Glucose homeostasis (Homo sapiens)

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1Bile saltsGlucosevalinePyruvateOrnithineGCATyrosineLipolysisMalateProteolysisHypoxanthineGlycolysisCitrullineHistidineArginineTCDCAIsoleucineGCDCAGlycerolB-OH-butyrateInsulinLysineMethionineKetogenesisLactateHippuric acidPhenylalanine


Description

An organism-level overview of Glucose homeostasis. At this moment the focus is on metabolites that can be measured in the plasma, but it would be nice to show the interaction between the different organs (Adipose tissue, Liver, Intestine, Muscle) as well as the involvement of hormones other than insulin

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Quality Tags

Ontology Terms

 

Bibliography

  1. Shaham O, Wei R, Wang TJ, Ricciardi C, Lewis GD, Vasan RS, Carr SA, Thadhani R, Gerszten RE, Mootha VK; ''Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity.''; Mol Syst Biol, 2008 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
126226view06:24, 17 April 2023EgonwLicense is CCZero
117736view12:38, 22 May 2021EweitzModified title
111178view05:20, 22 July 2020EgonwMade another pathway clickable
106170view12:06, 16 August 2019MaintBotHMDB identifier normalization
88591view19:36, 11 August 2016Mkutmonfix unconnected lines
85023view20:18, 5 April 2016KhanspersQuick edit to datanode annotation or property
72077view20:27, 24 October 2013EgonwInsulin is not a metabolite.
63197view20:53, 8 May 2013MaintBotUpdating gpml version
45308view20:04, 7 October 2011AlexanderPicoOntology Term : 'glucose homeostasis pathway' added !
41231view23:46, 1 March 2011MaintBotRemoved redundant pathway information and comments
38930view21:40, 24 September 2010AlexanderPico
38929view21:39, 24 September 2010AlexanderPico
38928view21:38, 24 September 2010AlexanderPicopathway nodes
34501view23:06, 16 December 2009KhanspersAdded connector
28570view13:09, 13 February 2009MartijnVanIerselRemoved empty metabolite
28569view13:07, 13 February 2009MartijnVanIerselAdded literature
28568view13:04, 13 February 2009MartijnVanIerselModified categories
28567view13:04, 13 February 2009MartijnVanIerselModified description
28566view13:02, 13 February 2009MartijnVanIerselNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ArginineMetaboliteHMDB00517 (HMDB)
B-OH-butyrateMetaboliteHMDB00011 (HMDB)
CitrullineMetaboliteHMDB00904 (HMDB)
GCAMetaboliteHMDB00138 (HMDB)
GCDCAMetaboliteHMDB00637 (HMDB)
GlucoseMetaboliteHMDB00122 (HMDB)
GlycerolMetaboliteHMDB00131 (HMDB)
GlycolysisPathwayWP534 (WikiPathways)
Hippuric acidMetaboliteHMDB00714 (HMDB)
HistidineMetaboliteHMDB00177 (HMDB)
HypoxanthineMetaboliteHMDB00157 (HMDB)
InsulinGeneProductENSG00000254647 (Ensembl)
IsoleucineMetaboliteHMDB00172 (HMDB)
KetogenesisPathway
LactateMetaboliteHMDB00190 (HMDB)
LipolysisPathway
LysineMetaboliteHMDB00182 (HMDB)
MalateMetaboliteHMDB00156 (HMDB)
MethionineMetaboliteHMDB00696 (HMDB)
OrnithineMetaboliteHMDB00214 (HMDB)
PhenylalanineMetaboliteHMDB00159 (HMDB)
ProteolysisPathway
PyruvateMetaboliteHMDB00243 (HMDB)
TCDCAMetaboliteHMDB00951 (HMDB)
TyrosineMetaboliteHMDB00158 (HMDB)
valineMetaboliteHMDB00883 (HMDB)

Annotated Interactions

No annotated interactions

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