De novo biosynthesis of pyrimidine deoxyribonucleotides (Saccharomyces cerevisiae)
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reduced thioredoxin
oxidized thioredoxin
H2O
UDP
reduced flavodoxin
H2O
H2O
H2O
7,8-dihydrofolate
dUDP
dTTP
CTP
oxidized flavodoxin
UTP
oxidized thioredoxin
oxidized flavodoxin
reduced thioredoxin
dUTP
H2O
H2O
NH3
RNR2
dCTP
dTMP
RNR4
5,10-methylene-THF
RNR3
CDC8
ATP
RNR1
ATP
ADP
RNR4
RNR1
DUT1
ADP
ADP
CDP
RNR2
ATP
dCMP
YNK1
dUMP
ADP
pyrophosphate
ATP
YNK1
RNR3
dUMP
CDC8
ADP
ATP
dCDP
CDC21
dTDP
Description
No description
Comments
GenMAPP remarks
Based on
http://pathway.yeastgenome.org/biocyc/
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Quality Tags
Ontology Terms
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Bibliography
''de novo biosynthesis of pyrimidine deoxyribonucleotides''; YeastGenome,
History
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Compare
Revision
Action
Time
User
Comment
135637
view
04:54, 8 October 2024
Khanspers
Ontology Term : 'classic metabolic pathway' added !
135636
view
04:50, 8 October 2024
Khanspers
removed GenMAPP comments and updated reference
135635
view
04:49, 8 October 2024
Khanspers
Modified description
135634
view
04:48, 8 October 2024
Khanspers
overhaul
124941
view
06:57, 3 January 2023
Egonw
More metabolites as DataNode and connected lines
117280
view
10:46, 20 May 2021
Eweitz
Modified title
107020
view
13:47, 17 September 2019
MaintBot
HMDB identifier normalization
87228
view
14:47, 19 July 2016
Susan
Ontology Term : 'de novo pyrimidine biosynthetic pathway' added !
87227
view
14:47, 19 July 2016
Susan
Ontology Term : 'PW:0000861' removed !
87225
view
14:44, 19 July 2016
Susan
Ontology Term : 'pyrimidine biosynthetic pathway' added !
72053
view
17:07, 24 October 2013
Mkutmon
updated annotation for pyrophosphate
69864
view
17:26, 11 July 2013
Egonw
Marked a few DataNodes with CAS registry numbers as metabolites.
69612
view
20:33, 8 July 2013
MaintBot
Updated to 2013 gpml schema
41845
view
04:50, 2 March 2011
MaintBot
Removed redundant pathway information and comments
20753
view
11:29, 14 November 2008
MaintBot
[[Pathway:Saccharomyces cerevisiae:De Novo Biosynthesis of Pyrimidine Deoxyribonucleotides]] moved to [[Pathway:WP36]]: Moved to stable identifier
12684
view
07:57, 17 May 2008
MaintBot
automated metabolite conversion
8687
view
14:06, 7 January 2008
MaintBot
Added to category $category
8685
view
14:06, 7 January 2008
M.Braymer
Uploaded new pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
5,10-methylene-THF
Metabolite
31690-11-6 (CAS)
ADP
Metabolite
58-64-0 (CAS)
ATP
Metabolite
1927-31-7 (CAS)
CDC21
GeneProduct
S000005600 (SGD)
CDC8
GeneProduct
S000003818 (SGD)
CDP
Metabolite
63-38-7 (CAS)
DUT1
GeneProduct
S000000456 (SGD)
RNR1
GeneProduct
S000000872 (SGD)
RNR2
GeneProduct
S000003563 (SGD)
RNR3
GeneProduct
S000001328 (SGD)
RNR4
GeneProduct
S000003412 (SGD)
YNK1
GeneProduct
S000001550 (SGD)
dCDP
Metabolite
800-73-7 (CAS)
dCMP
Metabolite
1032-65-1 (CAS)
dCTP
Metabolite
2056-98-6 (CAS)
dTDP
Metabolite
491-97-4 (CAS)
dTMP
Metabolite
365-07-1 (CAS)
dUMP
Metabolite
964-26-1 (CAS)
pyrophosphate
Metabolite
HMDB0000250 (HMDB)
Annotated Interactions
No annotated interactions
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