Translation factors (Bos taurus)

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1m7GCap Binding ComplexAAAAAAAAAAAAAAARecruitment of 43SPre-initiation Complex40S SubunitGuanine Nucleotide ExchangeElongationscanningTerminationmRNARecruitment of 60S subunitand first peptide bondBinds aminoacyl-tRNATranslocation60S SubunitInitiation43S Pre-initiation ComplexAUGEIF4G1EIF3AEIF4EBP3EIF4EBP2EEF1A1EIF4A1EIF1AYEIF1EIF3BEIF4EBP1EEF2EIF3JEIF5AEIF4EEIF2B4EEF2KEIF1AXEIF6EIF2S2EIF5EIF4A2EIF3EEIF4BEIF2B5EEF1BEIF2B2EEF1GEIF2AK3WBSCR1PAIP1EIF2AK1EEF1A2EIF2AK2EIF2B1EIF4G3EIF5BGSPT2ETF1EIF3DCLUHEIF3CEIF2S1EIF3HEIF2S3EIF3FPABPC1EIF3GEIF3IEIF1EEF1DEIF2B3


Description

Protein synthesis is the ultimate step of gene expression and a key control point for regulation. In particular, it enables cells to rapidly manipulate protein production without new mRNA synthesis, processing, or export. This pathway gives an overview of the translation factors involved in this process.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP107(78489) with a 94.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Dever TE; ''Gene-specific regulation by general translation factors.''; Cell, 2002 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
117628view11:44, 21 May 2021EweitzModified title
80725view15:23, 30 June 2015Mkutmonhomology conversion
63460view17:18, 10 May 2013MaintBotUpdated to 2013 gpml schema
40595view19:33, 1 March 2011MaintBotRemoved redundant pathway information and comments
33832view00:29, 9 December 2009MaintBotAutomatic update of empty xrefs
33614view10:00, 1 December 2009MaintBotRemoved group label
31627view22:21, 13 August 2009MaintBotFixed text labels
30534view21:54, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
CLUHGeneProductENSBTAG00000011786 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:23277
EEF1A1GeneProductENSBTAG00000046034 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1915
EEF1A2GeneProductENSBTAG00000021685 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1917
EEF1BGeneProductENSBTAG00000021979 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1933
EEF1DGeneProductENSBTAG00000014643 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1936
EEF1GGeneProductENSBTAG00000011843 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1937
EEF2GeneProductENSBTAG00000004258 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1938
EEF2KGeneProductENSBTAG00000017662 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:29904
EIF1AXGeneProductENSBTAG00000017633 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1964
EIF1AYGeneProduct
EIF1GeneProductENSBTAG00000046450 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10209
EIF2AK1GeneProductENSBTAG00000007370 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:27102
EIF2AK2GeneProductENSBTAG00000008703 (Ensembl)
  • now E2K2 HUMAN
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5610
EIF2AK3GeneProductENSBTAG00000000184 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9451
EIF2B1GeneProductENSBTAG00000007269 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1967
EIF2B2GeneProductENSBTAG00000008664 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8892
EIF2B3GeneProductENSBTAG00000019010 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8891
EIF2B4GeneProductENSBTAG00000019510 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8890
EIF2B5GeneProductENSBTAG00000011414 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8893
EIF2S1GeneProductENSBTAG00000016311 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1965
EIF2S2GeneProductENSBTAG00000005969 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8894
EIF2S3GeneProductENSBTAG00000014337 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1968
EIF3AGeneProductENSBTAG00000002528 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8661
EIF3BGeneProductENSBTAG00000007474 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8662
EIF3CGeneProductENSBTAG00000006543 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8663
EIF3DGeneProductENSBTAG00000001988 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8664
EIF3EGeneProductENSBTAG00000006702 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3646
EIF3FGeneProductENSBTAG00000004861 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8665
EIF3GGeneProductENSBTAG00000002734 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8666
EIF3HGeneProductENSBTAG00000014032 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8667
EIF3IGeneProductENSBTAG00000014388 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8668
EIF3JGeneProductENSBTAG00000000359 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8669
EIF4A1GeneProductENSBTAG00000000132 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1973
EIF4A2GeneProductENSBTAG00000014724 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1974
EIF4BGeneProductENSBTAG00000006883 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1975
EIF4EBP1GeneProductENSBTAG00000027654 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1978
EIF4EBP2GeneProductENSBTAG00000019124 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1979
EIF4EBP3GeneProduct
EIF4EGeneProductENSBTAG00000009522 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1977
EIF4G1GeneProductENSBTAG00000012881 (Ensembl)
  • TrEMBL accession number O43177 refers to same protein.
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1981
EIF4G3GeneProductENSBTAG00000040215 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8672
EIF5AGeneProductENSBTAG00000002018 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1984
EIF5BGeneProductENSBTAG00000034255 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9669
EIF5GeneProductENSBTAG00000016282 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1983
EIF6GeneProductENSBTAG00000011263 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3692
ETF1GeneProductENSBTAG00000011415 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2107
GSPT2GeneProduct
PABPC1GeneProductENSBTAG00000046358 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:26986
PAIP1GeneProductENSBTAG00000046231 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10605
WBSCR1GeneProductENSBTAG00000047249 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7458

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP965"
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