Base excision repair (Homo sapiens)

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Revision as of 22:25, 23 November 2019 by Khanspers (Talk | contribs)
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AP siteShort patch BERGap fillingRecognition by glycosylasesand removal of damaged baseOxidized or ring-saturated base5'OHOGG1PARP1APEX1PNKPNTHL1NTHL1NEIL2NEIL3APEX25'3'3'3' hydroxyl adjacent to5' deoxyribosephosphate (dRP)XRCC1LIG3LIG1End processingPOLBXRCC1Ligation5'5'3'3'5'5'3'3'5'5'3'3'5'5'3'3'Long patch BER5'5'3'3'Deaminated, alkylatedor mismatched baseUNGSMUG1MUTYHMPGMBD4TDG5'5'3'3'APEX1APEX2OH5'5'3'3'POLBPOLLHMGB1POLBPOLEPOLD1POLD2POLE2POLE3POLE4POLD3POLD4PCNA5'5'3'3'PCNAFEN15'5'3'3'5'5'3'3'PCNALigationGap filling andstrand displacementAP sitePARP2PARP1PARP2


Description

Base Excision Repair - draft

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Quality Tags

Ontology Terms

 

Bibliography

  1. ''REPAIRtoire''; http://repairtoire.genesilico.pl/Pathway/4/,
  2. ''KEGG''; https://www.genome.jp/dbget-bin/www_bget?map03410,

History

View all...
CompareRevisionActionTimeUserComment
127650view23:16, 13 November 2023Khanspersadded id and db for repairtoire lit ref
125305view17:47, 31 January 2023LarsgwFix reference
119239view19:09, 22 June 2021Finterlyadded KEGG biopax information
117660view11:52, 22 May 2021EweitzModified title
110588view21:08, 19 May 2020Khanspersminor update
108597view23:49, 9 January 2020KhanspersModified description
108050view00:41, 27 November 2019Khanspersadded references
108049view00:39, 27 November 2019KhanspersModified description
108032view22:37, 23 November 2019KhanspersOntology Term : 'DNA repair pathway' added !
108031view22:37, 23 November 2019KhanspersOntology Term : 'base excision repair pathway' added !
108030view22:36, 23 November 2019KhanspersModified description
108029view22:26, 23 November 2019Khanspersfixed interaction
108028view22:25, 23 November 2019Khanspersupdated complexes
108027view22:24, 23 November 2019KhanspersAdded PARPs
108026view01:16, 23 November 2019KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
APEX1GeneProductENSG00000100823 (Ensembl)
APEX2GeneProductENSG00000169188 (Ensembl)
FEN1GeneProductENSG00000168496 (Ensembl)
HMGB1GeneProductENSG00000189403 (Ensembl)
LIG1GeneProductENSG00000105486 (Ensembl)
LIG3GeneProductENSG00000005156 (Ensembl)
MBD4GeneProductENSG00000129071 (Ensembl)
MPGGeneProductENSG00000103152 (Ensembl)
MUTYHGeneProductENSG00000132781 (Ensembl)
NEIL2GeneProductENSG00000154328 (Ensembl)
NEIL3GeneProductENSG00000109674 (Ensembl)
NTHL1GeneProductENSG00000065057 (Ensembl)
OGG1GeneProductENSG00000114026 (Ensembl)
PARP1GeneProductENSG00000143799 (Ensembl)
PARP2GeneProductENSG00000129484 (Ensembl)
PCNAGeneProductENSG00000132646 (Ensembl)
PNKPGeneProductENSG00000039650 (Ensembl) PKNP has a kinase domain which phosphorylates 5' hydroxyl ends, and a phosphatase domain, which removes phosphates from 3' ends.
POLBGeneProductENSG00000070501 (Ensembl)
POLD1GeneProductENSG00000062822 (Ensembl)
POLD2GeneProductENSG00000106628 (Ensembl)
POLD3GeneProductENSG00000077514 (Ensembl)
POLD4GeneProductENSG00000175482 (Ensembl)
POLE2GeneProductENSG00000100479 (Ensembl)
POLE3GeneProductENSG00000148229 (Ensembl)
POLE4GeneProductENSG00000115350 (Ensembl)
POLEGeneProductENSG00000177084 (Ensembl)
POLLGeneProductENSG00000166169 (Ensembl)
SMUG1GeneProductENSG00000123415 (Ensembl)
TDGGeneProductENSG00000139372 (Ensembl)
UNGGeneProductENSG00000076248 (Ensembl)
XRCC1GeneProductENSG00000073050 (Ensembl)

Annotated Interactions

No annotated interactions

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