450CYP2D6N-acetyltransferaseXP_001499929.2SULT2B1XP_001918061.1UGT2B17AKR1C1UGT1A3NAT6CHST9XP_001492219.1XP_001498449.2XP_001501008.1UGT2B28XP_001499231.2CYP2A6XP_001490613.2Substrate-NH2GSTM5XP_001494003.2XP_001502548.1XP_001505104.1CYP2C8CYP4B1XP_001504849.2XP_001504745.1CYP4F12CYP46A1XP_001503761.1XP_001499815.2UGT2B7TPMT_HORSEXP_001488543.2XP_001503966.1XP_001492725.1XP_001487907.1COMTXP_001494608.1CYP3A7XP_001501166.1XP_001492270.2XP_001491520.1UGT2A3GSTM2XP_001918060.1XP_001488867.2GLYATL1GLYATL2XP_001489868.1XP_001491545.2SULT1E1MethyltransferaseUGT1A7XP_001503816.1AKR1C3XP_001493525.2UGT2B4XP_001494941.2CYP2A7XP_001492298.2XP_001496001.1CP17A_HORSEGSTT2BXP_001503334.1XP_001489957.2XP_001489979.1XP_001487968.2XP_001489035.1XP_001498220.1XP_001493936.1CP19A_HORSEGSTA5CYP26C1XP_001915539.1Substrate-AcXP_001500863.2XP_001498871.1XP_001917301.1XP_001489097.1UGT1A4Xenobiotic substrateA8WCD7_HORSEGSTP1XP_001498064.1CYP2B6XP_001497881.2CYP4Z1XP_001495936.1Q4TUB6_HORSEXP_001915244.1XP_001496075.2SULT1C4UGT2B11GSTA1CYP3A5XP_001499416.2SULT1B1UGT1A5


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP702(r29945) with a 57% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
87791view11:14, 25 July 2016ElisaOntology Term : 'classic metabolic pathway' added !
74522view21:41, 28 April 2014KhanspersModified title
68745view22:55, 6 July 2013MaintBotUpdated to 2013 gpml schema
58878view00:33, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
40918view22:41, 1 March 2011MaintBotRemoved redundant pathway information and comments
33199view18:23, 5 November 2009KhanspersModified categories
32278view13:07, 15 August 2009MaintBotFixed text labels
31821view12:24, 14 August 2009MaintBotFixed group labels
31306view20:12, 13 August 2009MaintBotFixed text labels
30781view23:30, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
A8WCD7_HORSEGeneProductENSECAG00000013817 (Ensembl)
A8WDL7_HORSEGeneProductENSECAG00000019088 (Ensembl)
AKR1B10GeneProduct
AKR1C1GeneProduct
AKR1C2GeneProduct
AKR1C3GeneProduct
AKR1C4GeneProduct
AKR7A2GeneProduct
Aldo-keto reductaseGeneProduct
Amino acid acyltransferaseGeneProduct
CHST1GeneProduct
CHST13GeneProduct
CHST14GeneProduct
CHST2GeneProductENSECAG00000000982 (Ensembl)
CHST7GeneProduct
CHST9GeneProduct
COMTGeneProduct
CP11A_HORSEGeneProductENSECAG00000017494 (Ensembl)
CP17A_HORSEGeneProductENSECAG00000010022 (Ensembl)
CP19A_HORSEGeneProductENSECAG00000020474 (Ensembl)
CYP11B1GeneProduct
CYP11B2GeneProduct
CYP21A2GeneProduct
CYP26C1GeneProductENSECAG00000023734 (Ensembl)
CYP2A13GeneProduct
CYP2A6GeneProduct
CYP2A7GeneProduct
CYP2B6GeneProduct
CYP2C18GeneProduct
CYP2C19GeneProduct
CYP2C8GeneProduct
CYP2C9GeneProduct
CYP2D6GeneProduct
CYP2S1GeneProductENSECAG00000009026 (Ensembl)
CYP2W1GeneProductENSECAG00000022978 (Ensembl)
CYP3A4GeneProduct
CYP3A43GeneProduct
CYP3A5GeneProduct
CYP3A7GeneProduct
CYP450GeneProduct
CYP46A1GeneProductENSECAG00000007407 (Ensembl)
CYP4B1GeneProduct
CYP4F11GeneProduct
CYP4F12GeneProduct
CYP4F2GeneProduct
CYP4F3GeneProduct
CYP4F8GeneProduct
CYP4Z1GeneProduct
Flavin monooxygenaseGeneProduct
GLYATL1GeneProduct
GLYATL2GeneProduct
GPX2GeneProduct
GPX4GeneProduct
GSTA1GeneProduct
GSTA2GeneProduct
GSTA3GeneProduct
GSTA5GeneProduct
GSTM1GeneProduct
GSTM2GeneProduct
GSTM5GeneProduct
GSTP1GeneProduct
GSTT2GeneProduct
GSTT2BGeneProduct
GlucuronosyltransferaseGeneProduct
Glutathione transferaseGeneProduct
HS3ST3A1GeneProduct
HS3ST3B1GeneProduct
HS3ST4GeneProduct
HS6ST2GeneProductENSECAG00000024375 (Ensembl)
KCNAB2GeneProductENSECAG00000011806 (Ensembl)
MGST2GeneProductENSECAG00000019195 (Ensembl)
MethyltransferaseGeneProduct
N-acetyltransferaseGeneProduct
NAT10GeneProductENSECAG00000011621 (Ensembl)
NAT6GeneProduct
NAT8GeneProduct
NNMTGeneProduct
Q2LE11_HORSEGeneProductENSECAG00000025143 (Ensembl)
Q4TUB6_HORSEGeneProductENSECAG00000009019 (Ensembl)
Q9N2C4_HORSEGeneProductENSECAG00000000745 (Ensembl)
SULT1B1GeneProduct
SULT1C4GeneProduct
SULT1E1GeneProduct
SULT2A1GeneProduct
SULT2B1GeneProductENSECAG00000015059 (Ensembl)
Substrate-AaMetabolite
Substrate-AcMetabolite
Substrate-CH3Metabolite
Substrate-GlMetabolite
Substrate-NH2Metabolite
Substrate-O-RMetabolite
Substrate-OHMetabolite
Substrate-SGMetabolite
Substrate-SHMetabolite
Substrate-SO3HMetabolite
Substrate=OMetabolite
SulfotransferaseGeneProduct
TPMT_HORSEGeneProductENSECAG00000013653 (Ensembl)
UGT1A1GeneProduct
UGT1A10GeneProduct
UGT1A3GeneProduct
UGT1A4GeneProduct
UGT1A5GeneProduct
UGT1A6GeneProduct
UGT1A7GeneProduct
UGT1A8GeneProductENSECAG00000023519 (Ensembl)
UGT1A9GeneProduct
UGT2A1GeneProduct
UGT2A2GeneProduct
UGT2A3GeneProductENSECAG00000014362 (Ensembl)
UGT2B11GeneProduct
UGT2B15GeneProduct
UGT2B17GeneProduct
UGT2B28GeneProduct
UGT2B4GeneProduct
UGT2B7GeneProduct
XP_001487907.1GeneProductENSECAG00000002652 (Ensembl)
XP_001487968.2GeneProductENSECAG00000013205 (Ensembl)
XP_001488205.2GeneProductENSECAG00000017379 (Ensembl)
XP_001488543.2GeneProductENSECAG00000009867 (Ensembl)
XP_001488867.2GeneProductENSECAG00000022724 (Ensembl)
XP_001488979.2GeneProductENSECAG00000016322 (Ensembl)
XP_001489035.1GeneProductENSECAG00000019677 (Ensembl)
XP_001489097.1GeneProductENSECAG00000008591 (Ensembl)
XP_001489266.1GeneProductENSECAG00000000898 (Ensembl)
XP_001489453.1GeneProductENSECAG00000002100 (Ensembl)
XP_001489868.1GeneProductENSECAG00000017766 (Ensembl)
XP_001489957.2GeneProductENSECAG00000012609 (Ensembl)
XP_001489979.1GeneProductENSECAG00000022803 (Ensembl)
XP_001490376.2GeneProductENSECAG00000011592 (Ensembl)
XP_001490382.2GeneProductENSECAG00000016889 (Ensembl)
XP_001490613.2GeneProductENSECAG00000006802 (Ensembl)
XP_001491520.1GeneProductENSECAG00000006455 (Ensembl)
XP_001491545.2GeneProductENSECAG00000012925 (Ensembl)
XP_001492219.1GeneProductENSECAG00000020768 (Ensembl)
XP_001492270.2GeneProductENSECAG00000006012 (Ensembl)
XP_001492298.2GeneProductENSECAG00000001066 (Ensembl)
XP_001492328.1GeneProductENSECAG00000019737 (Ensembl)
XP_001492725.1GeneProductENSECAG00000023444 (Ensembl)
XP_001492728.1GeneProductENSECAG00000013059 (Ensembl)
XP_001493215.1GeneProductENSECAG00000008834 (Ensembl)
XP_001493338.1GeneProductENSECAG00000020703 (Ensembl)
XP_001493411.1GeneProductENSECAG00000011265 (Ensembl)
XP_001493525.2GeneProductENSECAG00000020100 (Ensembl)
XP_001493558.1GeneProductENSECAG00000022320 (Ensembl)
XP_001493936.1GeneProductENSECAG00000008153 (Ensembl)
XP_001494003.2GeneProductENSECAG00000014178 (Ensembl)
XP_001494608.1GeneProductENSECAG00000000800 (Ensembl)
XP_001494941.2GeneProductENSECAG00000018909 (Ensembl)
XP_001495217.1GeneProductENSECAG00000024451 (Ensembl)
XP_001495454.2GeneProductENSECAG00000018832 (Ensembl)
XP_001495936.1GeneProductENSECAG00000000223 (Ensembl)
XP_001496001.1GeneProductENSECAG00000012649 (Ensembl)
XP_001496075.2GeneProductENSECAG00000019741 (Ensembl)
XP_001496254.1GeneProductENSECAG00000013478 (Ensembl)
XP_001496962.1GeneProductENSECAG00000012946 (Ensembl)
XP_001497124.1GeneProductENSECAG00000011289 (Ensembl)
XP_001497396.2GeneProductENSECAG00000023905 (Ensembl)
XP_001497881.2GeneProductENSECAG00000021338 (Ensembl)
XP_001498064.1GeneProductENSECAG00000006553 (Ensembl)
XP_001498220.1GeneProductENSECAG00000007161 (Ensembl)
XP_001498224.1GeneProductENSECAG00000019834 (Ensembl)
XP_001498449.2GeneProductENSECAG00000019904 (Ensembl)
XP_001498871.1GeneProductENSECAG00000023425 (Ensembl)
XP_001498955.2GeneProductENSECAG00000018711 (Ensembl)
XP_001499231.2GeneProductENSECAG00000021620 (Ensembl)
XP_001499416.2GeneProductENSECAG00000010116 (Ensembl)
XP_001499427.2GeneProductENSECAG00000011560 (Ensembl)
XP_001499815.2GeneProductENSECAG00000019442 (Ensembl)
XP_001499929.2GeneProductENSECAG00000009434 (Ensembl)
XP_001500553.1GeneProductENSECAG00000014579 (Ensembl)
XP_001500782.1GeneProductENSECAG00000014271 (Ensembl)
XP_001500863.2GeneProductENSECAG00000007127 (Ensembl)
XP_001501008.1GeneProductENSECAG00000002570 (Ensembl)
XP_001501166.1GeneProductENSECAG00000023208 (Ensembl)
XP_001501402.2GeneProductENSECAG00000017089 (Ensembl)
XP_001501478.2GeneProductENSECAG00000003415 (Ensembl)
XP_001501941.1GeneProductENSECAG00000020763 (Ensembl)
XP_001502088.1GeneProductENSECAG00000021518 (Ensembl)
XP_001502548.1GeneProductENSECAG00000022244 (Ensembl)
XP_001503107.2GeneProductENSECAG00000021232 (Ensembl)
XP_001503157.1GeneProductENSECAG00000019037 (Ensembl)
XP_001503334.1GeneProductENSECAG00000022398 (Ensembl)
XP_001503353.1GeneProductENSECAG00000023013 (Ensembl)
XP_001503655.1GeneProductENSECAG00000009590 (Ensembl)
XP_001503761.1GeneProductENSECAG00000017361 (Ensembl)
XP_001503816.1GeneProductENSECAG00000008012 (Ensembl)
XP_001503966.1GeneProductENSECAG00000018379 (Ensembl)
XP_001504071.1GeneProductENSECAG00000015421 (Ensembl)
XP_001504142.1GeneProductENSECAG00000018033 (Ensembl)
XP_001504745.1GeneProductENSECAG00000006770 (Ensembl)
XP_001504849.2GeneProductENSECAG00000011019 (Ensembl)
XP_001505104.1GeneProductENSECAG00000004503 (Ensembl)
XP_001914769.1GeneProductENSECAG00000012358 (Ensembl)
XP_001915244.1GeneProductENSECAG00000000862 (Ensembl)
XP_001915539.1GeneProductENSECAG00000001117 (Ensembl)
XP_001915852.1GeneProductENSECAG00000007540 (Ensembl)
XP_001916131.1GeneProductENSECAG00000018442 (Ensembl)
XP_001916527.1GeneProductENSECAG00000003050 (Ensembl)
XP_001917301.1GeneProductENSECAG00000006082 (Ensembl)
XP_001918021.1GeneProductENSECAG00000010884 (Ensembl)
XP_001918060.1GeneProductENSECAG00000024971 (Ensembl)
XP_001918061.1GeneProductENSECAG00000007597 (Ensembl)
Xenobiotic substrateMetabolite

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1212"
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