mRNA processing (Gallus gallus)

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1U2AFASF3b14bYYYYCstFUGAGAG5'U2 snRNPP-exon 1CF Isplicing factor SF3BSerine/Argenine Rich Proteins(SR)Formation of the Spliceosomal B complexPoly(A)pb II5'intronNote: New participating members shown at each stepU2 snRNPshnRNPsCF IISR-repressor proteinsInternal methylation of mRNACPSFCstF3'SR-proteins35Formation of the Spliceosomal E complexMisc.U4/U6PRNAi pathwayMethylation of mRNA3'Spt5SR-phosphatases5'U2AF3'Poly(A)-binding protein IIexon 2exon 2Additional SR proteins(2c)5'Formation of the active Spliceosomal C complexInternal methylation of mRNAsplicesome associated helicasesFormation of pre-mRNPs3'AGYYYYsnRNP Sm core complexsnRNP Sm core complexRegulation ofAlternative SplicingU1 snRNPmRNA capping(1)5'U6 snRNPsnRNP Sm core complexAAGPoly(A) polymerase alphaAAAAAAARNA helicase AU2 snRNPexon 1SR-proteinsFormation of pre-mRNPs5' G capFormation of the Spliceosomal E complex(2a)RNA helicaseFormation of the Spliceosomal C complexU6U4:U5:U6 tri-snRNP complexexon 2U4SR protein phosphatasesexon 1Rngtt (capping enzyme)U2hnRNP regulatorsSR-binding sitesmRNA splicing (major pathway)U5exon 2CF IISR protein kinases(2)U1Cleavage at the 3'-Splice-Site and Exon Ligationright click on blue text for detailed informationPutative Alternative SplicingRegulatorsUG3'CPSFPiSR-binding sitesFormation of the Spliceosomal A complexSR-proteinsexon 2mRNA splice site selectionA3'degraded5'AGexon 23'AGAccessory ProteinsmRNA Cappingsplicing factor SF3A(2b)Poly(A) polYYYYRnmt (methyltransferase)AAUAAACFIU4 snRNPCleavage of mRNA at the 3'-endpre-mRNASR-kinasesAdditional Factors65mRNA 3'-end processingexon 1Additional FactorsACAiPo5'exon 15'Polr2a5'Cap BindingProcessing of Intron-Containing Pre-mRNAYYYYPrimary RNA transcriptFormation of the Spliceosomal A complex(3)exon 1U5 snRNPFormation of the Spliceosomal B complexYYYY3'YYYYAGU3'Additional FactorsmRNA polyadenylation3'heterogeneous nuclear ribonucleoproteins3'A5'5'Kinases Phosphorylating RS domains?U1 snRNPU5Lariat Formation and 5'-Splice Site CleavageSRSF3SUGP1NONOTRA2BPCBP2SNRPECPSF4CDC40DHX38U2AF1SNRPD3SF3A2SMC1L1DDX20HNRNPABSREK1CDC40SRSF1DNAJC8RNPS1CSTF1RBM17DHX15FUSRBM5SRSF5DDX1CSTF2SNRPALSM2SF3B1SRPK2CSTF3DHX8PAPOLAXRN2PTBP2HNRPCDHX9SNU13PHF5AU2AF2SF3A3POLR2ASRSF7SF3B3PRPF3HNRNPMSNRPBRnu6CELF4U4 snRNAMETTL3SF3A1SPOPRBMXSF3B5CD2BP2NCBP2SFRS16SRPK1PPM1GSNU13HNRNPKPRPF8SFRS2CPSF3SNRPA1RNGTTYBX1SF3B4PRPF4HNRNPH1CPSF2SRP54HRMT1L2HNRNPH1CLK2DHX16RNMTPABPN1LSM2EFTUD2PSKH1SUGP2HNRPA3P1HNRPA1U1 snRNACLP1U5 snRNASRRM1ATPGMPPRPF4SNRNP70SFRS9HNRNPRSNRPB2SNRPBSNRNP40HRMT1L1PRPF6TXNL4ALSM7CLK4SNRPD2CLK3SNU13RNU2HNRNPUHNRNPA2B1SUPT5HSNRPFRBM39PRPF18CSTF2TCPSF1NCBP1SFPQSNRPGPTBP1DICER1SRSF10SFRS4SRSF6PRPF8TMED10PRPF40ASRSF10SNRPD1SFSWAPNXF1SNRPBCLK1CELF1HNRNPDHNRPLCELF2NUDT21SF3B2PRPF4B


Description

This process describes the conversion of precursor messenger RNA into mature messenger RNA (mRNA).

The pre-mRNA molecule undergoes three main modifications. These modifications are 5' capping, 3' polyadenylation, and RNA splicing, which occur in the cell nucleus before the RNA is translated.

5' Capping: Capping of the pre-mRNA involves the addition of 7-methylguanosine (m7G) to the 5' end. The cap protects the 5' end of the primary RNA transcript from attack by ribonucleases that have specificity to the 3'5' phosphodiester bonds.

3' Processing: The pre-mRNA processing at the 3' end of the RNA molecule involves cleavage of its 3' end and then the addition of about 200 adenine residues to form a poly(A) tail. As the poly(A) tails is synthesised, it binds multiple copies of poly(A) binding protein, which protects the 3'end from ribonuclease digestion.

Splicing: RNA splicing is the process by which introns, regions of RNA that do not code for protein, are removed from the pre-mRNA and the remaining exons connected to re-form a single continuous molecule.

Description adapted from Wikipedia: http://en.wikipedia.org/wiki/Post-transcriptional_modification

Pathway adapted from http://www.reactome.org.

Comments

HomologyMapper 
This pathway was inferred from Homo sapiens pathway WP411 (r95128) with a 83.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Carmody SR, Wente SR; ''mRNA nuclear export at a glance.''; J Cell Sci, 2009 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
117212view09:27, 19 May 2021EweitzModified title
95767view14:20, 19 January 2018MkutmonHomology conversion update
74233view16:36, 8 April 2014EgonwRemoved a data source where no ID was given.
68842view17:19, 8 July 2013MaintBotUpdated to 2013 gpml schema
67501view11:10, 26 June 2013DdiglesOntology Term : 'spliceosome pathway' added !
47783view05:56, 6 April 2012Khanspersupdated xref
40980view22:55, 1 March 2011MaintBotRemoved redundant pathway information and comments
35264view20:21, 11 February 2010KhanspersAdded xrefs for GMP and ATP
35259view20:17, 11 February 2010KhanspersModified description
33904view18:01, 9 December 2009MaintBotAutomatic update of empty xrefs
33471view15:05, 30 November 2009MaintBotRemoved group label
31521view21:40, 13 August 2009MaintBotFixed text labels
30362view20:56, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ATPMetabolite1927-31-7 (CAS)
CD2BP2GeneProductNo homologues found for original id L:10421
CDC40GeneProductENSGALG00000015061 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:51362
CELF1GeneProductENSGALG00000008097 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10658
CELF2GeneProductENSGALG00000034590 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10659
CELF4GeneProductENSGALG00000002413 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:56853
CLK1GeneProductENSGALG00000028438 (Ensembl)
  • PMID: 15010457: Inhibitor John C. Bell, PhD

    Professor, Depts. of Medicine and Biochemistry, Microbiology & Immunology University of Ottawa Career Scientist, Ottawa Regional Cancer Centre Associate Scientist, The Ottawa Hospital Research Institute Telephone: 613-737-7700 ext 6893 Fax: 613-247-3524 Email: [email protected] The control of pre-mRNA splicing by the Clk kinase family

    We are studying a family of kinases which we believe provide an interface between intracellular signaling networks and the post-transcriptional mechanism of mRNA splicing. We are performing a structure:function analysis of the three Clk family members to identify domains in the three proteins which are involved in regulating splicing. Using homologous recombination we are generating null strains of mice which are lacking one, two or all three Clk genes. The Clk kinases all possess dual specificity kinase activity and yeast expression systems are being used to produce large amounts of the kinase to perform a detailed analysis of the sites of serine, threonine and tyrosine autophosphorylation within the kinase.
  • Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:1195
CLK2GeneProductENSGALG00000029444 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:1196
CLK3GeneProductENSGALG00000001362 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:1198
CLK4GeneProductENSGALG00000006057 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:57396
CLP1GeneProductENSGALG00000007370 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10978
CPSF1GeneProductNo homologues found for original id L:29894
CPSF2GeneProductENSGALG00000010783 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:53981
CPSF3GeneProductENSGALG00000016424 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:51692
CPSF4GeneProductENSGALG00000004714 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10898
CSTF1GeneProductENSGALG00000007757 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:1477
CSTF2GeneProductENSGALG00000006760 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:1478
CSTF2TGeneProductENSGALG00000006760 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:23283
CSTF3GeneProductENSGALG00000011685 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:1479
DDX1GeneProductENSGALG00000016461 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:1653
DDX20GeneProductENSGALG00000001504 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:11218
DHX15GeneProductENSGALG00000014395 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:1665
DHX16GeneProductENSGALG00000029334 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:8449
DHX38GeneProductENSGALG00000000787 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:9785
DHX8GeneProductENSGALG00000032305 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:1659
DHX9GeneProductNo homologues found for original id L:1660
DICER1GeneProductENSGALG00000010999 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:23405
DNAJC8GeneProductENSGALG00000000790 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:22826
EFTUD2GeneProductENSGALG00000000988 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:9343
FUSGeneProductENSGALG00000032219 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:2521
GMPMetabolite85-32-5 (CAS)
HNRNPA2B1GeneProductENSGALG00000011036 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:3181
HNRNPABGeneProductENSGALG00000014381 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:3182
HNRNPDGeneProductENSGALG00000011184 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:3184
HNRNPH1GeneProductENSGALG00000031120 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:3187
HNRNPKGeneProductENSGALG00000012591 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:3190
HNRNPMGeneProductENSGALG00000000377 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:4670
HNRNPRGeneProductENSGALG00000000814 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10236
HNRNPUGeneProductENSGALG00000010671 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:3192
HNRPA1GeneProductENSGALG00000042011 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:3178
HNRPA3P1GeneProduct
HNRPCGeneProductNo homologues found for original id L:3183
HNRPLGeneProductENSGALG00000043929 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:3191
HRMT1L1GeneProductNo homologues found for original id L:3275
HRMT1L2GeneProductNo homologues found for original id L:3276
LSM2GeneProductNo homologues found for original id L:57819
LSM7GeneProductENSGALG00000000408 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:51690
METTL3GeneProductENSGALG00000044213 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:56339
NCBP1GeneProductENSGALG00000002087 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:4686
NCBP2GeneProductENSGALG00000006843 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:22916
NONOGeneProductENSGALG00000005507 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:4841
NUDT21GeneProductENSGALG00000003084 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:11051
NXF1GeneProductENSGALG00000032057 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10482
PABPN1GeneProductNo homologues found for original id L:8106
PAPOLAGeneProductENSGALG00000030578 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10914
PCBP2GeneProductNo homologues found for original id L:5094
PHF5AGeneProductENSGALG00000011953 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:84844
POLR2AGeneProductENSGALG00000032698 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5430
PPM1GGeneProductENSGALG00000016513 (Ensembl)
  • PMID: 12773558
  • Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5496
PRPF18GeneProductENSGALG00000043593 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:8559
PRPF3GeneProductENSGALG00000028205 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:9129
PRPF40AGeneProductENSGALG00000012526 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:55660
PRPF4BGeneProductENSGALG00000043751 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:8899
PRPF4GeneProductENSGALG00000008857 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:9128
PRPF6GeneProductENSGALG00000006001 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:24148
PRPF8GeneProductENSGALG00000002943 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10594
PSKH1GeneProductENSGALG00000001647 (Ensembl)
  • PMID: 12466556
  • Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5681
PTBP1GeneProductENSGALG00000001962 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5725
PTBP2GeneProductENSGALG00000005552 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:58155
RBM17GeneProductENSGALG00000006332 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:84991
RBM39GeneProductENSGALG00000001550 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:9584
RBM5GeneProductENSGALG00000039288 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10181
RBMXGeneProductENSGALG00000006457 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:27316
RNGTTGeneProductENSGALG00000015787 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:8732
RNMTGeneProductENSGALG00000013889 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:8731
RNPS1GeneProductENSGALG00000009288 (Ensembl)
  • PMID: 14729963
  • Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10921
RNU2GeneProduct
  • GenBank sequence: K00027
  • No homologues found for original id L:6066
Rnu6RnaGenBank sequence: M10329
SF3A1GeneProductENSGALG00000007937 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10291
SF3A2GeneProductENSGALG00000021679 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:8175
SF3A3GeneProductENSGALG00000001540 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10946
SF3B1GeneProductENSGALG00000008038 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:23451
SF3B2GeneProductNo homologues found for original id L:10992
SF3B3GeneProductENSGALG00000037508 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:23450
SF3B4GeneProductENSGALG00000013352 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10262
SF3B5GeneProductENSGALG00000030824 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:83443
SFPQGeneProductENSGALG00000002514 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6421
SFRS16GeneProductNo homologues found for original id L:11129
SFRS2GeneProductNo homologues found for original id L:6427
SFRS4GeneProductENSGALG00000037539 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6429
SFRS9GeneProduct
  • PMID: 12738786, PMID: 12024014 (associated with hnRNP A1 splicing)
  • No homologues found for original id L:8683
SFSWAPGeneProductENSGALG00000002487 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6433
SMC1L1GeneProductENSGALG00000041777 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:8243
SNRNP40GeneProductENSGALG00000000615 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:9410
SNRNP70GeneProductENSGALG00000034738 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6625
SNRPAGeneProductNo homologues found for original id L:6626
SNRPA1GeneProductENSGALG00000007170 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6627
SNRPB2GeneProductENSGALG00000026999 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6629
SNRPBGeneProductENSGALG00000035421 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6628
SNRPD1GeneProductENSGALG00000041334 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6632
SNRPD2GeneProductENSGALG00000042282 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6633
SNRPD3GeneProductENSGALG00000006596 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6634
SNRPEGeneProductNo homologues found for original id L:6635
SNRPFGeneProductENSGALG00000011409 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6636
SNRPGGeneProductENSGALG00000028409 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6637
SNU13GeneProductENSGALG00000011931 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:4809
SPOPGeneProductENSGALG00000009939 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:8405
SREK1GeneProductENSGALG00000014775 (Ensembl)
  • PMID: 14559993. SRrp86 is a unique member of the SR protein superfamily containing one RNA recognition motif and two serine-arginine (SR)-rich domains separated by an unusual glutamic acid-lysine (EK)-rich region. Previously, we showed that SRrp86 could regulate alternative splicing by both positively and negatively modulating the activity of other SR proteins and that the unique EK domain could inhibit both constitutive and alternative splicing. These functions were most consistent with the model in which SRrp86 functions by interacting with and thereby modulating the activity of target proteins. To identify the specific proteins that interact with SRrp86, we used a yeast two-hybrid library screen and immunoprecipitation coupled to mass spectrometry. We show that SRrp86 interacts with all of the core SR proteins, as well as a subset of other splicing regulatory proteins, including SAF-B, hnRNP G, YB-1, and p72. In contrast to previous results that showed activation of SRp20 by SRrp86, we now show that SAF-B, hnRNP G, and 9G8 all antagonize the activity of SRrp86. Overall, we conclude that not only does SRrp86 regulate SR protein activity but that it is, in turn, regulated by other splicing factors to control alternative splice site selection.
  • Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:140890
SRP54GeneProductENSGALG00000023135 (Ensembl)
  • PMID: 14729963
  • Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6729
SRPK1GeneProductENSGALG00000037546 (Ensembl)
  • PMID: 12773558
  • Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6732
SRPK2GeneProductENSGALG00000008154 (Ensembl)
  • PMID: 12773558
  • Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6733
SRRM1GeneProductENSGALG00000001283 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10250
SRSF10GeneProductENSGALG00000004133 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10772
SRSF1GeneProductENSGALG00000005525 (Ensembl)
  • Antagonist splicing factor
  • Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6426
SRSF3GeneProductENSGALG00000000533 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6428
SRSF5GeneProductENSGALG00000009421 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6430
SRSF6GeneProductENSGALG00000000990 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6431
SRSF7GeneProductENSGALG00000033120 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6432
SUGP1GeneProductENSGALG00000042132 (Ensembl)
  • inferred from: SURP 2, G patch protein, UniProt:O60378
  • Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:57794
SUGP2GeneProductENSGALG00000003047 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10147
SUPT5HGeneProductENSGALG00000039160 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6829
TMED10GeneProductENSGALG00000010318 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10972
TRA2BGeneProductENSGALG00000006531 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6434
TXNL4AGeneProductENSGALG00000040739 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10907
U1 snRNARnaGenBank sequence: J00645
U2AF1GeneProductENSGALG00000016198 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:7307
U2AF2GeneProductNo homologues found for original id L:11338
U4 snRNARnaGenBank sequence: M10328, M18004
U5 snRNARnaGenBank sequence: AB021173
XRN2GeneProductENSGALG00000008372 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:22803
YBX1GeneProductENSGALG00000004848 (Ensembl) Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:4904

Annotated Interactions

No annotated interactions
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