DNA mismatch repair (Homo sapiens)

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Revision as of 17:04, 20 December 2018 by Khanspers (Talk | contribs)

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Description

DNA mismatch repair is a system for recognizing and repairing erroneous insertion, deletion and mis-incorporation of bases that can arise during DNA replication and recombination, as well as repairing some forms of DNA damage Source: wikipedia.

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Quality Tags

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Ontology Terms

Pathway Ontology : nervous system drug pathway

Bibliography

Hsieh P, Zhang Y; ''The Devil is in the details for DNA mismatch repair.''; Proc Natl Acad Sci U S A, 2017 PubMed Europe PMC Scholia
Iyer RR, Pluciennik A, Burdett V, Modrich PL; ''DNA mismatch repair: functions and mechanisms.''; Chem Rev, 2006 PubMed Europe PMC Scholia

History

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Revision	Action	Time	User	Comment
137038	view	21:23, 26 February 2025	Khanspers	Modified description
136385	view	01:36, 1 February 2025	Khanspers	interactions
136384	view	01:34, 1 February 2025	Khanspers	Modified description
117702	view	12:23, 22 May 2021	Eweitz	Modified title
113644	view	18:17, 9 November 2020	Egonw	Replaced old HMDB identifiers.
110621	view	18:03, 21 May 2020	Khanspers	clearer diagram
110620	view	17:13, 21 May 2020	Khanspers	Modified description
110610	view	05:39, 21 May 2020	Khanspers	Added more 3' MMR
110609	view	00:11, 21 May 2020	Khanspers	added 3' MMR
110608	view	00:04, 21 May 2020	Khanspers	work in progress
110607	view	23:35, 20 May 2020	Khanspers	work in progress
110606	view	23:15, 20 May 2020	Khanspers	work in progress
108607	view	05:19, 10 January 2020	Khanspers	fixed ordering
108606	view	05:18, 10 January 2020	Khanspers	Modified description
108605	view	05:12, 10 January 2020	Khanspers	Ontology Term : 'mismatch repair pathway' added !
108604	view	05:12, 10 January 2020	Khanspers	Ontology Term : 'DNA repair pathway' added !
108603	view	05:11, 10 January 2020	Khanspers	clarified complexes
108602	view	03:32, 10 January 2020	Khanspers	overhaul
108598	view	23:56, 9 January 2020	Khanspers	updated layout, style etc
106649	view	21:11, 12 September 2019	Khanspers	fixed interaction
106648	view	21:09, 12 September 2019	Khanspers	Modified description
105502	view	05:55, 8 August 2019	Khanspers	Modified description
102350	view	17:05, 20 December 2018	Khanspers	Modified title
102349	view	17:05, 20 December 2018	Khanspers	Modified title
102348	view	17:04, 20 December 2018	Khanspers	converted interactions to graphical lines
69021	view	17:49, 8 July 2013	MaintBot	Updated to 2013 gpml schema
59206	view	19:50, 22 February 2013	MaintBot	Updated Ensembl and UniProt data source
41198	view	23:43, 1 March 2011	MaintBot	Removed redundant pathway information and comments
36296	view	23:21, 17 March 2010	Khanspers	Modified categories
35172	view	14:57, 11 February 2010	Thomas	added literature ref
35171	view	14:54, 11 February 2010	Thomas	color fix
35170	view	14:53, 11 February 2010	Thomas	Modified description
35169	view	14:52, 11 February 2010	Thomas	solid shapes
29611	view	12:09, 23 May 2009	MartijnVanIersel	Updated ensembl references
21796	view	11:32, 14 November 2008	MaintBot	[[Pathway:Homo sapiens:Mismatch repair]] moved to [[Pathway:WP531]]: Moved to stable identifier
20396	view	21:16, 3 November 2008	AlexanderPico	fixed species info
10357	view	03:01, 23 January 2008	AlexanderPico	Modified categories
9590	view	10:51, 9 January 2008	Thomas	added mismatch repair pathway

External references

DataNodes

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Name	Type	Database reference
EXO1	GeneProduct	ENSG00000174371 (Ensembl)
LIG1	GeneProduct	ENSG00000105486 (Ensembl)
MLH1	GeneProduct	ENSG00000076242 (Ensembl)
MSH2	GeneProduct	ENSG00000095002 (Ensembl)
MSH6	GeneProduct	ENSG00000116062 (Ensembl)
PCNA	GeneProduct	ENSG00000132646 (Ensembl)
POLD1	GeneProduct	ENSG00000062822 (Ensembl)
RFC1	GeneProduct	ENSG00000035928 (Ensembl)
RPA1	GeneProduct	ENSG00000132383 (Ensembl)