Tryptophan metabolism (Bos taurus)

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5-MethoxyindoleacetateL-Tryptophanyl-tRNAOxaloacetate5-Hydroxyindoleacetate5-Hydroxykynurenamine3-Hydroxykynurenamine5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinIndole-3-acetaldoximeKynurenate5-(2'-Formylethyl)-4,6-dihydroxypicolinate2-AminomuconateCinnavalininate7,8-Dihydro-7,8-dihydroxykynurenateC011443-Methoxyanthranilate4,8-Dihydroxyquinoline3-Indoleglycolaldehyde4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate3-Hydroxyanthranilate5-HydroxyindolepyruvateIndole-3-acetate2,3-Dihydroxyindole3-Methylindolepyruvate5-(3'-Carboxy-3'-oxopropyl) -4,6-dihydroxypicolinate2-Amino-3-carboxymuconateFormyl-5-hydroxykynurenamine2-Formaminobenzoylacetate2-OxoglutarateIsophenoxazine3-MethyldioxyindoleQuinolinateN-AcetylindoxylAnthranilate4-(2-Aminophenyl)-2,4-dioxobutanoateIndolepyruvate7,8-DihydroxykynurenateBenzoate degradation via hydroxylationIndole-3-ethanolIndole-3-acetaldehyde(Z)-5-Oxohex-2-enedioateFormyl-N-acetyl-5-methoxykynurenamine2-AminomuconateGlucobrassicinAnthranilate2-Formylaminobenzaldehyde5-Hydroxyindoleacetylglycine6-Hydroxyindolelactate3-Hydroxy-L-kynurenine8-MethoxykynurenateFormylanthranilate2-Oxoadipate3-(2-Aminoethyl)-1H-indol-5-ol6-HydroxykynurenateIndolelactateALDH1A2Acetyl-CoAALDH3A26-Hydroxymelatonin1.14.13.91.13.11.-CYP2F1MAOB2.1.1.493.5.99.5CYP1A11.1.1.110CYP1A21.10.3.4Nicotinate and nicotinamide metabolismRNF25N-Methyltryptamine3.2.1.1472.1.1.47ACAT1DDC2-AminophenolALDH2UBR5CYP19A11.2.1.-1.1.1.190ECHS1Cyp2a13-Indoleacetonitrile4.2.1.84UBE3A1.4.3.2HAAOTDO23.5.1.94.1.99.1ALDH3A2AOX15-(2'-Carboxyethyl)-4,6-Dihydroxypicolinate1.13.12.31.13.11.10GCDH5-Hydroxy-L-tryptophanCyp2d25-Hydroxy-N-formylkynurenine4.1.1.-ASMT4,6-DihydroxyquinolineFormylkynurenine1.1.1.191IDO1KYNUDDCL-TryptophanALDH9A12.6.1.27Indole-3-acetamideGCDHIndoleGlutaryl-CoADDCHRMT1L2HRMT1L24-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoateCYP2E1KYNUBenzoate degradation via hydroxylationUBE3ACYP2C18HADHWARSCYP1B11.2.1.321.3.1.18OGDHCyp2c12Crotonoyl-CoA5-HydroxyindoleacetaldehydeCATPhenylalanine, Tyrosine and Tryptophan metabolismN-AcetylserotoninHRMT1L2CYP2A13TPH14.1.1.43ALDH1A11.14.16.-1.13.11.17Cyp2a2RNF25Aldh1a4ALDH1A1ALDH9A1Cyp2c39MAOBALDH2L-KynurenineINMTN-Acetylisatin3.5.1.49AADATAcetoacetyl-CoA1.14.16.3MDM21.2.3.71.13.11.23ACMSDAADATMDM2CYP7B1N-Methylserotonin1.13.99.3ASMT1.7.3.2IDO13.5.1.45-Hydroxykynurenine2.6.1.27MelatoninMAOBCYP2J2IDO15-MethoxytryptamineAANAT1.14.99.2Glycolysis/GluconeogenesisCYP3A4DHCR24Cyp2b15KYNU2.6.1.27ALDH1A2MAOBABP1HSD17B10CYP4F12Xanthurenic acid3.5.5.1Aldh1a4MDM21.5.1.-TryptamineAFMID


Description

This pathway describes the metabolism of tryptophan, an essential amino acid.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP465(79226) with a 61.0% conversion rate.

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View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
105983view11:51, 16 August 2019MaintBotHMDB identifier normalization
104911view19:20, 24 June 2019KhanspersModified description
104910view19:19, 24 June 2019Khanspersremoved genmapp comments
104820view12:56, 19 June 2019FehrhartModified description
97841view07:56, 10 June 2018EgonwUndo revision 97773 by [[Special:Contributions/Mick Eikelhof|Mick Eikelhof]] ([[User talk:Mick Eikelhof|Talk]])
97773view13:35, 7 June 2018Mick EikelhofModified description
85056view10:50, 10 April 2016Egonw
80880view15:29, 30 June 2015MkutmonNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
(Z)-5-Oxohex-2-enedioateMetabolite(Z)-5-Oxohex-2-enedioate
1.1.1.110GeneProduct
1.1.1.190GeneProduct
1.1.1.191GeneProduct
1.10.3.4GeneProduct
1.13.11.-GeneProduct
1.13.11.10GeneProduct
1.13.11.17GeneProduct
1.13.11.23GeneProduct
1.13.12.3GeneProduct
1.13.99.3GeneProduct
1.14.13.9GeneProduct
1.14.16.-GeneProduct
1.14.16.3GeneProduct
1.14.99.2GeneProduct
1.2.1.-GeneProduct
1.2.1.32GeneProduct
1.2.3.7GeneProduct
1.3.1.18GeneProduct
1.4.3.2GeneProduct
1.5.1.-GeneProduct
1.7.3.2GeneProduct
2,3-DihydroxyindoleMetabolite20546 (Chemspider)
2-Amino-3-carboxymuconateMetabolite2-Amino-3-carboxymuconate
2-AminomuconateMetabolite2-Aminomuconate
2-AminophenolMetabolite95-55-6 (CAS) 2-Aminophenol
2-Formamino benzoylacetateMetabolite2-Formaminobenzoylacetate
2-FormylaminobenzaldehydeMetabolite389 (Chemspider)
2-OxoadipateMetabolite19951093 (Chemspider) 2-Oxoadipate
2-OxoglutarateMetabolite144236 (Chemspider) 2-Oxoglutarate
2.1.1.47GeneProduct
2.1.1.49GeneProduct
2.6.1.27GeneProduct
3-(2-Aminoethyl) -1H-indol-5-olMetabolite5013 (Chemspider) 3-(2-Aminoethyl)-1H-indol-5-ol
3-Hydroxy- L-kynurenineMetabolite3-Hydroxy-L-kynurenine
3-HydroxyanthranilateMetabolite7822291 (Chemspider) 3-Hydroxyanthranilate
3-HydroxykynurenamineMetabolite3-Hydroxykynurenamine
3-IndoleacetonitrileMetabolite771-51-7 (CAS) 3-Indoleacetonitrile
3-IndoleglycolaldehydeMetabolite388979 (Chemspider)
3-MethoxyanthranilateMetabolite7827589 (Chemspider) 3-Methoxyanthranilate
3-MethyldioxyindoleMetabolite
3-MethylindolepyruvateMetabolite3-Methylindolepyruvate
3.2.1.147GeneProduct
3.5.1.4GeneProduct
3.5.1.49GeneProduct
3.5.1.9GeneProduct
3.5.5.1GeneProduct
3.5.99.5GeneProduct
4,6-DihydroxyquinolineMetaboliteHMDB04077 (HMDB)
4,8-DihydroxyquinolineMetabolite389608 (Chemspider) 4,8-Dihydroxyquinoline
4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoateMetaboliteHMDB04083 (HMDB)
4-(2-Amino-5-hydroxyphenyl) -2,4-dioxobutanoateMetabolite389617 (Chemspider) 4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate
4-(2-Aminophenyl)-2,4-dioxobutanoateMetabolite19951260 (Chemspider) 4-(2-Aminophenyl)-2,4-dioxobutanoate
4.1.1.-GeneProduct
4.1.1.43GeneProduct
4.1.99.1GeneProduct
4.2.1.84GeneProduct
5-(2'-Carboxyethyl)-4,6-DihydroxypicolinateMetaboliteHMDB06794 (HMDB)
5-(2'-Formylethyl)-4,6-dihydroxypicolinateMetabolite30791294 (Chemspider) 5-(2'-Formylethyl)-4,6-dihydroxypicolinate
5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinMetabolite5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinate
5-(3'-Carboxy-3'-oxopropyl) -4,6-dihydroxypicolinateMetabolite30791292 (Chemspider) 5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate
5-Hydroxy-L-tryptophanMetaboliteHMDB00472 (HMDB)
5-Hydroxy-N-formylkynurenineMetaboliteHMDB04086 (HMDB)
5-HydroxyindoleacetaldehydeMetaboliteHMDB04073 (HMDB)
5-HydroxyindoleacetateMetabolite10637170 (Chemspider) 5-Hydroxyindoleacetate
5-HydroxyindoleacetylglycineMetabolite
5-HydroxyindolepyruvateMetabolite
5-HydroxykynurenamineMetabolite5-Hydroxykynurenamine
5-HydroxykynurenineMetabolite484-78-6 (CAS)
5-MethoxyindoleacetateMetabolite14533147 (Chemspider) 5-Methoxyindoleacetate
5-MethoxytryptamineMetabolite608-07-1 (CAS)
6-HydroxyindolelactateMetabolite6-Hydroxyindolelactate
6-HydroxykynurenateMetabolite6-Hydroxykynurenate
6-HydroxymelatoninMetabolite2208-41-5 (CAS)
7,8-Dihydro-7,8-dihydroxykynurenateMetabolite7,8-Dihydro-7,8-dihydroxykynurenate
7,8-DihydroxykynurenateMetabolite7,8-Dihydroxykynurenate
8-MethoxykynurenateMetabolite8-Methoxykynurenate
AADATGeneProductENSBTAG00000010326 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:51166
AANATGeneProductENSBTAG00000014682 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:15
ABP1GeneProductENSBTAG00000005419 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:26
ACAT1GeneProductENSBTAG00000012885 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:38
ACMSDGeneProductENSBTAG00000008039 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:130013
AFMIDGeneProductENSBTAG00000007125 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:125061
ALDH1A1GeneProductENSBTAG00000008103 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:216
ALDH1A2GeneProductENSBTAG00000010119 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8854
ALDH2GeneProductENSBTAG00000008743 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:217
ALDH3A2GeneProductENSBTAG00000039161 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:224
ALDH9A1GeneProductENSBTAG00000017852 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:223
AOX1GeneProductENSBTAG00000009725 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:316
ASMTGeneProductENSBTAG00000047124 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:438
Acetoacetyl-CoAMetaboliteC00332 (KEGG Compound)
Acetyl-CoAMetabolite72-89-9 (CAS) Acetyl-CoA
Aldh1a4GeneProduct
AnthranilateMetabolite4573598 (Chemspider) Anthranilate
Benzoate degradation via hydroxylationPathway
C01144Metabolite(S)-3-Hydroxybutanoyl-CoA
CATGeneProductENSBTAG00000020980 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:847
CYP19A1GeneProductENSBTAG00000014890 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1588
CYP1A1GeneProductENSBTAG00000001021 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1543
CYP1A2GeneProductENSBTAG00000000085 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1544
CYP1B1GeneProductENSBTAG00000010531 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1545
CYP2A13GeneProductENSBTAG00000047815 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1553
CYP2C18GeneProductENSBTAG00000020375 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1562
CYP2E1GeneProductENSBTAG00000018365 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1571
CYP2F1GeneProductENSBTAG00000046805 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1572
CYP2J2GeneProductENSBTAG00000013693 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1573
CYP3A4GeneProductENSBTAG00000047379 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1576
CYP4F12GeneProductENSBTAG00000038549 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:66002
CYP7B1GeneProductENSBTAG00000001299 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9420
CinnavalininateMetaboliteCinnavalininate
Crotonoyl-CoAMetaboliteC00877 (KEGG Compound)
Cyp2a1GeneProduct
Cyp2a2GeneProduct
Cyp2b15GeneProduct
Cyp2c12GeneProduct
Cyp2c39GeneProduct
Cyp2d2GeneProduct
DDCGeneProductENSBTAG00000020869 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1644
DHCR24GeneProductENSBTAG00000004688 (Ensembl)
  • predicted
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1718
ECHS1GeneProductENSBTAG00000017710 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1892
Formyl-5-hydroxykynurenamineMetabolite
Formyl-N-acetyl-5- methoxykynurenamineMetaboliteFormyl-N-acetyl-5-methoxykynurenamine
FormylanthranilateMetaboliteFormylanthranilate
FormylkynurenineMetabolite1022-31-7 (CAS) Formylkynurenine
GCDHGeneProductENSBTAG00000016211 (Ensembl)
  • predicted
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2639
GlucobrassicinMetaboliteGlucobrassicin
Glutaryl-CoAMetaboliteC00527 (KEGG Compound)
Glycolysis/GluconeogenesisPathwayWP534 (WikiPathways)
HAAOGeneProductENSBTAG00000004674 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:23498
HADHGeneProductENSBTAG00000002049 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3033
HRMT1L2GeneProductENSBTAG00000001357 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3276
HSD17B10GeneProductENSBTAG00000017779 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3028
IDO1GeneProductENSBTAG00000020602 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3620
INMTGeneProductENSBTAG00000001448 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:11185
Indole-3-acetaldehydeMetabolite778 (Chemspider) Indole-3-acetaldehyde
Indole-3-acetaldoximeMetabolite388896 (Chemspider) Indole-3-acetaldoxime
Indole-3-acetamideMetabolite879-37-8 (CAS) Indole-3-acetamide
Indole-3-acetateMetabolite779 (Chemspider) Indole-3-acetate
Indole-3-ethanolMetabolite10235 (Chemspider)
IndoleMetabolite120-72-9 (CAS)
IndolelactateMetabolite28571995 (Chemspider) Indolelactate
IndolepyruvateMetabolite24775813 (Chemspider) Indolepyruvate
IsophenoxazineMetaboliteIsophenoxazine
KYNUGeneProductENSBTAG00000032277 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8942
KynurenateMetabolite4-Hydroxy-2-quinolinecarboxylic
L-KynurenineMetabolite343-65-7 (CAS) L-Kynurenine
L-TryptophanMetabolite73-22-3 (CAS)
L-Tryptophanyl-tRNAMetabolite
MAOBGeneProductENSBTAG00000001288 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4129
MDM2GeneProductENSBTAG00000010422 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4193
MelatoninMetaboliteHMDB01389 (HMDB)
N-AcetylindoxylMetaboliteN-Acetylindoxyl
N-AcetylisatinMetabolite574-17-4 (CAS) N-Acetylisatin
N-AcetylserotoninMetabolite1210-83-9 (CAS) N-Acetylserotonin
N-MethylserotoninMetaboliteHMDB04369 (HMDB)
N-MethyltryptamineMetaboliteCHEBI:28136 (ChEBI)
Nicotinate and nicotinamide metabolismPathway
OGDHGeneProductENSBTAG00000006029 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4967
OxaloacetateMetabolite2509917 (Chemspider) Oxaloacetate
Phenylalanine, Tyrosine and Tryptophan metabolismPathway
QuinolinateMetabolite2777129 (Chemspider)
RNF25GeneProductENSBTAG00000003817 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:64320
TDO2GeneProductENSBTAG00000011062 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6999
TPH1GeneProductENSBTAG00000005343 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7166
TryptamineMetabolite61-54-1 (CAS)
UBE3AGeneProductENSBTAG00000002487 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7337
UBR5GeneProductENSBTAG00000021209 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:51366
WARSGeneProductENSBTAG00000004679 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7453
Xanthurenic acidMetaboliteHMDB00881 (HMDB)

Annotated Interactions

No annotated interactions
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