Signal transduction through IL1R (Homo sapiens)

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DNAPIRAK1IL1RNNFKB1TAB1MAPK8NFKBIAJUNTGFB1MAP3K14TOLLIPIKBKBTRAF6MYD88MAPK14TNFIRAK3MAP3K7CHUKTGFB3TGFB2MAP3K1MAP2K6IFNA1IFNB1IRAK2ECSITMAP2K3RELAIL6IL1RAPIL1R1IL1AIL1BIL1RAPIL1R1IL1AIL1BMAP3K1NFKB1NFKBIARELAJUNPIKBKBP


Description

Signal transduction through IL1R.

Pathway based on Biocarta pathway (M12095).

https://cgap.nci.nih.gov/Pathways/BioCarta/h_il1rPathway

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Quality Tags

Ontology Terms

 

Bibliography

  1. Cargnello M, Roux PP; ''Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases.''; Microbiol Mol Biol Rev, 2011 PubMed Europe PMC Scholia
  2. O'Neill LA, Greene C; ''Signal transduction pathways activated by the IL-1 receptor family: ancient signaling machinery in mammals, insects, and plants.''; J Leukoc Biol, 1998 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
134761view00:18, 27 July 2024EweitzEconomize layout
134760view00:17, 27 July 2024EweitzUpgrade stacked nodes to groups, update connections accordingly
134759view00:14, 27 July 2024EweitzUpgrade state representation for phosphorylation
134758view00:10, 27 July 2024EweitzEconomize layout
134757view00:06, 27 July 2024EweitzOntology Term : 'immune response pathway' added !
102693view15:43, 19 January 2019FehrhartOntology Term : 'signaling pathway' added !
102663view12:48, 16 January 2019LaurentModified description
102656view10:04, 16 January 2019LaurentAdded references
102647view09:01, 16 January 2019LaurentFixed interactions
102622view15:10, 14 January 2019LaurentNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
CHUKGeneProduct1147 (Entrez Gene)
ECSITGeneProduct51295 (Entrez Gene)
IFNA1GeneProduct3439 (Entrez Gene)
IFNB1GeneProduct3456 (Entrez Gene)
IKBKBGeneProduct3551 (Entrez Gene)
IL1AGeneProduct3552 (Entrez Gene)
IL1BGeneProduct3553 (Entrez Gene)
IL1R1GeneProduct3554 (Entrez Gene)
IL1RAPGeneProduct3556 (Entrez Gene)
IL1RNGeneProduct3557 (Entrez Gene)
IL6GeneProduct3569 (Entrez Gene)
IRAK1GeneProduct3654 (Entrez Gene)
IRAK2GeneProduct3656 (Entrez Gene)
IRAK3GeneProduct11213 (Entrez Gene)
JUNGeneProduct3725 (Entrez Gene)
MAP2K3GeneProduct5606 (Entrez Gene)
MAP2K6GeneProduct5608 (Entrez Gene)
MAP3K1GeneProduct4214 (Entrez Gene)
MAP3K14GeneProduct9020 (Entrez Gene)
MAP3K7GeneProduct6885 (Entrez Gene)
MAPK14GeneProduct1432 (Entrez Gene)
MAPK8GeneProduct5599 (Entrez Gene)
MYD88GeneProduct4615 (Entrez Gene)
NFKB1GeneProduct4790 (Entrez Gene)
NFKBIAGeneProduct4792 (Entrez Gene)
RELAGeneProduct5970 (Entrez Gene)
TAB1GeneProduct10454 (Entrez Gene)
TGFB1GeneProduct7040 (Entrez Gene)
TGFB2GeneProduct7042 (Entrez Gene)
TGFB3GeneProduct7043 (Entrez Gene)
TNFGeneProduct7124 (Entrez Gene)
TOLLIPGeneProduct54472 (Entrez Gene)
TRAF6GeneProduct7189 (Entrez Gene)

Annotated Interactions

No annotated interactions

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