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2-Oxoadipate 2-Formamino benzoylacetate 4-(2-Amino-5-hydroxyphenyl) -2,4-dioxobutanoate 2,3-Dihydroxyindole 3-Methylindolepyruvate 5-Hydroxykynurenamine Indolepyruvate (Z)-5-Oxohex-2-enedioate Kynurenate Oxaloacetate Indole-3-acetaldoxime 2-Formylaminobenzaldehyde Glucobrassicin 2-Aminomuconate Formyl-N-acetyl-5- methoxykynurenamine Anthranilate 5-Methoxyindoleacetate 2-Aminomuconate 6-Hydroxyindolelactate 3-Methyldioxyindole 2-Oxoglutarate Indole-3-acetate 5-Hydroxyindolepyruvate 3-(2-Aminoethyl) -1H-indol-5-ol Indole-3-ethanol Quinolinate Benzoate degradation via hydroxylation 4,8-Dihydroxyquinoline 5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolin 5-(3'-Carboxy-3'-oxopropyl) -4,6-dihydroxypicolinate Isophenoxazine 7,8-Dihydro-7,8-dihydroxykynurenate 8-Methoxykynurenate Formylanthranilate 3-Hydroxykynurenamine Indole-3-acetaldehyde 4-(2-Aminophenyl)-2,4-dioxobutanoate 5-Hydroxyindoleacetate N-Acetylindoxyl 5-Hydroxyindoleacetylglycine Cinnavalininate 3-Hydroxyanthranilate 5-(2'-Formylethyl)-4,6-dihydroxypicolinate 2-Amino-3-carboxymuconate 3-Hydroxy- L-kynurenine 7,8-Dihydroxykynurenate 3-Methoxyanthranilate Anthranilate 3-Indoleglycolaldehyde 6-Hydroxykynurenate C01144 L-Tryptophanyl-tRNA Indolelactate Formyl-5-hydroxykynurenamine CYP19A1 1.4.3.2 KYNU 1.14.16.3 ALDH9A1 1.13.11.23 CYP2A13 ALDH2 5-Hydroxykynurenine ACMSD Xanthurenic acid ALDH1A2 N-Methylserotonin 2.1.1.47 3.5.1.9 HAAO Aldh1a4 AOX1 IDO1 CYP1A1 CYP7B1 2-Aminophenol N-Methyltryptamine CYP1B1 CYP2C18 AFMID DHCR24 OGDH 1.14.13.9 TDO2 AANAT 3.5.1.4 UBR5 DDC 5-Methoxytryptamine 1.14.16.- 5-Hydroxy-L-tryptophan ACAT1 1.14.99.2 1.13.99.3 MDM2 MAOB HRMT1L2 GCDH KYNU TPH1 Phenylalanine, Tyrosine and Tryptophan metabolism 3-Indoleacetonitrile CYP2F1 RNF25 3.2.1.147 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate HSD17B10 2.6.1.27 Cyp2a1 1.1.1.190 4.1.1.- KYNU 1.7.3.2 MAOB ALDH1A1 ALDH1A2 RNF25 Melatonin 1.2.1.- CYP1A2 UBE3A Cyp2a2 Crotonoyl-CoA Cyp2b15 INMT Glycolysis/Gluconeogenesis 5-Hydroxy-N-formylkynurenine ALDH3A2 1.1.1.110 MAOB 3.5.99.5 1.13.12.3 6-Hydroxymelatonin CYP3A4 1.1.1.191 MDM2 2.6.1.27 IDO1 1.13.11.- AADAT L-Tryptophan ASMT 1.13.11.10 Tryptamine 5-(2'-Carboxyethyl)-4,6-Dihydroxypicolinate Indole-3-acetamide 3.5.1.49 3.5.5.1 N-Acetylisatin UBE3A HRMT1L2 5-Hydroxyindoleacetaldehyde AADAT ABP1 Acetyl-CoA ALDH3A2 N-Acetylserotonin 1.5.1.- CYP2J2 1.10.3.4 Indole MAOB Nicotinate and nicotinamide metabolism HRMT1L2 4.1.1.43 Glutaryl-CoA HADH CYP2E1 Cyp2d2 ALDH9A1 1.2.1.32 1.3.1.18 CYP4F12 Cyp2c39 1.13.11.17 IDO1 4.2.1.84 2.1.1.49 GCDH 1.2.3.7 ASMT 4,6-Dihydroxyquinoline ALDH2 WARS CAT Formylkynurenine ALDH1A1 DDC 4.1.99.1 MDM2 Aldh1a4 2.6.1.27 Benzoate degradation via hydroxylation Acetoacetyl-CoA Cyp2c12 DDC ECHS1 L-Kynurenine
Description
This pathway describes the metabolism of tryptophan, an essential amino acid.
Originally converted from rat to human using ortholog information. Edited by Sebastien Burel
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