Thread:Location of DDC (1)

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Revision as of 21:17, 10 April 2011.
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What is the evidence that dopa decarboxylase is inside synaptic vesicles? --JWSchmidt 13:23, 7 April 2011 (UTC)

There is none, as far as I can tell. In fact, SLC18A2 transports dopamine, not dopa, into vesicles, so the DDC reaction should be represented outside the vesicle. I've updated the pathway and added a reference. Nice catch!

AlexanderPico 21:17, 10 April 2011 (UTC)

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