Conversion of angiotensinogen to angiotensin II (Homo sapiens)
From WikiPathways
Description
This pathway depicts the conversion of Angiotensinogen to Angiotensin II by enzymes of the Renin-Angiotensin-System (RAS) and Nonrenin-Angiotensin-System (NRAS).
The NRAS pathway includes both direct and indirect conversion.
Quality Tags
Ontology Terms
Bibliography
- Karlsson C, Lindell K, Ottosson M, Sjöström L, Carlsson B, Carlsson LM; ''Human adipose tissue expresses angiotensinogen and enzymes required for its conversion to angiotensin II.''; J Clin Endocrinol Metab, 1998 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
ACE | GeneProduct | ENSG00000159640 (Ensembl) | |
Angiotensin I | Metabolite | CHEBI:2718 (ChEBI) | |
Angiotensinogen | Metabolite | CHEBI:2720 (ChEBI) | |
Cathepsin D | Protein | A0A1B0GV23 (Uniprot-TrEMBL) | |
Cathepsin G | Protein | P08311 (Uniprot-TrEMBL) | |
Chymase | Protein | P23946 (Uniprot-TrEMBL) | |
Renin | Protein | A0A1B0GUZ2 (Uniprot-TrEMBL) | |
human angiotensin II | Metabolite | CHEBI:2719 (ChEBI) |
Annotated Interactions
No annotated interactions