Thread:Difficult pathway (1)
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The original pathway figure is difficult to interpret. Based on the figure legend, HMR should probably be represented as an enzyme (maybe with a dashed line to indicate that the process is not described), for the two interactions:
Phytochromes - PIFs
and
Phytochromes - DET1
So you need to add an anchor to those lines and then add the interaction going from HMR to the anchor. Also this means that the interactions going from CUL4 complexes and CSN to HMR need to be removed. Instead there should be only one inhibition going from all three complexes to Phytochromes.