Regulation of actin cytoskeleton (Pan troglodytes)

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Actin polymerizationstress fiberActin polymerization-pFocal adhesionassemblyGPCRFocal complexassembly?RTKPI3KGene ExpressionChemotatic factorActin polymerization+pstress fiberGrowth Factor (GF)GFStabilizationof actinRASRASPI3KActomyosinassembly contractionLamellipodiaGPCRRTKFilipodiaChemotactic factorFGF3APCPIP3LOC468536RASSF7SSH3FGFR4MAP2K1EGFRDOCK1FGF21PIP5K1BRAF1SOS2BradykininPAK4RAC2FGF17ACTG1FGF11KRASPDGFRAFGF6DIAP3GNA13CFL1ARHGEF6VIL1PIK3CDMAPK3RRAS2FGF7FGF9Focal AdhesionpathwayFGF23PIK3C3PAK7PIK3R3PIP2PIK3C2BFGF5CFL2FGF10BAIAP2PIK3R1PIK3C2GTMSB4XLOC470938FGF15PIP4K2AARHGEF6WASFGFR3FGF14ABI2CHRM5PIP2ACTG1RAC1P4PDGFRBFGF1GNA12EGFPIK3R2CHRM2PAK3F2RF2FGFR2LOC100611792PIP4K2CNRASFGF13LOC748477PAK2ARPC5PIP5KL1ENAHVCLPIK3CGFGFR1PIP4K2BSLC9A1Focal AdhesionpathwayWASF2INS2FGF12CHRM1PDGFAFGF20MYH10DIAP1GSNCYFIP2PIK3R4BDKRB2RRASFGF2Adherens junctionpathwayITGA1FGF16FGF22PTK2LOC442775PPP1R12ALOC456157VCLLOC465655PAK1PXNPDGFBARHGEF7ARHGEF1MYLKMAPK1NCKAP1ACTBVAV1MYL1MOSCDC42CHRM4LIMK1CHRM3PIK3CBPIK3R5C3orf10PIP5K1AAcetylcholineARHGEF4RDXPAK6LOC741907ROCK1LOC100609242RHOAACTN1MSNFGF4BAIAP2WASF1RAC3MAPK SignalingpathwayPIK3C2AApc2SOS1ACTBGIT1BCAR1EZRCRKCD14ROCK2PIP4K2ABRAFACTBLOC748477SSH1FGF8FN1INS1ARPC5PIP5K1CACTG1LOC460327PIK3CAMAPK6FGF18SSH2CSKIQGAP1LPSBDKRB1


Description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP51(r45278) with a 80% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
128551view04:35, 12 February 2024EweitzModified title
114262view13:59, 2 January 2021EgonwThree more pathways clickable
72131view07:57, 25 October 2013Mkutmonadded datasource to pathway datanodes
71673view19:41, 17 October 2013MaintBotAutomated update of data sources
69266view18:38, 8 July 2013MaintBotUpdated to 2013 gpml schema
48143view18:34, 9 May 2012MaintBotUpdating from human to fix xrefs
41574view02:00, 2 March 2011MaintBotRemoved redundant pathway information and comments
34302view22:05, 9 December 2009MaintBotAutomatic update of empty xrefs
33594view09:54, 1 December 2009MaintBotRemoved group label
31614view22:15, 13 August 2009MaintBotFixed text labels
30513view21:46, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ABI2GeneProduct459892 (Entrez Gene)
ACTBGeneProduct450133 (Entrez Gene)
ACTG1GeneProduct
ACTN1GeneProduct452993 (Entrez Gene)
APCGeneProduct461999 (Entrez Gene)
ARHGEF1GeneProduct
ARHGEF4GeneProduct470538 (Entrez Gene)
ARHGEF6GeneProduct
ARHGEF7GeneProduct452673 (Entrez Gene)
ARPC5GeneProduct457574 (Entrez Gene)
AcetylcholineMetabolite51-84-3 (CAS)
Adherens junction pathwayPathway
Apc2GeneProduct
BAIAP2GeneProduct454951 (Entrez Gene)
BCAR1GeneProduct454246 (Entrez Gene)
BDKRB1GeneProduct100612769 (Entrez Gene)
BDKRB2GeneProduct467547 (Entrez Gene)
BRAFGeneProduct463781 (Entrez Gene)
BradykininMetabolite58-82-2 (CAS)
C3orf10GeneProduct
CD14GeneProduct462118 (Entrez Gene)
CDC42GeneProduct
CFL1GeneProduct745772 (Entrez Gene)
CFL2GeneProduct452853 (Entrez Gene)
CHRM1GeneProduct451272 (Entrez Gene)
CHRM2GeneProduct463758 (Entrez Gene)
CHRM3GeneProduct469725 (Entrez Gene)
CHRM4GeneProduct
CHRM5GeneProduct503515 (Entrez Gene)
CRKGeneProduct747142 (Entrez Gene)
CSKGeneProduct453745 (Entrez Gene)
CYFIP2GeneProduct462221 (Entrez Gene)
DIAP1GeneProduct
DIAP3GeneProduct
DOCK1GeneProduct
EGFGeneProduct461435 (Entrez Gene)
EGFRGeneProduct463415 (Entrez Gene)
ENAHGeneProduct
EZRGeneProduct463100 (Entrez Gene)
F2GeneProduct451158 (Entrez Gene)
F2RGeneProduct471510 (Entrez Gene)
FGF10GeneProduct471553 (Entrez Gene)
FGF11GeneProduct748965 (Entrez Gene)
FGF12GeneProduct471041 (Entrez Gene)
FGF13GeneProduct465886 (Entrez Gene)
FGF1GeneProduct462158 (Entrez Gene)
FGF14GeneProduct739338 (Entrez Gene)
FGF15GeneProduct
FGF16GeneProduct473676 (Entrez Gene)
FGF17GeneProduct472708 (Entrez Gene)
FGF18GeneProduct
FGF20GeneProduct739665 (Entrez Gene)
FGF21GeneProduct468948 (Entrez Gene)
FGF22GeneProduct
FGF23GeneProduct747164 (Entrez Gene)
FGF2GeneProduct641462 (Entrez Gene)
FGF3GeneProduct466693 (Entrez Gene)
FGF4GeneProduct747727 (Entrez Gene)
FGF5GeneProduct471190 (Entrez Gene)
FGF6GeneProduct747181 (Entrez Gene)
FGF7GeneProduct744975 (Entrez Gene)
FGF8GeneProduct
FGF9GeneProduct744731 (Entrez Gene)
FGFR1GeneProduct464122 (Entrez Gene)
FGFR2GeneProduct466220 (Entrez Gene)
FGFR3GeneProduct461067 (Entrez Gene)
FGFR4GeneProduct462301 (Entrez Gene)
FN1GeneProduct459926 (Entrez Gene)
Focal Adhesion pathwayPathwayWP306 (WikiPathways)
GIT1GeneProduct454549 (Entrez Gene)
GNA12GeneProduct463234 (Entrez Gene)
GNA13GeneProduct454827 (Entrez Gene)
GSNGeneProduct464706 (Entrez Gene)
INS1GeneProduct
INS2GeneProduct
IQGAP1GeneProduct467762 (Entrez Gene)
ITGA1GeneProduct461880 (Entrez Gene)
KRASGeneProduct473387 (Entrez Gene)
LIMK1GeneProduct463466 (Entrez Gene)
LOC100609242GeneProduct100609242 (Entrez Gene)
LOC100611792GeneProduct100611792 (Entrez Gene)
LOC442775GeneProduct
LOC456157GeneProduct456157 (Entrez Gene)
LOC460327GeneProduct460327 (Entrez Gene)
LOC465655GeneProduct465655 (Entrez Gene)
LOC468536GeneProduct468536 (Entrez Gene)
LOC470938GeneProduct470938 (Entrez Gene)
LOC741907GeneProduct741907 (Entrez Gene)
LOC748477GeneProduct748477 (Entrez Gene)
LPSMetaboliteC00338 (KEGG Compound)
MAP2K1GeneProduct450188 (Entrez Gene)
MAPK Signaling pathwayPathwayWP382 (WikiPathways)
MAPK1GeneProduct458680 (Entrez Gene)
MAPK3GeneProduct454037 (Entrez Gene)
MAPK6GeneProduct453439 (Entrez Gene)
MOSGeneProduct472772 (Entrez Gene)
MSNGeneProduct
MYH10GeneProduct455090 (Entrez Gene)
MYL1GeneProduct459915 (Entrez Gene)
MYLKGeneProduct460640 (Entrez Gene)
NCKAP1GeneProduct459801 (Entrez Gene)
NRASGeneProduct742713 (Entrez Gene)
PAK1GeneProduct451439 (Entrez Gene)
PAK2GeneProduct460965 (Entrez Gene)
PAK3GeneProduct450118 (Entrez Gene)
PAK4GeneProduct
PAK6GeneProduct453327 (Entrez Gene)
PAK7GeneProduct469876 (Entrez Gene)
PDGFAGeneProduct
PDGFBGeneProduct458844 (Entrez Gene)
PDGFRAGeneProduct
PDGFRBGeneProduct462188 (Entrez Gene)
PIK3C2AGeneProduct451052 (Entrez Gene)
PIK3C2BGeneProduct457657 (Entrez Gene)
PIK3C2GGeneProduct
PIK3C3GeneProduct455385 (Entrez Gene)
PIK3CAGeneProduct460858 (Entrez Gene)
PIK3CBGeneProduct
PIK3CDGeneProduct457922 (Entrez Gene)
PIK3CGGeneProduct463649 (Entrez Gene)
PIK3R1GeneProduct461836 (Entrez Gene)
PIK3R2GeneProduct455855 (Entrez Gene)
PIK3R3GeneProduct456565 (Entrez Gene)
PIK3R4GeneProduct460692 (Entrez Gene)
PIK3R5GeneProduct455085 (Entrez Gene)
PIP2MetaboliteC04637 (KEGG Compound)
PIP3MetaboliteC05981 (KEGG Compound)
PIP4K2AGeneProduct742458 (Entrez Gene)
PIP4K2BGeneProduct746830 (Entrez Gene)
PIP4K2CGeneProduct467044 (Entrez Gene)
PIP5K1AGeneProduct457288 (Entrez Gene)
PIP5K1BGeneProduct464513 (Entrez Gene)
PIP5K1CGeneProduct455590 (Entrez Gene)
PIP5KL1GeneProduct464758 (Entrez Gene)
PPP1R12AGeneProduct452095 (Entrez Gene)
PTK2GeneProduct464422 (Entrez Gene)
PXNGeneProduct452303 (Entrez Gene)
RAC1P4GeneProduct
RAC2GeneProduct
RAC3GeneProduct
RAF1GeneProduct460182 (Entrez Gene)
RASSF7GeneProduct466303 (Entrez Gene)
RDXGeneProduct466776 (Entrez Gene)
RHOAGeneProduct461014 (Entrez Gene)
ROCK1GeneProduct455326 (Entrez Gene)
ROCK2GeneProduct470307 (Entrez Gene)
RRAS2GeneProduct451038 (Entrez Gene)
RRASGeneProduct468955 (Entrez Gene)
SLC9A1GeneProduct456669 (Entrez Gene)
SOS1GeneProduct459171 (Entrez Gene)
SOS2GeneProduct452897 (Entrez Gene)
SSH1GeneProduct467124 (Entrez Gene)
SSH2GeneProduct454551 (Entrez Gene)
SSH3GeneProduct451365 (Entrez Gene)
TMSB4XGeneProduct
VAV1GeneProduct455647 (Entrez Gene)
VCLGeneProduct450531 (Entrez Gene)
VIL1GeneProduct470646 (Entrez Gene)
WASGeneProduct
WASF1GeneProduct462935 (Entrez Gene)
WASF2GeneProduct456675 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP944"
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