Adipogenesis (Bos taurus)

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1Possible Lipodystrophy GenesPreadipocyteInsulin Action GenesGrowth Factors/HormonesAdipocyte Secretory ProductsTranscription Factors/ModulatorsDifferentiated adipocyteInhibitors of Preadipocyte to Adipocyte TransitionFully DifferentiatedAdipocyte MarkersMiscellaneous FactorsDDIT3E2F1E2F4NCOA2LPIN3SLC2A4NCOR1AGTHMGA1GH1TGFB1IRS3PFOXC2UCP1BMP3NR2F1RORACUGBP1CTNNB1NAMPTKLF15NCOA1ADPNKLF7WNT1SCDHIF1ALPIN1IL6STRBL1IL6BSCL2TWIST1STAT6SFRP4MIXL1STAT1PPARGFZD1CEBPBDFKLF6MEF2BMEF2DLIFMBNL1PCK2RBL2CISD1RARAHSLGADD45BTRIB3CEBPDAHRNRIP1SP1MEF2APRLRFRZBWNT10BRXRAPLINADIPOQSREBF1SOCS3CYP26A1PCK1SPOCK1IRS4WNT5BMIFGR-AINSBMP2EPAS1IRS1LIFRPPARDAGPAT2NDNCNTFRSTAT5BZMPSTE24GATA4OSMGATA2ASIPLPIN2SMAD3OBGDF10GADD45AHNF1ASERPINE1KLF5GTF3AID3CYP26B1LMNAPLIN2GATA3EBF1SOCS1STAT5ASTAT2PPARAEGR2RETNFOXO1CEBPABMP4PTGISLPLRB1STAT3IRS2MEF2CDLKCREB1PPARGC1ABMP1NR1H3DVL1TNFWWTR1CDKN1ANCOR2IGF-IFASRXRG


Description

The different classess of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, composed of white and brown adipose tissue, is composed of adipocytes. This pathway is primarily studied to understand factors that contribute to obesity and diabetes. Transcriptional and hormonal regulators of adipocyte formation are indicated.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP236(80209) with a 94.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Rosen ED, Spiegelman BM; ''Molecular regulation of adipogenesis.''; Annu Rev Cell Dev Biol, 2000 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
80782view15:25, 30 June 2015Mkutmonhomology conversion
79147view06:11, 5 March 2015KhanspersUpdated conversion from Hs
63401view00:07, 10 May 2013MaintBotUpdated to 2013 gpml schema
40575view19:32, 1 March 2011MaintBotRemoved redundant pathway information and comments
33813view00:22, 9 December 2009MaintBotAutomatic update of empty xrefs
30556view22:01, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ADIPOQGeneProductENSBTAG00000019813 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9370
ADPNGeneProductENSBTAG00000045746 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:80339
AGPAT2GeneProductENSBTAG00000025161 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10555
AGTGeneProductENSBTAG00000012393 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:183
AHRGeneProductENSBTAG00000007746 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:196
ASIPGeneProductENSBTAG00000034077 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:434
BMP1GeneProductENSBTAG00000000917 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:649
BMP2GeneProductENSBTAG00000005111 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:650
BMP3GeneProductENSBTAG00000017642 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:651
BMP4GeneProductENSBTAG00000003835 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:652
BSCL2GeneProductENSBTAG00000002503 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:26580
CDKN1AGeneProductENSBTAG00000008353 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1026
CEBPAGeneProduct
CEBPBGeneProduct
CEBPDGeneProduct
CISD1GeneProductENSBTAG00000003634 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:55847
CNTFRGeneProductENSBTAG00000015361 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1271
CREB1GeneProductENSBTAG00000005474 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1385
CTNNB1GeneProductENSBTAG00000016420 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1499
CUGBP1GeneProductENSBTAG00000002520 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10658
CYP26A1GeneProductENSBTAG00000021118 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1592
CYP26B1GeneProductENSBTAG00000012212 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:56603
DDIT3GeneProductENSBTAG00000031544 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1649
DFGeneProductENSBTAG00000046245 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1675
DLKGeneProductENSBTAG00000037899 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8788
DVL1GeneProductENSBTAG00000010696 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1855
E2F1GeneProductENSBTAG00000003971 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1869
E2F4GeneProductENSBTAG00000012063 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1874
EBF1GeneProductENSBTAG00000037508 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1879
EGR2GeneProductENSBTAG00000046409 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1959
EPAS1GeneProductENSBTAG00000003711 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2034
FASGeneProductENSBTAG00000010785 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:355
FOXC2GeneProductENSBTAG00000012465 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2303
FOXO1GeneProductENSBTAG00000044105 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2308
FRZBGeneProductENSBTAG00000010977 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2487
FZD1GeneProductENSBTAG00000002107 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8321
GADD45AGeneProductENSBTAG00000013860 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1647
GADD45BGeneProductENSBTAG00000025462 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4616
GATA2GeneProductENSBTAG00000019707 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2624
GATA3GeneProductENSBTAG00000017243 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2625
GATA4GeneProductENSBTAG00000005425 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2626
GDF10GeneProductENSBTAG00000001019 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2662
GH1GeneProductHomologyConvert: Multiple homologues found: En:ENSBTAG00000017220;En:ENSBTAG00000017220;
GR-AGeneProductENSBTAG00000019472 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2908
GTF3AGeneProductENSBTAG00000012600 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2971
HIF1AGeneProductENSBTAG00000020935 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3091
HMGA1GeneProductENSBTAG00000034529 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3159
HNF1AGeneProductENSBTAG00000021795 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6927
HSLGeneProductENSBTAG00000038321 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3991
ID3GeneProductENSBTAG00000030425 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3399
IGF-IGeneProductENSBTAG00000011082 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3479
IL6GeneProductENSBTAG00000014921 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3569
IL6STGeneProductENSBTAG00000017745 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3572
INSGeneProduct
IRS1GeneProductENSBTAG00000021308 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3667
IRS2GeneProductENSBTAG00000012019 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8660
IRS3PGeneProduct
IRS4GeneProductENSBTAG00000006535 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8471
KLF15GeneProductENSBTAG00000008313 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:28999
KLF5GeneProductENSBTAG00000002129 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:688
KLF6GeneProductENSBTAG00000015188 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1316
KLF7GeneProductENSBTAG00000044097 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8609
LIFGeneProductENSBTAG00000007424 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3976
LIFRGeneProductENSBTAG00000010423 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3977
LMNAGeneProductENSBTAG00000017574 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4000
LPIN1GeneProductENSBTAG00000007689 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:23175
LPIN2GeneProductENSBTAG00000012060 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9663
LPIN3GeneProductENSBTAG00000009165 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:64900
LPLGeneProductENSBTAG00000012855 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4023
MBNL1GeneProductENSBTAG00000004564 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4154
MEF2AGeneProductENSBTAG00000010649 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4205
MEF2BGeneProduct
MEF2CGeneProductENSBTAG00000020701 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4208
MEF2DGeneProductENSBTAG00000046545 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4209
MIFGeneProductENSBTAG00000007375 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4282
MIXL1GeneProductENSBTAG00000002139 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:83881
NAMPTGeneProductENSBTAG00000015509 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10135
NCOA1GeneProductENSBTAG00000015007 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8648
NCOA2GeneProductENSBTAG00000020312 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10499
NCOR1GeneProductENSBTAG00000013271 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9611
NCOR2GeneProductENSBTAG00000024603 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9612
NDNGeneProductENSBTAG00000002186 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4692
NR1H3GeneProductENSBTAG00000010681 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10062
NR2F1GeneProductENSBTAG00000017599 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7025
NRIP1GeneProductENSBTAG00000047293 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8204
OBGeneProductENSBTAG00000014911 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3952
OSMGeneProductENSBTAG00000016163 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5008
PCK1GeneProductENSBTAG00000001936 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5105
PCK2GeneProductENSBTAG00000011934 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5106
PLIN2GeneProductENSBTAG00000005718 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:123
PLINGeneProductENSBTAG00000015350 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5346
PPARAGeneProductENSBTAG00000008063 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5465
PPARDGeneProductENSBTAG00000017542 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5467
PPARGC1AGeneProductENSBTAG00000017024 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10891
PPARGGeneProductENSBTAG00000001333 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5468
PRLRGeneProductENSBTAG00000025035 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5618
PTGISGeneProductENSBTAG00000017537 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5740
RARAGeneProductENSBTAG00000012500 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5914
RB1GeneProductENSBTAG00000006640 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5925
RBL1GeneProductENSBTAG00000011541 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5933
RBL2GeneProductENSBTAG00000016243 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5934
RETNGeneProductENSBTAG00000004716 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:56729
RORAGeneProductENSBTAG00000015904 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6095
RXRAGeneProductENSBTAG00000017851 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6256
RXRGGeneProductENSBTAG00000016801 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6258
SCDGeneProductENSBTAG00000047957 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6319
SERPINE1GeneProductENSBTAG00000014465 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5054
SFRP4GeneProductENSBTAG00000015366 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6424
SLC2A4GeneProductENSBTAG00000009190 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6517
SMAD3GeneProductENSBTAG00000012599 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4088
SOCS1GeneProductENSBTAG00000004386 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8651
SOCS3GeneProductENSBTAG00000008441 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9021
SP1GeneProductENSBTAG00000003021 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6667
SPOCK1GeneProductENSBTAG00000003502 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6695
SREBF1GeneProductENSBTAG00000007884 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6720
STAT1GeneProductENSBTAG00000007867 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6772
STAT2GeneProductENSBTAG00000004380 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6773
STAT3GeneProductENSBTAG00000021523 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6774
STAT5AGeneProductENSBTAG00000009496 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6776
STAT5BGeneProductENSBTAG00000010125 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6777
STAT6GeneProductENSBTAG00000006335 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6778
TGFB1GeneProductENSBTAG00000020457 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7040
TNFGeneProductENSBTAG00000025471 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7124
TRIB3GeneProductENSBTAG00000017007 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:57761
TWIST1GeneProductENSBTAG00000046922 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7291
UCP1GeneProductENSBTAG00000004647 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7350
WNT10BGeneProductENSBTAG00000015347 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7480
WNT1GeneProductENSBTAG00000015364 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7471
WNT5BGeneProductENSBTAG00000001341 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:81029
WWTR1GeneProductENSBTAG00000007814 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:25937
ZMPSTE24GeneProductENSBTAG00000044178 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10269

Annotated Interactions

No annotated interactions
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