Cytokines and inflammatory response (Pan troglodytes)
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1
Clonal expansion of T cells
Lymphocyte Activated
Killer Cells (LAK)
Eos
Hypothalamus
(fever)
Fibroblasts
Eos
B Cell
NK cell
Th
Tc
Tc
antigen
Th
B Cell
Hematopoietic Stem Cell
antibodies
Eos
B Cell
Mast Cell
T-helper
B Cell
T-helper
Th
Macrophage
Plasma Cell
Tc
Endothelial Cells
Hematopoiesis
TCR
Neutrophil
MHC II
CSF2
TNF
IL3
TRA
IL6
IL1A
IL1A
IL2
IL12B
LOC473183
IL7
CSF3
IL1B
IL10
TGFB1
Inflammatory Response
IL10
IL2
CXCL1
CSF2
IL3
IL13
PATR-DRA
TNF
TNF
IL2
IL6
IL1A
TNF
IL15
CD4
IL1B
IL4
PDGFA
IL6
IL10
IL5
IL15
IL13
IL3
IFNG
IL12B
IL2
IFN1@
IL5
IL1A
IL15
IL4
IL4
TGFB1
IL1B
TNF
IL11
IL1B
IL10
IFNG
IL2
HLA-DRB1
IL6
IL4
IL2
IL2
CXCL2
IL6
IFNG
TNF
IL12
IL1B
TNF
TRB
IL4
CSF1
TGFB1
IL1A
IFN1@
IL3
Description
See BioCarta version:
http://www.biocarta.com/pathfiles/h_inflamPathway.asp
Comments
GenMAPP remarks
Converted to human by GenMAPP.org
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP530(r21794)
with a 80% conversion rate.
Try the New WikiPathways
View approved pathways at
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Quality Tags
Ontology Terms
Saving...
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Bibliography
Kataoka T; ''Chemical biology of inflammatory cytokine signaling.''; J Antibiot (Tokyo), 2009
PubMed
Europe PMC
Scholia
History
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Compare
Revision
Action
Time
User
Comment
117385
view
10:32, 21 May 2021
Eweitz
Modified title
111168
view
13:35, 21 July 2020
Egonw
Made another pathway clickable
111046
view
12:27, 3 July 2020
L Dupuis
Connected lines
86905
view
08:00, 14 July 2016
Mkutmon
Ontology Term : 'inflammatory response pathway' added !
86904
view
08:00, 14 July 2016
Mkutmon
Ontology Term : 'PW:0000028' removed !
71866
view
21:23, 18 October 2013
MaintBot
Modified title
69273
view
18:39, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67131
view
10:10, 26 June 2013
Christine Chichester
Ontology Term : 'inflammatory response pathway' added !
41582
view
02:00, 2 March 2011
MaintBot
Removed redundant pathway information and comments
38655
view
12:55, 23 September 2010
FerryJagers
fixed database @ linked pathway
38652
view
12:44, 23 September 2010
FerryJagers
Linked pathway
35250
view
19:57, 11 February 2010
Thomas
added literature
34310
view
22:08, 9 December 2009
MaintBot
Automatic update of empty xrefs
33543
view
09:38, 1 December 2009
MaintBot
Removed group label
31573
view
21:59, 13 August 2009
MaintBot
Fixed text labels
30448
view
21:25, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
Inflammatory Response
Pathway
WP920 (WikiPathways)
CD4
GeneProduct
450124 (Entrez Gene)
CSF1
GeneProduct
457127 (Entrez Gene)
CSF2
GeneProduct
471627 (Entrez Gene)
CSF3
GeneProduct
CXCL1
GeneProduct
740567 (Entrez Gene)
CXCL2
GeneProduct
740176 (Entrez Gene)
HLA-DRB1
GeneProduct
IFN1@
GeneProduct
IFNG
GeneProduct
449517 (Entrez Gene)
IL10
GeneProduct
469657 (Entrez Gene)
IL11
GeneProduct
736204 (Entrez Gene)
IL12
GeneProduct
IL12B
GeneProduct
471723 (Entrez Gene)
IL13
GeneProduct
449564 (Entrez Gene)
IL15
GeneProduct
737808 (Entrez Gene)
IL1A
GeneProduct
470485 (Entrez Gene)
IL1B
GeneProduct
450200 (Entrez Gene)
IL2
GeneProduct
461472 (Entrez Gene)
IL3
GeneProduct
471626 (Entrez Gene)
IL4
GeneProduct
449565 (Entrez Gene)
IL5
GeneProduct
743963 (Entrez Gene)
IL6
GeneProduct
463288 (Entrez Gene)
IL7
GeneProduct
464245 (Entrez Gene)
LOC473183
GeneProduct
473183 (Entrez Gene)
PATR-DRA
GeneProduct
462591 (Entrez Gene)
PDGFA
GeneProduct
TGFB1
GeneProduct
456060 (Entrez Gene)
TNF
GeneProduct
744399 (Entrez Gene)
TRA
GeneProduct
TRB
GeneProduct
Annotated Interactions
No annotated interactions
Views
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Discussion
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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DataNodes
Annotated Interactions
No annotated interactions