Type III interferon signaling (Bos taurus)

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ISREISGF3 complexTYK2IL28BJAK1IFNLR1STAT2IRF9STAT1IL10RBIFNL1IL28AGASSTAT1STAT1


Description

The recently identified type III interferon group consists of three IFN-λ (lambda) genes encoding molecules called IFN-λ1, IFN-λ2 and IFN-λ3 (also called IL29, IL28A and IL28B respectively). These IFNs signal through a receptor complex consisting of IL10R2 (also called CRF2-4) and IFNLR1 (also called CRF2-12).

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP2113(70107) with a 75.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
86896view07:57, 14 July 2016MkutmonOntology Term : 'interleukin-28A signaling pathway' added !
86895view07:56, 14 July 2016MkutmonOntology Term : 'interleukin-29 signaling pathway' added !
86894view07:56, 14 July 2016MkutmonOntology Term : 'Jak-Stat signaling pathway' added !
86893view07:56, 14 July 2016MkutmonOntology Term : 'interleukin-28B signaling pathway' added !
86892view07:56, 14 July 2016Mkutmonfixed ontology tag issue
80749view15:24, 30 June 2015MkutmonNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
IFNL1GeneProductENSBTAG00000047691 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:282618
IFNLR1GeneProductENSBTAG00000001101 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:163702
IL10RBGeneProductENSBTAG00000019404 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3588
IL28AGeneProduct
IL28BGeneProduct
IRF9GeneProductHomologyConvert: Multiple homologues found: En:ENSBTAG00000005816;En:ENSBTAG00000005815;
JAK1GeneProductENSBTAG00000003147 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3716
STAT1GeneProductENSBTAG00000007867 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6772
STAT2GeneProductENSBTAG00000004380 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6773
TYK2GeneProductENSBTAG00000011698 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7297

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP3173"
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