Transcriptional activation by Nfe2l2 in response to phytochemicals (Mus musculus)
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1
Phase II enzymes
ARE
T-P
Nucleus
CCAAT/XRE
S-P
S-P
T-P
Nfe2l2
Hmox1
Keap1
Cebpb
Mapk8
Sulforaphane
Keap1
Gsta2
Curcumin
Cebpb
6-HITC
Gclc
Nfe2l2
Prkca
Nqo1
Gclm
Maf
Pik3ca
Aimp2
Ephb2
Caffeic acid phenethyl ester
Nfe2l2
Description
Based on
Surh, 2003, figure 4
.
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP3(r29720)
with a 94% conversion rate.
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Quality Tags
Ontology Terms
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Bibliography
Surh YJ; ''Cancer chemoprevention with dietary phytochemicals.''; Nat Rev Cancer, 2003
PubMed
Europe PMC
Scholia
History
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Action
Time
User
Comment
116708
view
09:37, 11 May 2021
Eweitz
Modified title
106837
view
13:31, 17 September 2019
MaintBot
HMDB identifier normalization
89978
view
18:45, 6 October 2016
Mkutmon
fix unconnected lines
71125
view
11:44, 7 October 2013
Susan
Connected lines
69176
view
18:21, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67419
view
10:59, 26 June 2013
Ddigles
Ontology Term : 'nuclear factor, erythroid derived 2, like 2 signaling pathway' added !
48229
view
05:32, 17 May 2012
MaintBot
Automatic update of PubChem xrefs
41366
view
00:28, 2 March 2011
MaintBot
Removed redundant pathway information and comments
32699
view
18:17, 1 September 2009
MaintBot
added xref
31850
view
12:32, 14 August 2009
MaintBot
Fixed group labels
30829
view
00:01, 30 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
6-HITC
Metabolite
Full name: 6-(Methylsulfinyl)hexylisothiocyanate, or Japanese horseradish wasabi
Aimp2
GeneProduct
231872 (Entrez Gene)
Caffeic acid phenethyl ester
Metabolite
Cebpb
GeneProduct
12608 (Entrez Gene)
Curcumin
Metabolite
HMDB0002269 (HMDB)
Ephb2
GeneProduct
13844 (Entrez Gene)
Gclc
GeneProduct
14629 (Entrez Gene)
Gclm
GeneProduct
14630 (Entrez Gene)
Gsta2
GeneProduct
14858 (Entrez Gene)
Hmox1
GeneProduct
15368 (Entrez Gene)
Keap1
GeneProduct
50868 (Entrez Gene)
Maf
GeneProduct
17132 (Entrez Gene)
Mapk8
GeneProduct
26419 (Entrez Gene)
Nfe2l2
GeneProduct
18024 (Entrez Gene)
Nqo1
GeneProduct
18104 (Entrez Gene)
Pik3ca
GeneProduct
18706 (Entrez Gene)
Prkca
GeneProduct
18750 (Entrez Gene)
Sulforaphane
Metabolite
HMDB0005792 (HMDB)
Annotated Interactions
No annotated interactions
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View approved pathways at the new wikipathways.org.Quality Tags
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No annotated interactions