p53 transcriptional gene network (Homo sapiens)
From WikiPathways
Description
p53 Transcriptional Gene Network
Quality Tags
Ontology Terms
Bibliography
- Levine AJ; ''p53: 800million years of evolutionand 40 years of discovery.''; Nat Rev Cancer, 2020 PubMed Europe PMC Scholia
- Kaiser AM, Attardi LD; ''Deconstructing networks of p53-mediated tumor suppression in vivo.''; Cell Death Differ, 2018 PubMed Europe PMC Scholia
- Hernández Borrero LJ, El-Deiry WS; ''Tumor suppressor p53: Biology, signaling pathways, and therapeutic targeting.''; Biochim Biophys Acta Rev Cancer, 2021 PubMed Europe PMC Scholia
History
View all... |
External references
DataNodes
View all... |
Name | Type | Database reference | Comment |
---|---|---|---|
ACAD11 | GeneProduct | ENSG00000240303 (Ensembl Human) | |
ADGRB1 | GeneProduct | ENSG00000181790 (Ensembl Human) | |
ADORA2B | GeneProduct | ENSG00000170425 (Ensembl Human) | |
ALDH4A1 | GeneProduct | ENSG00000159423 (Ensembl Human) | |
APAF1 | GeneProduct | ENSG00000120868 (Ensembl Human) | |
Apoptosis | Pathway | ||
BAX | GeneProduct | ENSG00000087088 (Ensembl Human) | |
BBC3 | GeneProduct | ENSG00000105327 (Ensembl Human) | |
BTG2 | GeneProduct | ENSG00000159388 (Ensembl Human) | |
CCL2 | GeneProduct | ENSG00000108691 (Ensembl Human) | |
CCNG1 | GeneProduct | ENSG00000113328 (Ensembl Human) | |
CDKN1A | GeneProduct | ENSG00000124762 (Ensembl Human) | |
CPT1C | GeneProduct | ENSG00000169169 (Ensembl Human) | |
CX3CL1 | GeneProduct | ENSG00000006210 (Ensembl Human) | |
Cell Cycle Arrest | Pathway | ||
DDB2 | GeneProduct | ENSG00000134574 (Ensembl Human) | |
DNA Repair | Pathway | ||
DRAM1 | GeneProduct | ENSG00000136048 (Ensembl Human) | |
ERCC5 | GeneProduct | ENSG00000134899 (Ensembl Human) | |
FANCC | GeneProduct | ENSG00000158169 (Ensembl Human) | |
FAS | GeneProduct | ENSG00000026103 (Ensembl Human) | |
FUCA1 | GeneProduct | ENSG00000179163 (Ensembl Human) | |
Ferroptosis | Pathway | ||
GADD45A | GeneProduct | ENSG00000116717 (Ensembl Human) | |
GLS2 | GeneProduct | ENSG00000135423 (Ensembl Human) | |
GPX1 | GeneProduct | ENSG00000233276 (Ensembl Human) | |
ICAM1 | GeneProduct | ENSG00000090339 (Ensembl Human) | |
IRF5 | GeneProduct | ENSG00000128604 (Ensembl Human) | |
IRF9 | GeneProduct | ENSG00000213928 (Ensembl Human) | |
ISG15 | GeneProduct | ENSG00000187608 (Ensembl Human) | |
Invasion/Metastasis | Pathway | ||
LIF | GeneProduct | ENSG00000128342 (Ensembl Human) | |
MGMT | GeneProduct | ENSG00000170430 (Ensembl Human) | |
MIR145 | GeneProduct | ENSG00000276365 (Ensembl Human) | |
MIR200C | GeneProduct | ENSG00000207713 (Ensembl Human) | |
MIR34A | GeneProduct | ENSG00000284357 (Ensembl Human) | |
MIR34B/C | GeneProduct | ENSG00000207811/ENSG00000207562 (Ensembl Human) | |
MLH1 | GeneProduct | ENSG00000076242 (Ensembl Human) | |
MSH2 | GeneProduct | ENSG00000095002 (Ensembl Human) | |
Metabolism/Autophagy | Pathway | ||
NANOG | GeneProduct | ENSG00000111704 (Ensembl Human) | |
NCF2 | GeneProduct | ENSG00000116701 (Ensembl Human) | |
NOTCH1 | GeneProduct | ENSG00000148400 (Ensembl Human) | |
PERP | GeneProduct | ENSG00000112378 (Ensembl Human) | |
PIDD1 | GeneProduct | ENSG00000177595 (Ensembl Human) | |
PMAIP1 | GeneProduct | ENSG00000141682 (Ensembl Human) | |
PML | GeneProduct | ENSG00000140464 (Ensembl Human) | |
POLH | GeneProduct | ENSG00000170734 (Ensembl Human) | |
POLK | GeneProduct | ENSG00000122008 (Ensembl Human) | |
PRKAB1 | GeneProduct | ENSG00000111725 (Ensembl Human) | |
PRKAB2 | GeneProduct | ENSG00000131791 (Ensembl Human) | |
PTEN | GeneProduct | ENSG00000171862 (Ensembl Human) | |
PTPRV* | GeneProduct | ENSMUSG00000097993 (Ensembl) | MOUSE GENE |
RPRM | GeneProduct | ENSG00000177519 (Ensembl Human) | |
RRM2B | GeneProduct | ENSG00000048392 (Ensembl Human) | |
SAT1 | GeneProduct | ENSG00000130066 (Ensembl Human) | |
SERPINB5 | GeneProduct | ENSG00000206075 (Ensembl Human) | |
SERPINE1 | GeneProduct | ENSG00000106366 (Ensembl Human) | |
SESN1 | GeneProduct | ENSG00000080546 (Ensembl Human) | |
SESN2 | GeneProduct | ENSG00000130766 (Ensembl Human) | |
SIVA1 | GeneProduct | ENSG00000184990 (Ensembl Human) | |
SLC2A1 | GeneProduct | ENSG00000117394 (Ensembl Human) | |
SLC7A11 | GeneProduct | ENSG00000151012 (Ensembl Human) | |
SMR3B | GeneProduct | ENSG00000171201 (Ensembl Human) | |
Senescence | Pathway | ||
Stem Cell Function | Pathway | ||
THBS1 | GeneProduct | ENSG00000137801 (Ensembl Human) | |
TIGAR | GeneProduct | ENSG00000078237 (Ensembl Human) | |
TME | Pathway | ||
TNFRSF10D | GeneProduct | ENSG00000173530 (Ensembl Human) | |
TP53AIP1 | GeneProduct | ENSG00000120471 (Ensembl Human) | |
TP53I3 | GeneProduct | ENSG00000115129 (Ensembl Human) | |
TRAF4 | GeneProduct | ENSG00000076604 (Ensembl Human) | |
TRP53INP1* | GeneProduct | ENSMUSG00000028211 (Ensembl) | MOUSE GENE |
ULBP1 | GeneProduct | ENSG00000111981 (Ensembl Human) | |
ULBP2 | GeneProduct | ENSG00000131015 (Ensembl Human) | |
ULK1 | GeneProduct | ENSG00000177169 (Ensembl Human) | |
ULK2 | GeneProduct | ENSG00000083290 (Ensembl Human) | |
XPC | GeneProduct | ENSG00000154767 (Ensembl Human) | |
XRCC5 | GeneProduct | ENSG00000079246 (Ensembl Human) | |
YWHAB-208 | GeneProduct | ENST00000633979 (Ensembl Human) | |
ZMAT3 | GeneProduct | ENSG00000172667 (Ensembl Human) | |
p53 transcriptional regulation | Pathway |
Annotated Interactions
No annotated interactions