View source
From WikiPathways
Start a new discussionNRP2 seems to bind to a Spike derived peptide after "protease activity at the furin site" (1)
There have been no changes to this discussion for at least 30 days. If it is concluded, you may want to write a summary.
Although Furin and TMPRSS2 peptidase lead to different peptides that are a few amino acids different both are described as "furin cleavage sites" in some papers I saw. So maybe the paper about NRP1 should not be read as FURIN specific.
Catalysis reaction is not attached to FURIN (1)
There have been no changes to this discussion for at least 30 days. If it is concluded, you may want to write a summary.
The end of catalysis reaction is not attached to FURIN (left top corner of human cell). This reaction is not displayed in MINERVA due to this.
Incorrect molecule types (1)
There have been no changes to this discussion for at least 30 days. If it is concluded, you may want to write a summary.
In the diagram, ACE2 and TMPRSS2 should be typed as "Protein", now are typed as "Gene product"
You do not have permission to edit pages, for the following reason:
You can view and copy the source of this page:
Return to Pathway Talk:WP4846.
