Prostaglandin synthesis and regulation (Pan troglodytes)
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Gq signaling
pathway
Inactive Metabolites
Cell Membrane
Phospholipids
prolactin
release
Cytoplasm
PG Synthases
Cortisone
Arachidonic Acid
ANXA2
PTGDS
ANXA1
Cortisol
PTGIR
PTGFR
LOC457306
PTGS2
PGE2
ANXA3
PTGIS
Calcium
HPGD
PTGER3
TXA2
Prostaglandin H2
EDN1
PGF2a
Cortisol
PGI2
PLA2G4A
PTGER1
Calcium
ANXA6
EDNRA
HSD11B1
TBXAS1
PTGS1
ANXA8
PTGER2
LOC748998
HSD11B2
ANXA4
PGF2a
PTGDR
PRL
ANXA5
EDNRB
S100A6
PTGER4
Progesterone
SCGB1A1
Description
No description
Comments
GenMAPP notes
Adapted from Gross, G et al. 2000, Society for Gynecologic Investigation; 7:88-95
GenMAPP remarks
See note for more details
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP98(r20887)
with a 80% conversion rate.
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Quality Tags
Ontology Terms
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Bibliography
No bibliography
History
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Compare
Revision
Action
Time
User
Comment
118054
view
10:36, 24 May 2021
Eweitz
Modified title
106923
view
13:39, 17 September 2019
MaintBot
HMDB identifier normalization
87611
view
08:54, 25 July 2016
Lindarieswijk
Ontology Term : 'prostaglandin biosynthetic pathway' added !
87610
view
08:54, 25 July 2016
Lindarieswijk
Ontology Term : 'prostaglandin signaling pathway' added !
71657
view
19:39, 17 October 2013
MaintBot
Automated update of data sources
69222
view
18:33, 8 July 2013
MaintBot
Updated to 2013 gpml schema
41525
view
01:57, 2 March 2011
MaintBot
Removed redundant pathway information and comments
34263
view
21:51, 9 December 2009
MaintBot
Automatic update of empty xrefs
33541
view
09:37, 1 December 2009
MaintBot
Removed group label
31572
view
21:59, 13 August 2009
MaintBot
Fixed text labels
30446
view
21:24, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
ANXA1
GeneProduct
472953 (Entrez Gene)
ANXA2
GeneProduct
747018 (Entrez Gene)
ANXA3
GeneProduct
737760 (Entrez Gene)
ANXA4
GeneProduct
459542 (Entrez Gene)
ANXA5
GeneProduct
461466 (Entrez Gene)
ANXA6
GeneProduct
462198 (Entrez Gene)
ANXA8
GeneProduct
Arachidonic Acid
Metabolite
Calcium
Metabolite
HMDB00464 (HMDB)
Cortisol
Metabolite
EDN1
GeneProduct
462437 (Entrez Gene)
PMID: 1474344
EDNRA
GeneProduct
461530 (Entrez Gene)
EDNRB
GeneProduct
452613 (Entrez Gene)
HPGD
GeneProduct
461613 (Entrez Gene)
HSD11B1
GeneProduct
457698 (Entrez Gene)
HSD11B2
GeneProduct
468001 (Entrez Gene)
LOC457306
GeneProduct
457306 (Entrez Gene)
PMID: 12962548 relationship with Annexin 2
LOC748998
GeneProduct
748998 (Entrez Gene)
PGE2
Metabolite
HMDB03175 (HMDB)
PGF2a
Metabolite
HMDB01139 (HMDB)
PGI2
Metabolite
HMDB01335 (HMDB)
PLA2G4A
GeneProduct
469617 (Entrez Gene)
PRL
GeneProduct
462468 (Entrez Gene)
PTGDR
GeneProduct
452906 (Entrez Gene)
PTGDS
GeneProduct
749402 (Entrez Gene)
PTGER1
GeneProduct
747643 (Entrez Gene)
PTGER2
GeneProduct
467459 (Entrez Gene)
PTGER3
GeneProduct
456940 (Entrez Gene)
PTGER4
GeneProduct
450195 (Entrez Gene)
PTGFR
GeneProduct
456970 (Entrez Gene)
PTGIR
GeneProduct
PTGIS
GeneProduct
458323 (Entrez Gene)
PTGS1
GeneProduct
464713 (Entrez Gene)
PTGS2
GeneProduct
469616 (Entrez Gene)
Progesterone
Metabolite
Prostaglandin H2
Metabolite
S100A6
GeneProduct
738116 (Entrez Gene)
SCGB1A1
GeneProduct
466634 (Entrez Gene)
PMID: 7615804, PMID: 3292559
TBXAS1
GeneProduct
463774 (Entrez Gene)
TXA2
Metabolite
HMDB01452 (HMDB)
Annotated Interactions
No annotated interactions
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Discussion
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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No annotated interactions