Leukocyte-intrinsic Hippo pathway functions (Homo sapiens)

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1Myosin IIaLeukocyteIntegrin trafficking and distribution1/2 items only got the one for "1", e.g., MST1/2 and LATS1/2YAP/TAZ only got TAZHard to map from 14-3-3 on fig to YWHAQ hereI think pre-positioning DataNodes would be helpfulAlphabetical?IntracellularVesiclePRDM1APCSMST1Lymphocyte motility, migration,thymic egressSTK3FOXO6RAB2AFOXO4KNSTRNBCRYY1AP1KLF6DR1RHOAFOXO1CXCL10FOXP3RASSF5CD4TERF2IPCCR7TAZFYB1CD8BYAPLPLFOXO3YWHAQKCNMA1CD8ARAB13LATS1PYWHAQPPTAZPPYAPTAZLATS1PLATS2PMOB1PMST1MST2PPSAV1PMOB1PNDR1PNDR2PMST1MST2FOXO6FOXO4PPFOXO1FOXO3PPFOXP3AcFOXP3TEADMST1MST2LPLPLFA-1LFA-1LFA-1LFA-1LFA-1LFA-1MST1MST2RAPRAPLRac1RAPRAPLRac1Kindlin-3Kindlin-3SKAPADAPMST1MST2RAB13Blimp1T.reg PhenotypeLFA-1RAB13RAP1RAPLSKAPRAP1RAPLLFA-1RHOACCR7Lymphocyte polarizationEnhanced BCR humoral responsein B lymphocytesCD19BLIMP1Terminal differentiation/clonalexpansion of CD8+ T cellsMaturation/survival ofT cells in SLORHOAFOXO6FOXO4FOXO1FOXO3Homeostatic maintenanceNORE1BFOXO6FOXO4FOXO1FOXO3miR-21LATS1Cytoarchitecturalintegrity/specificityLFA-1LPLT.h17/T.reg differentiationof CD4+ T cellsFOXO1FOXO3FOXP3p38MAPKAntigen cross presentationby APCsKindlin-3LFA-1Lymphocyte adhesionand extravasationRHOAintegrinsLFA-1


Description

No description

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Quality Tags

Ontology Terms

 

Bibliography

  1. Taha Z, Janse van Rensburg HJ, Yang X; ''The Hippo Pathway: Immunity and Cancer.''; Cancers (Basel), 2018 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
138771view21:36, 2 May 2025Khanspersupdated layout, updated xref for TAZ
120673view01:29, 23 December 2021EweitzModified title
104788view23:55, 14 June 2019AriuttaOntology Term : 'immune response pathway' added !
104787view23:53, 14 June 2019AriuttaOntology Term : 'cancer' added !
104786view23:47, 14 June 2019AriuttaOntology Term : 'T cell' added !
104785view23:45, 14 June 2019AriuttaAdd upregulation interactions
104784view23:03, 14 June 2019AriuttaModified description
104783view22:48, 14 June 2019AriuttaAdd a couple more identifiers.
104780view22:46, 14 June 2019AriuttaAdd edge and more identifiers. Improve layout.
104334view14:05, 17 May 2019FehrhartOntology Term : 'leukocyte' added !
103581view16:16, 18 March 2019Elisson nlGene fixed
103433view09:39, 1 March 2019Marvin M2Ontology Term : 'Hippo signaling pathway' added !
103412view17:03, 27 February 2019AriuttaNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ADAPGeneProduct2533 (Entrez Gene)
APCSGeneProduct325 (Entrez Gene) APCs
BCRGeneProduct613 (Entrez Gene) BCR
BLIMP1GeneProduct
Blimp1GeneProduct639 (Entrez Gene)
CCR7GeneProduct1236 (Entrez Gene) CCR7)
CD19GeneProduct930 (Entrez Gene)
CD4GeneProduct920 (Entrez Gene) CD4+
CD8AGeneProduct925 (Entrez Gene) CD8+
CD8BGeneProduct926 (Entrez Gene) CD8+
CXCL10GeneProduct3627 (Entrez Gene) MOB1
DR1GeneProduct1810 (Entrez Gene) DR1
FOXO1GeneProduct2308 (Entrez Gene) FOXO
FOXO3GeneProduct2309 (Entrez Gene) FOXO
FOXO4GeneProduct4303 (Entrez Gene) FOXO
FOXO6GeneProduct100132074 (Entrez Gene) FOXO
FOXP3GeneProduct50943 (Entrez Gene) FoxP3
FYB1GeneProduct2533 (Entrez Gene) ADAP
KCNMA1GeneProduct3778 (Entrez Gene) SLO
KLF6GeneProduct1316 (Entrez Gene) ST12
KNSTRNGeneProduct90417 (Entrez Gene) SKAP)
Kindlin-3GeneProduct
Kindlin-3GeneProduct83706 (Entrez Gene)
LATS1GeneProduct9113 (Entrez Gene) LATS1)
LATS2GeneProduct26524 (Entrez Gene)
LFA-1GeneProduct
LPLGeneProduct4023 (Entrez Gene) LPL
Lymphocyte motility, migration, thymic egressPathway
MOB1GeneProduct
MOB1GeneProduct55233 (Entrez Gene)
MST1GeneProduct4485 (Entrez Gene) MST1/2
MST2GeneProduct
MST2GeneProduct6788 (Entrez Gene)
NDR1GeneProduct10397 (Entrez Gene)
NDR2GeneProduct23012 (Entrez Gene)
NORE1BGeneProduct
PRDM1GeneProduct639 (Entrez Gene) 尸Blimp1
RAB13GeneProduct5872 (Entrez Gene) Rab13
RAB2AGeneProduct5862 (Entrez Gene) Rab13MST1/2
RAPGeneProduct
RAP1GeneProduct
RAP1GeneProduct54386 (Entrez Gene)
RAPGeneProduct4043 (Entrez Gene)
RAPLGeneProduct
RAPLGeneProduct83593 (Entrez Gene)
RASSF5GeneProduct83593 (Entrez Gene) RAPL,
RHOAGeneProduct387 (Entrez Gene) RhoA
Rac1GeneProduct
Rac1GeneProduct5879 (Entrez Gene)
SAV1GeneProduct60485 (Entrez Gene)
SKAPGeneProduct
SKAPGeneProduct90417 (Entrez Gene)
STK3GeneProduct6788 (Entrez Gene) MST1/2
TAZGeneProduct6901 (Entrez Gene) YAP/TAZ
TEADGeneProduct
TERF2IPGeneProduct54386 (Entrez Gene) RAP1,
YAPGeneProduct
YAPGeneProduct55249 (Entrez Gene)
YWHAQGeneProduct10971 (Entrez Gene) 14-3-3
YY1AP1GeneProduct55249 (Entrez Gene) YAP/TAZ
miR-21GeneProduct406991 (Entrez Gene)
p38MAPKGeneProduct1432 (Entrez Gene)

Annotated Interactions

No annotated interactions

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