G13 signaling pathway (Gallus gallus)

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1GCytokinesis13Activated Rho AStress FiberDisappearanceDisassembly of ActinActin PolymerizationActin ReorganizationCell-Cell AdhesionMembrane RufflingActin PolymerizationFilopodia FormationContraction & Actin-MyosinInteraction, Focal AdhesionStress Fiber ContractionAnti-ApoptoticCYFIP1SH3RF1RHOAPIK3CALIMK1GNA13PIK3CDROCK1ARHGDIBPFN1PIK3CBDIAPH1PKN1PPP1CBIQGAP1PIK3R2IQGAP2ARHGDIGROCK2MYBPHMAP3K4CALMRHPN2CDC42PIP4K2ACFL1CITMYL1ARHGEF1cRac1ARPS6KB1CFL2WASPAK3WASLMAPK10RTKNTNK2


Description

The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells. Source: Wikipedia

Comments

HomologyMapper 
This pathway was inferred from Homo sapiens pathway WP524 (r95116) with a 84.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Neves SR, Ram PT, Iyengar R; ''G protein pathways.''; Science, 2002 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
117199view10:33, 18 May 2021EweitzModified title
95755view14:07, 19 January 2018MkutmonHomology conversion update
72065view17:31, 24 October 2013MaintBotremoved data source from nodes without identifier
72013view12:24, 24 October 2013Mkutmonfixed connected lines
68853view17:20, 8 July 2013MaintBotUpdated to 2013 gpml schema
67278view10:30, 26 June 2013Christine ChichesterOntology Term : 'G protein mediated signaling pathway via Galpha12/Galpha13 family' added !
62675view18:31, 1 May 2013MaintBotUpdated Ensembl and UniProt data source
40991view22:55, 1 March 2011MaintBotRemoved redundant pathway information and comments
35417view10:36, 12 February 2010ThomasModified description
35416view10:35, 12 February 2010Thomasremoved braces, fixed labels, added literature
33913view18:04, 9 December 2009MaintBotAutomatic update of empty xrefs
33497view15:12, 30 November 2009MaintBotRemoved group label
32476view17:36, 15 August 2009MaintBotFixed text labels
31543view21:49, 13 August 2009MaintBotFixed text labels
30395view21:07, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ARHGDIBGeneProductENSGALG00000011738 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:397
ARHGDIGGeneProductENSGALG00000036819 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:398
ARHGEF1GeneProductNo homologues found for original id L:9138
CALMGeneProductENSGALG00000026445 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:801
CDC42GeneProductENSGALG00000004796 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:998
CFL1GeneProductNo homologues found for original id L:1072
CFL2GeneProductENSGALG00000010027 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:1073
CITGeneProductENSGALG00000007354 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:11113
CYFIP1GeneProductENSGALG00000016736 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:23191
DIAPH1GeneProductNo homologues found for original id L:1729
GNA13GeneProductENSGALG00000036028 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10672
IQGAP1GeneProductENSGALG00000030162 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:8826
IQGAP2GeneProductENSGALG00000043276 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10788
LIMK1GeneProductENSGALG00000001076 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:3984
MAP3K4GeneProductENSGALG00000020003 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:4216
MAPK10GeneProductENSGALG00000011109 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5602
MYBPHGeneProductENSGALG00000000164 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:4608
MYL1GeneProductENSGALG00000002907 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:4632
PAK3GeneProductENSGALG00000008058 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5063
PFN1GeneProductNo homologues found for original id L:5216
PIK3CAGeneProductENSGALG00000008934 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5290
PIK3CBGeneProductENSGALG00000005505 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5291
PIK3CDGeneProductENSGALG00000002583 (Ensembl)
  • P42338
  • Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5293
PIK3R2GeneProductENSGALG00000003428 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5296
PIP4K2AGeneProductENSGALG00000007877 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5305
PKN1GeneProductNo homologues found for original id L:5585
PPP1CBGeneProductENSGALG00000010026 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5500
RHOAGeneProductENSGALG00000003806 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:387
RHPN2GeneProductENSGALG00000004814 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:85415
ROCK1GeneProductENSGALG00000014922 (Ensembl)
  • S69211
  • Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6093
ROCK2GeneProductENSGALG00000016451 (Ensembl)
  • BAA31594
  • Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:9475
RPS6KB1GeneProductENSGALG00000005198 (Ensembl)
  • A41687
  • Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6198
RTKNGeneProductENSGALG00000043620 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6242
SH3RF1GeneProductENSGALG00000009692 (Ensembl)
  • Posh
  • Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:57630
TNK2GeneProductENSGALG00000027983 (Ensembl)
  • S33596
  • Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10188
WASGeneProductNo homologues found for original id L:7454
WASLGeneProductENSGALG00000008797 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:8976
cRac1AGeneProductENSGALG00000007130 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5879

Annotated Interactions

No annotated interactions
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