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- Pathway:WP1533 ... TLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">cDNA cloning of mouse and human cholesterol 25-hydroxylases, polytopic membrane proteins that sy ... ... tion of the GGPS1 genes encoding geranylgeranyl diphosphate synthases from mouse and human.</bp:TITLE>546 KB (68191 words) - 11:47, 2 August 2024
- Pathway:WP1763 ... to give an overview of specific mechanisms associated with pluripotency in mouse. Each node represents a gene and its corresponding protein product. As sta ... ... rk: An Electronic Representation of the Network Underlying Pluripotency in Mouse, and Its Applications. PLoS ONE 5(12): e15165. doi:10.1371/journal.pone.00 ...741 KB (73570 words) - 19:29, 26 April 2023
- Pathway:WP1775 ... the S. pombe rad17 protein. Targeted deletion of the N-terminal region of mouse Rad17 leads to embryonic lethality, strongly suggesting that human Rad17 i ... ... the S. pombe rad17 protein. Targeted deletion of the N-terminal region of mouse Rad17 leads to embryonic lethality, strongly suggesting that human Rad17 i ...618 KB (67890 words) - 12:00, 22 May 2021
- Pathway:WP1780 ... rotein complex mediate ATP-dependent sterol export (Wang et al. 2006). The mouse proteins localize to the apical plasma membranes of enterocytes and hepato ...297 KB (32746 words) - 11:32, 1 November 2018
- Pathway:WP1784 ... ase-3 was found to be responsible for TJP1 (ZO-1) cleavage in both dog and mouse cells (Chin et al. 2006, Zehendner et al. 2011).</Comment>247 KB (26670 words) - 16:34, 25 January 2021
- Pathway:WP2747 ... tion and enzymatic activity have been inferrred from the properties of its mouse homologue (Kienesberger et al. 2008).</Comment> ... uman enzyme (Li et al. 2003; Zaccheo et al. 2004). Additional studies in a mouse system indicate that enzyme abundance and activity are regulated by osmoti ...535 KB (60131 words) - 16:48, 25 January 2021
- Pathway:WP1788 ... can be activated by bile acids and their salts, its physiological ligands. Mouse Nrih4 is highly expressed in the liver, intestine, kidney and adrenal glan ... ... al assignment of the sterol 12alpha-hydroxylase gene (CYP8B1) in human and mouse: eukaryotic cytochrome P-450 gene devoid of introns.</bp:TITLE>490 KB (51496 words) - 16:47, 25 January 2021
- Pathway:WP2797 <Comment Source="Reactome">As inferred from mouse, FABP1 localizes to the nucleus where it may deliver lipids to PPARA.</Com ... <Comment Source="Reactome">As inferred from mouse, FABP1 localizes to the nucleus where it may deliver lipids to PPARA.</Com ...242 KB (26081 words) - 16:58, 25 January 2021
- Pathway:WP2741 ... r cloning, expression, and characterization of myo-inositol oxygenase from mouse, rat, and human kidney.</bp:TITLE> ... histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19.</bp:TITLE>342 KB (36191 words) - 16:49, 25 January 2021
- Pathway:WP2740 ... AGPAT5, are inferred to have such activity based on studies of homologous mouse enzymes (Lu et al. 2005). These enzymes differ in their tissue specific p ... ... y mediate PC exchange at cellular membranes (Roderick et al. 2002). Recent mouse studies reveals a key regulatory role for PCTP in lipid and glucose metabo ...783 KB (85563 words) - 16:56, 25 January 2021
- Pathway:WP3399 ... 2013). The preference of NEIL3 for ssDNA was structurally explained using mouse Neil3 (Liu et al. 2013).</Comment> ... ://www.w3.org/2001/XMLSchema#string">Expression and purification of active mouse and human NEIL3 proteins.</bp:TITLE>373 KB (40249 words) - 16:21, 25 January 2021
- Pathway:WP2777 ... et al. 2009, Treebak et al. 2009, Koumanov et al. 2011). As inferred from mouse, binding to 14-3-3 does not interfere with the interaction between AS160 a ... <Comment Source="Reactome">As inferred from mouse, AKT2 (PKB-beta) phosphorylates RBC2 (RALGAPA2) on serine-486, serine-696, ...144 KB (15833 words) - 17:03, 25 January 2021
- Pathway:WP1795 ... ma#string">Mutations in a delta 8-delta 7 sterol isomerase in the tattered mouse and X-linked dominant chondrodysplasia punctata. [email protected].</bp:T ...184 KB (19677 words) - 16:11, 25 January 2021
- Pathway:WP1797 <Comment Source="Reactome">As inferred from mouse, BMAL1:CLOCK (ARNTL:CLOCK) and BMAL1:NPAS2 (ARNTL:NPAS2) heterodimers bind ... <Comment Source="Reactome">As inferred from mouse, PER proteins can form homodimers and CRY proteins can form heterodimers w ...245 KB (27124 words) - 17:04, 25 January 2021
- Pathway:WP1803 <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesi ... ... Schema#string">Proteomic identification of proteins conjugated to ISG15 in mouse and human cells.</bp:TITLE>637 KB (67998 words) - 17:04, 25 January 2021
- Pathway:WP1809 ... er than Rap (Kawasaki et al. 1998, Ebinu et al. 1998).<br> <br>Mouse platelets that lack CalDAG-GEFI are severely compromised in integrin-depen ...67 KB (7535 words) - 16:07, 25 January 2021
- Pathway:WP1815 ... outer membrane fusion. Mammals have two mitofusins; Mfn1-null or Mfn2-null mouse embryonic fibroblast cells show predominantly fragmented mitochondria and ... ... TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Regulation of mouse steroidogenesis by WHISTLE and JMJD1C through histone methylation balance. ...224 KB (24483 words) - 16:20, 25 January 2021
- Pathway:WP1822 ... . 2005, Alvarez-Saavedra 2007, Van Esch et al. 2012). The phenotype of the mouse model of the MECP2 duplication syndrome in adult mice is reversible when M ... ... inflammatory responses (Dominguez-Soto et al. 2005). RUNX3 is involved in mouse TGF-beta-mediated dendritic cell function and its deficiency is linked to ...726 KB (85515 words) - 12:37, 22 May 2021
- Pathway:WP1826 ... The same group also reported that PP2 does not inhibit phosphorylation of mouse Clec1b by rhodocytin, in contrast to the reported effect in human platelet ... ... Vav family proteins are involved in filopodia and lamellipodia formation; mouse platelets deficient in Vav1 and Vav3 exhibit reduced filopodia and lamelli ...165 KB (18468 words) - 16:12, 25 January 2021
- Pathway:WP1829 ... une arthritis. Correspondingly, anti-PILRa mAb ameliorated inflammation in mouse arthritis models and suppressed the production of proinflammatory cytokine ... ... and, but the binding affinity of PILRB is much lower (Tabata et al. 2008). Mouse NK cells expressing PILRB mediate cytotoxicity against CD99-positive targe ...607 KB (68800 words) - 12:54, 22 May 2021
