TGF-beta signaling pathway (Drosophila melanogaster)

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Cofactorsligands:TGFbCo-SmadsRsmadsCofactorR-SmadsAccessory receptors:HOMOLOGY MAPPRepressorsCo-smadsTGFBR3MAPK3SERPINE1ENGTGFB1SMAD5FKBP1AFOSSMAD1TFE3ZFHX1BNOGJUNWNT1HRASFSTTGFB1TGFBR2IFNGRUNX2ITGB6RUNX3LEF1SMAD2TGFBR1SKILSMAD9FOXH1CTNNB1NFKB1ZFYVE9TGFBR2EGFLIFZNF423THBS1TNFBMP4SMAD6STAT1MAPK9SMAD1TNFSMAD4INHBAEP300TGFBR1SKISMAD2LTBP1TGIFBAMBISTAT3BMP4SMAD7SMAD3JAK1SPP1CREBBP


Description

No description

Comments

GenMAPP notes 
Further reading: Massague J. et al. Cell. 2000 Oct 13;103(2):295-309. , and Nat Rev Mol Cell Biol. 2000 Dec 1(3):169-78.
GenMAPP remarks 
edited by: Nathan Salomonis

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Bibliography

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History

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CompareRevisionActionTimeUserComment
116496view10:30, 7 May 2021EweitzModified title
79499view15:44, 23 March 2015Ryan.miller
79363view19:20, 21 March 2015Khanspersupdate schema
79362view19:19, 21 March 2015KhanspersReverted to version '11:50, 26 June 2013' by Khanspers
68713view21:39, 6 July 2013MaintBotUpdated to 2013 gpml schema
67693view11:50, 26 June 2013DdiglesOntology Term : 'transforming growth factor-beta superfamily mediated signaling pathway' added !
40881view22:34, 1 March 2011MaintBotRemoved redundant pathway information and comments
21161view11:30, 14 November 2008MaintBot[[Pathway:Drosophila melanogaster:TGF Beta Signaling Pathway]] moved to [[Pathway:WP230]]: Moved to stable identifier
8525view14:02, 7 January 2008MaintBotAdded to category $category
8523view14:02, 7 January 2008N.GalUploaded new pathway

External references

DataNodes

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NameTypeDatabase referenceComment
BAMBIGeneProduct
BMP4GeneProduct
CREBBPGeneProduct
CTNNB1GeneProduct31151 (Entrez Gene)
EGFGeneProduct
ENGGeneProduct
EP300GeneProduct43856 (Entrez Gene)
FKBP1AGeneProduct37214 (Entrez Gene)
FOSGeneProduct
FOXH1GeneProduct
FSTGeneProduct2768836 (Entrez Gene)
HRASGeneProduct
IFNGGeneProduct
INHBAGeneProduct
ITGB6GeneProduct
JAK1GeneProduct
JUNGeneProduct
LEF1GeneProduct
LIFGeneProduct
LTBP1GeneProduct
MAPK3GeneProduct
MAPK9GeneProduct
NFKB1GeneProduct
NOGGeneProduct
RUNX2GeneProduct33051 (Entrez Gene)
RUNX3GeneProduct
SERPINE1GeneProduct
SKIGeneProduct34085 (Entrez Gene)
SKILGeneProduct
SMAD1GeneProduct33529 (Entrez Gene)
SMAD2GeneProduct31738 (Entrez Gene)
SMAD3GeneProduct
SMAD4GeneProduct43725 (Entrez Gene)
SMAD5GeneProduct
SMAD6GeneProduct
SMAD7GeneProduct42059 (Entrez Gene)
SMAD9GeneProduct
SPP1GeneProduct
STAT1GeneProduct
STAT3GeneProduct
TFE3GeneProduct
TGFB1GeneProduct
TGFBR1GeneProduct35900 (Entrez Gene)
TGFBR2GeneProduct
TGFBR3GeneProduct
TGIFGeneProduct
THBS1GeneProductthere are 5 types of tsp
TNFGeneProduct
WNT1GeneProduct34009 (Entrez Gene)
ZFHX1BGeneProduct
ZFYVE9GeneProduct44263 (Entrez Gene)
ZNF423GeneProduct36609 (Entrez Gene)

Annotated Interactions

No annotated interactions
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