TCA cycle (Anopheles gambiae)

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Degradation of Fatty AcidsContaining an Odd Number of CarbonsElectron Transport ChainGluconeogenesisMitochondrionFatty Acid SynthesisDegradation of Fatty AcidsContaining an Even Number of CarbonsCytosolGlycolysisAgaP_AGAP011629AgaP_AGAP001312PDK1AgaP_AGAP007852Succinyl-CoAPyruvateAgaP_AGAP004055PDK4AgaP_AGAP002192FumarateOxaloacetateAgaP_AGAP008349AgaP_AGAP010672AgaP_AGAP001903IsocitrateAgaP_AGAP011629PDK2AgaP_AGAP003030OxaloacetateAgaP_AGAP010276SuccinateAgaP_AGAP001884Acetyl-CoAAgaP_AGAP006366AgaP_AGAP010429AgaP_AGAP004744AgaP_AGAP004352PDHXAgaP_AGAP012048PDP2AgaP_AGAP007786PDHA2MalateMalatealpha-KetoglutarateAgaP_AGAP009510AgaP_AGAP004742AgaP_AGAP003168AgaP_AGAP007309AgaP_AGAP007975AgaP_AGAP002728CitrateAgaP_AGAP010421AgaP_AGAP000618


Description

The citric acid cycle, also known as the tricarboxylic acid cycle (TCA cycle) or the Krebs cycle, (or rarely, the Szent-Gyorgyi-Krebs cycle) is a series of enzyme-catalysed chemical reactions of central importance in all living cells that use oxygen as part of cellular respiration. In eukaryotes, the citric acid cycle occurs in the matrix of the mitochondrion. The components and reactions of the citric acid cycle were established by seminal work from both Albert Szent-Gyorgyi and Hans Krebs. [From Wikipedia]

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP78(r28870) with a 81% conversion rate.

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Bibliography

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History

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CompareRevisionActionTimeUserComment
117225view09:30, 19 May 2021EweitzModified title
105889view08:57, 16 August 2019MkutmonHMDB identifier unification
87713view09:13, 25 July 2016MirellaKalafatiOntology Term : 'citric acid cycle pathway' added !
87712view09:13, 25 July 2016MirellaKalafatiOntology Term : 'classic metabolic pathway' added !
68436view19:10, 5 July 2013MaintBotUpdated to 2013 gpml schema
40467view18:47, 1 March 2011MaintBotRemoved redundant pathway information and comments
32284view13:09, 15 August 2009MaintBotFixed text labels
31834view12:27, 14 August 2009MaintBotFixed group labels
31312view20:14, 13 August 2009MaintBotFixed text labels
30796view23:42, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
Acetyl-CoAMetaboliteHMDB0001206 (HMDB)
AgaP_AGAP000618GeneProduct1271698 (Entrez Gene)
AgaP_AGAP001312GeneProduct1281865 (Entrez Gene)
AgaP_AGAP001884GeneProduct1281238 (Entrez Gene)
AgaP_AGAP001903GeneProduct1281223 (Entrez Gene)
AgaP_AGAP002192GeneProduct1269365 (Entrez Gene)
AgaP_AGAP002728GeneProduct1273240 (Entrez Gene)
AgaP_AGAP003030GeneProduct1272922 (Entrez Gene)
AgaP_AGAP003168GeneProduct1273838 (Entrez Gene)
AgaP_AGAP004055GeneProduct1270895 (Entrez Gene)
AgaP_AGAP004352GeneProduct1274499 (Entrez Gene)
AgaP_AGAP004742GeneProduct1278483 (Entrez Gene)
AgaP_AGAP004744GeneProduct1278481 (Entrez Gene)
AgaP_AGAP006366GeneProduct1276976 (Entrez Gene)
AgaP_AGAP007309GeneProduct1269860 (Entrez Gene)
AgaP_AGAP007786GeneProduct1278179 (Entrez Gene)
AgaP_AGAP007852GeneProduct1278105 (Entrez Gene)
AgaP_AGAP007975GeneProduct1277974 (Entrez Gene)
AgaP_AGAP008349GeneProduct1277632 (Entrez Gene)
AgaP_AGAP009510GeneProduct1271401 (Entrez Gene)
AgaP_AGAP010276GeneProduct1279699 (Entrez Gene)
AgaP_AGAP010421GeneProduct1272627 (Entrez Gene)
AgaP_AGAP010429GeneProduct1272618 (Entrez Gene)
AgaP_AGAP010672GeneProduct1272475 (Entrez Gene)
AgaP_AGAP011629GeneProduct1281003 (Entrez Gene)
AgaP_AGAP012048GeneProduct1280620 (Entrez Gene)
CitrateMetaboliteHMDB0000094 (HMDB)
FumarateMetaboliteHMDB0000134 (HMDB)
IsocitrateMetaboliteHMDB0000193 (HMDB)
MalateMetaboliteHMDB0000156 (HMDB)
OxaloacetateMetaboliteHMDB0000223 (HMDB)
PDHA2GeneProduct
PDHXGeneProduct
PDK1GeneProduct
PDK2GeneProduct
PDK4GeneProduct
PDP2GeneProduct
PyruvateMetaboliteHMDB0000243 (HMDB)
SuccinateMetaboliteHMDB0000254 (HMDB)
Succinyl-CoAMetaboliteHMDB0001022 (HMDB)
alpha-KetoglutarateMetabolite

Annotated Interactions

No annotated interactions
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