Leukocyte-intrinsic Hippo pathway functions (Homo sapiens)

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1IntracellularVesicleLeukocyteMyosin IIaIntegrin trafficking and distribution1/2 items only got the one for "1", e.g., MST1/2 and LATS1/2YAP/TAZ only got TAZHard to map from 14-3-3 on fig to YWHAQ hereI think pre-positioning DataNodes would be helpfulAlphabetical?YWHAQCD8ATERF2IPRASSF5CXCL10KNSTRNLPLYY1AP1CD8BLymphocyte motility, migration,thymic egressFOXO6TAZFOXP3RAB2AMST1CCR7KLF6BCRFOXO1KCNMA1DR1YAPFYB1CD4FOXO4APCSRAB13LATS1PRDM1FOXO3RHOASTK3PYWHAQPPTAZYAPPPTAZLATS1LATS2PPMOB1PMST1MST2PPSAV1PMOB1PNDR1PNDR2PMST1MST2FOXO6PFOXO4FOXO1PFOXO3PPFOXP3AcFOXP3TEADMST1MST2LPLPLFA-1LFA-1LFA-1LFA-1LFA-1LFA-1MST1MST2RAPRAPLRac1RAPRAPLRac1Kindlin-3Kindlin-3SKAPADAPMST1MST2RAB13Blimp1T.reg PhenotypeLFA-1RAB13RAP1RAPLSKAPRAP1RAPLLFA-1RHOACCR7Lymphocyte polarizationEnhanced BCR humoral responsein B lymphocytesCD19BLIMP1Terminal differentiation/clonalexpansion of CD8+ T cellsMaturation/survival ofT cells in SLORHOAFOXO6FOXO4FOXO1FOXO3Homeostatic maintenanceNORE1BFOXO6FOXO4FOXO1FOXO3miR-21LATS1Cytoarchitecturalintegrity/specificityLFA-1LPLT.h17/T.reg differentiationof CD4+ T cellsFOXO1FOXO3FOXP3p38MAPKAntigen cross presentationby APCsKindlin-3LFA-1Lymphocyte adhesionand extravasationRHOAintegrinsLFA-1


Description

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Bibliography

  1. Taha Z, Janse van Rensburg HJ, Yang X; ''The Hippo Pathway: Immunity and Cancer.''; Cancers (Basel), 2018 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
120673view01:29, 23 December 2021EweitzModified title
104788view23:55, 14 June 2019AriuttaOntology Term : 'immune response pathway' added !
104787view23:53, 14 June 2019AriuttaOntology Term : 'cancer' added !
104786view23:47, 14 June 2019AriuttaOntology Term : 'T cell' added !
104785view23:45, 14 June 2019AriuttaAdd upregulation interactions
104784view23:03, 14 June 2019AriuttaModified description
104783view22:48, 14 June 2019AriuttaAdd a couple more identifiers.
104780view22:46, 14 June 2019AriuttaAdd edge and more identifiers. Improve layout.
104334view14:05, 17 May 2019FehrhartOntology Term : 'leukocyte' added !
103581view16:16, 18 March 2019Elisson nlGene fixed
103433view09:39, 1 March 2019Marvin M2Ontology Term : 'Hippo signaling pathway' added !
103412view17:03, 27 February 2019AriuttaNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ADAPGeneProduct
APCSGeneProduct325 (Entrez Gene) APCs
BCRGeneProduct613 (Entrez Gene) BCR
BLIMP1GeneProduct
Blimp1GeneProduct
CCR7GeneProduct1236 (Entrez Gene) CCR7)
CD19GeneProduct
CD4GeneProduct920 (Entrez Gene) CD4+
CD8AGeneProduct925 (Entrez Gene) CD8+
CD8BGeneProduct926 (Entrez Gene) CD8+
CXCL10GeneProduct3627 (Entrez Gene) MOB1
DR1GeneProduct1810 (Entrez Gene) DR1
FOXO1GeneProduct2308 (Entrez Gene) FOXO
FOXO3GeneProduct2309 (Entrez Gene) FOXO
FOXO4GeneProduct4303 (Entrez Gene) FOXO
FOXO6GeneProduct100132074 (Entrez Gene) FOXO
FOXP3GeneProduct50943 (Entrez Gene) FoxP3
FYB1GeneProduct2533 (Entrez Gene) ADAP
KCNMA1GeneProduct3778 (Entrez Gene) SLO
KLF6GeneProduct1316 (Entrez Gene) ST12
KNSTRNGeneProduct90417 (Entrez Gene) SKAP)
Kindlin-3GeneProduct
LATS1GeneProduct9113 (Entrez Gene) LATS1)
LATS2GeneProduct
LFA-1GeneProduct
LPLGeneProduct4023 (Entrez Gene) LPL
Lymphocyte motility, migration, thymic egressPathway
MOB1GeneProduct
MST1GeneProduct4485 (Entrez Gene) MST1/2
MST2GeneProduct
NDR1GeneProduct
NDR2GeneProduct
NORE1BGeneProduct
PRDM1GeneProduct639 (Entrez Gene) 尸Blimp1
RAB13GeneProduct5872 (Entrez Gene) Rab13
RAB2AGeneProduct5862 (Entrez Gene) Rab13MST1/2
RAPGeneProduct
RAP1GeneProduct
RAPLGeneProduct
RASSF5GeneProduct83593 (Entrez Gene) RAPL,
RHOAGeneProduct387 (Entrez Gene) RhoA
Rac1GeneProduct
SAV1GeneProduct
SKAPGeneProduct
STK3GeneProduct6788 (Entrez Gene) MST1/2
TAZGeneProduct6901 (Entrez Gene) YAP/TAZ
TEADGeneProduct
TERF2IPGeneProduct54386 (Entrez Gene) RAP1,
YAPGeneProduct
YWHAQGeneProduct10971 (Entrez Gene) 14-3-3
YY1AP1GeneProduct55249 (Entrez Gene) YAP/TAZ
miR-21GeneProduct
p38MAPKGeneProduct

Annotated Interactions

No annotated interactions

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