Melanogenesis (Homo sapiens)
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Description
Melanogenesis is the process by which melanocytes produce melanin, a pigment found in the skin, eyes, and hair. Melanogenesis leads to a long-lasting pigmentation, which is in contrast to the pigmentation that originates from oxidation of already-existing melanin.
Cutaneous melanin pigment plays a critical role in camouflage, mimicry, social communication, and protection against harmful effects of solar radiation. Melanogenesis is under complex regulatory control by multiple agents.
Description adapted from Wikipedia and KEGG.Quality Tags
Ontology Terms
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DataNodes
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| Name | Type | Database reference | Comment |
|---|---|---|---|
| Active TGF-B | Protein | ||
| Active VEGF | Protein | ||
| ET-1 | Protein | ||
| Estrogen | Protein | ||
| MITF | Protein | ||
| Melanogenesis | Pathway | ||
| PAI-1 | Protein | ||
| Plasmin | Metabolite | CHEBI:53373 (ChEBI)  | |
| Plasminogen | Protein | P00747 (Uniprot-TrEMBL) | |
| SCF | Protein | ||
| Tranexamic Acid | Protein | ||
| tPA | Protein |
Annotated Interactions
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