Electron transport chain (Drosophila melanogaster)

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Cytochrome COxidaseComplex IIIUncoupling Proteinbinds ATP Synthase betaComplex VATP Synthase MatrixComplex IIComplex IVNADH-UbiquinoneOxidoreductaseF1 ComplexIntermembraneSpaceAdenine NucleotideTranslocatorAssemblyUbiquinol-Cytochrome CReductaseSuccinate-UbiquinoneOxidoreductaseComplex IStalkC subunitF0 Complexmt:ATPase6ATPsynCF6LATPsyngammaH+CG3803ND-18blwCOX5Boxmt:ND4COX7A3ATPsynbetaATPsynFNDUFA3ATP5EScoxATPsynONDUFC2ND-B12ATPND-23NDUFC1SdhAe-COX4ND-B14.5AAnt2ATP5Ie-Ant2Ant2UQCR-14LND-24cypeATPsynDUbiquinoneUCP3e-mt:Cyt-bATPsyndeltaATPIF1NADHmt:CoIH2OND-B22mt:ND3ND-B14NDUFV3ATPsynCCOX7A2mt:CoIIIND-B8ATP8ND-30ND-19SdhDH+H+SdhBLNDUFB1CG14077ND-B17.2H+SuccinateUQCR-C2ND-75ND-13BCG14077CG6629FADND-SGDHND-49Lmt:CoIINDUFA1COX8ACOX7A2LATPsynGND-13ACOX7BATPsynCND-ACPUCP1ND-PDSWO2COX11NDUFS5ND-20LUcp4AATPsynBCOX5ACOX7A1ND-MLRQBmcpmt:ND2UQCR-C1TCA CycleND4LUQCR-11NDUFB4ND-42Cytochrome CATPsynCNAD+UCP2ND-B18UQCR-QCG40472H+COX7CND-51L2FADH2mt:ND1COX6BUQCRH+ND6CG9065H+mt:ND5ND-ASHIRFeSPSurf1NDUFB6CG10731ND-39


Description

An electron transport chain(ETC) couples a chemical reaction between an electron donor (such as NADH) and an electron acceptor (such as O2) to the transfer of H+ ions across a membrane, through a set of mediating biochemical reactions. These H+ ions are used to produce adenosine triphosphate (ATP), the main energy intermediate in living organisms, as they move back across the membrane.

In mitochondria, it is the conversion of oxygen to water, NADH to NAD+ and succinate to fumarate that drives the transfer of H+ ions.

Source: Wikipedia (wikipedia:Electron_transport_chain)

Comments

HomologyMapper 
This pathway was inferred from Homo sapiens pathway WP111 (r95118) with a 74.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
116915view11:57, 15 May 2021EweitzModified title
113954view06:21, 11 December 2020EgonwAnother clickable pathway
109401view16:47, 16 March 2020L DupuisFixed interaction
106092view12:00, 16 August 2019MaintBotHMDB identifier normalization
95792view14:40, 19 January 2018MkutmonHomology conversion update
71544view19:25, 17 October 2013MaintBotAutomated update of data sources
67192view10:19, 26 June 2013Christine ChichesterOntology Term : 'electron transport chain pathway' added !
62797view16:45, 2 May 2013MaintBotupdated uniprot data source
61894view03:41, 21 April 2013MaintBotupdated gpml version
40876view22:34, 1 March 2011MaintBotRemoved redundant pathway information and comments
38661view13:54, 23 September 2010FerryJagersLinked TCA Cycle
35637view20:03, 12 February 2010Khanspersupdated link
35636view19:56, 12 February 2010MaintBotConverted from Homo sapiens
35244view19:52, 11 February 2010AlexanderPicoModified description
21820view11:32, 14 November 2008MaintBot[[Pathway:Drosophila melanogaster:Electron Transport Chain]] moved to [[Pathway:WP542]]: Moved to stable identifier
8591view14:04, 7 January 2008MaintBotAdded to category $category
8589view14:04, 7 January 2008KdahlquistUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ATP5EGeneProductNo homologues found for original id L:514
ATP5IGeneProductNo homologues found for original id L:521
ATP8GeneProductNo homologues found for original id L:4509
ATPMetaboliteC00002 (KEGG Compound)
ATPIF1GeneProductNo homologues found for original id L:93974
ATPsynBGeneProductFBgn0019644 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:515
ATPsynCF6LGeneProductFBgn0035585 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:522
ATPsynCGeneProductFBgn0039830 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:518
ATPsynDGeneProductFBgn0016120 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:10476
ATPsynFGeneProductFBgn0035032 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:9551
ATPsynGGeneProductFBgn0010612 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:10632
ATPsynOGeneProductFBgn0016691 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:539
ATPsynbetaGeneProductFBgn0010217 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:506
ATPsyndeltaGeneProductFBgn0028342 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:513
ATPsyngammaGeneProductFBgn0020235 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:509
Ant2GeneProductFBgn0025111 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:291
BmcpGeneProductFBgn0036199 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:9016
CG10731GeneProductFBgn0034081 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:27109
CG14077GeneProductFBgn0036830 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:1339
CG3803GeneProductFBgn0034938 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:1355
CG40472GeneProductFBgn0085736 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4708
CG6629GeneProductFBgn0037860 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:6391
CG9065GeneProductFBgn0030610 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:10063
COX11GeneProductMultiple homologues found: En:FBgn0035995;En:FBgn0051648;
COX4GeneProductFBgn0032833 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:1327
COX5AGeneProductFBgn0019624 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:9377
COX5BGeneProductFBgn0031830 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:1329
COX6BGeneProductFBgn0031066 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:1340
COX7A1GeneProductNo homologues found for original id L:1346
COX7A2GeneProductNo homologues found for original id L:1347
COX7A2LGeneProductNo homologues found for original id L:9167
COX7A3GeneProduct
COX7BGeneProductNo homologues found for original id L:1349
COX7CGeneProduct
COX8AGeneProductNo homologues found for original id L:1351
Cytochrome CMetaboliteC00524 (KEGG Compound)
FADMetaboliteC00016 (KEGG Compound)
FADH2MetaboliteC01352 (KEGG Compound)
H+MetaboliteCHEBI:15378 (ChEBI)
H2OMetaboliteHMDB0002111 (HMDB)
NAD+MetaboliteC00003 (KEGG Compound)
NADHMetaboliteC00004 (KEGG Compound)
ND-13AGeneProductFBgn0031684 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4726
ND-13BGeneProductFBgn0047038 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4698
ND-18GeneProductFBgn0031021 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4724
ND-19GeneProductFBgn0035046 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4702
ND-20LGeneProductFBgn0039669 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:374291
ND-23GeneProductFBgn0017567 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4728
ND-24GeneProductFBgn0030853 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4729
ND-30GeneProductFBgn0266582 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4722
ND-39GeneProductFBgn0037001 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4704
ND-42GeneProductFBgn0019957 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4705
ND-49LGeneProductFBgn0039331 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4720
ND-51L2GeneProductFBgn0034007 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4723
ND-75GeneProductFBgn0017566 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4719
ND-ACPGeneProductFBgn0011361 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4706
ND-ASHIGeneProductFBgn0029888 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4714
ND-B12GeneProductFBgn0034645 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4709
ND-B14.5AGeneProductFBgn0025839 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4701
ND-B14GeneProductFBgn0033570 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4700
ND-B17.2GeneProductFBgn0031436 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:55967
ND-B18GeneProductFBgn0030605 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4713
ND-B22GeneProductFBgn0032511 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4715
ND-B8GeneProductFBgn0040705 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4695
ND-MLRQGeneProductFBgn0052230 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4697
ND-PDSWGeneProductFBgn0021967 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4716
ND-SGDHGeneProductFBgn0011455 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4711
ND4LGeneProductNo homologues found for original id L:4539
ND6GeneProductNo homologues found for original id L:4541
NDUFA1GeneProductNo homologues found for original id L:4694
NDUFA3GeneProductNo homologues found for original id L:4696
NDUFB1GeneProductNo homologues found for original id L:4707
NDUFB4GeneProductNo homologues found for original id L:4710
NDUFB6GeneProductNo homologues found for original id L:4712
NDUFC1GeneProductNo homologues found for original id L:4717
NDUFC2GeneProductNo homologues found for original id L:4718
NDUFS5GeneProductNo homologues found for original id L:4725
NDUFV3GeneProductNo homologues found for original id L:4731
O2MetaboliteHMDB0001377 (HMDB)
RFeSPGeneProductFBgn0021906 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:7386
ScoxGeneProductFBgn0262467 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:6341
SdhAGeneProductFBgn0261439 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:6389
SdhBLGeneProductFBgn0030975 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:6390
SdhDGeneProductFBgn0039112 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:6392
SuccinateMetaboliteC00042 (KEGG Compound)
Surf1GeneProductFBgn0029117 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:6834
TCA CyclePathwayWP78 (WikiPathways)
UCP1GeneProductNo homologues found for original id L:7350
UCP2GeneProductNo homologues found for original id L:7351
UCP3GeneProductNo homologues found for original id L:7352
UQCRGeneProductNo homologues found for original id L:10975
UQCR-11GeneProductFBgn0260008 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:7388
UQCR-14LGeneProductFBgn0039576 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:7381
UQCR-C1GeneProductFBgn0038271 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:7384
UQCR-C2GeneProductFBgn0250814 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:7385
UQCR-QGeneProductFBgn0036728 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:27089
UbiquinoneMetaboliteHMDB0002012 (HMDB)
Ucp4AGeneProductFBgn0030872 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:9481
blwGeneProductFBgn0011211 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:498
cypeGeneProductFBgn0015031 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:1345
e-MetaboliteC05359 (KEGG Compound)
mt:ATPase6GeneProductFBgn0013672 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4508
mt:CoIGeneProductFBgn0013674 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4512
mt:CoIIGeneProductFBgn0013675 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4513
mt:CoIIIGeneProductFBgn0013676 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4514
mt:Cyt-bGeneProductFBgn0013678 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4519
mt:ND1GeneProductFBgn0013679 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4535
mt:ND2GeneProductFBgn0013680 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4536
mt:ND3GeneProductFBgn0013681 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4537
mt:ND4GeneProductFBgn0262952 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4538
mt:ND5GeneProductFBgn0013684 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:4540
oxGeneProductFBgn0011227 (Ensembl) Homology Mapping from Homo sapiens to Drosophila melanogaster: Original ID = L:29796

Annotated Interactions

No annotated interactions
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