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1. Yes it's automatically generated. You can delete the curation tag at any time, if you feel you've addressed as many of the issues as possible. Note that our bots apply new tags after every edit, so if you're planning more edits, wait until you're done to delete the tag. 2. Up to you whether you use "geneProduct" or "protein". Both are accurate. 3. "catalysis" is appropriate. The system does not have a preference, per se, it has an alias database with gene and protein IDs. You can choose whichever you find most effective. Downstream analysis tools should offer ways to convert/unify if necessary. 4. You can not annotate a datanode with 2 IDs. You can add the terms you've looked up as a comment on the node, but only 1 ID is accepted for mapping. And I recommend using the one in the database so we can support linkouts and ID mapping, etc.
Thank you for the answers. I tried now to annotate the geneproducts with the appropriate UniProt ID, but then in the "live" version it says that "Unable to load external references.", despite that this does work when I am the "editing mode". If I use the Entrez Gene IDs to annotate a protein then the external references can be loaded. A similar thing happens for metabolites, where HMDB IDs seem to work best. The curation tag "This pathway contains genes, proteins or metabolites with missing database annotations'" now only "complains" about the references to the other pathways andnd about the metabolite H+ and ubiquinol-10. I do not know why and how to correct this.
Use the ID you think is best. The "unable to load external refs" sounds like a bug on our end. If you found it in the database and it produces external references in edit mode, then you're all set. As for the curation tag, the "correction" is to simply remove it. Just click the little red 'x' after you're done making your edits. It won't appear again until it's triggered by future edits.
The pathway is final for now and the paper submitted. I picked the Entrez Gene IDs as we needed to submit the paper and the UniProt IDs did not generate links to other databases in the live version, only in the edit mode. I would prefer UniProt IDs though as it are enzymes and not genes, so if there is a fix let me know.
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