HIPK2 in kidney fibrosis (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Jin Y, Ratnam K, Chuang PY, Fan Y, Zhong Y, Dai Y, Mazloom AR, Chen EY, D'Agati V, Xiong H, Ross MJ, Chen N, Ma'ayan A, He JC; ''A systems approach identifies HIPK2 as a key regulator of kidney fibrosis.''; Nat Med, 2012 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	141967	view	16:24, 28 November 2025	Eweitz	Clear cached dimensions
	141966	view	16:24, 28 November 2025	Eweitz	Economize layout
	137915	view	17:37, 10 March 2025	Khanspers	Modified description
	123418	view	06:12, 26 July 2022	Egonw	Made five pathways clickable
	120779	view	22:23, 4 January 2022	Khanspers	updated layout and pathway labels
	120775	view	21:27, 4 January 2022	Khanspers	Modified description
	120774	view	20:16, 4 January 2022	Khanspers	Modified description
	108288	view	16:55, 4 December 2019	AgustinGV
	108287	view	16:54, 4 December 2019	AgustinGV
	108286	view	16:52, 4 December 2019	AgustinGV
	108025	view	21:15, 22 November 2019	AgustinGV
	108024	view	21:13, 22 November 2019	AgustinGV
	108023	view	21:10, 22 November 2019	AgustinGV
	108022	view	20:59, 22 November 2019	AgustinGV	Ontology Term : 'renal fibrosis' added !
	108021	view	20:58, 22 November 2019	AgustinGV	Ontology Term : 'kidney disease pathway' added !
	108019	view	20:55, 22 November 2019	AgustinGV	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
Apoptosis
ETM markers
HIPK2	GeneProduct	28996 (Entrez Gene)
Inflammation
KIDNEY FIBROSIS
NF-kB	Pathway	WP4562 (WikiPathways)
Notch	Pathway	WP268 (WikiPathways)
ROS DNA damage
SIAH1	GeneProduct	6477 (Entrez Gene)
TGF-B	Pathway	WP3874 (WikiPathways)
Wnt_B-catenin	Pathway	WP4150 (WikiPathways)
p53	Pathway	WP707 (WikiPathways)

Annotated Interactions

No annotated interactions