Signal transduction of S1P receptor (Mus musculus)

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GPCRs similar to S1PMapk7Edg8Gnai3Plcb3Mapk12Smpd2Mapk1Edg5Gnai1Edg1Gnai2Akt3Edg3Asah2Akt1Pik3c2gSphk1Sphk2Akt2Mapk6Racgap1Mapk3


Description

This is a representation of figure 2 from T. Hla, et al. 2001, Science, 294, pg. 1877.

Sphingosine-1-phosphate (S1P) is a signaling sphingolipid, also known as lysosphingolipid. It is also referred to as a bioactive lipid mediator. Sphingolipids at large form a class of lipids characterized by a particular aliphatic aminoalcohol, which is sphingosine.

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Bibliography

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History

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CompareRevisionActionTimeUserComment
117945view10:45, 23 May 2021EweitzModified title
94903view21:03, 12 October 2017Khanspersconnected interaction
94819view02:51, 6 October 2017KhanspersModified description
94818view02:48, 6 October 2017Khanspersremoved old GenMAPP comments
94817view02:43, 6 October 2017Khanspersfixed interactions and updated layout
78439view10:26, 7 January 2015MaintBotadded missing graphIds
69159view18:19, 8 July 2013MaintBotUpdated to 2013 gpml schema
67644view11:43, 26 June 2013DdiglesOntology Term : 'sphingosine 1-phosphate signaling pathway' added !
41348view00:26, 2 March 2011MaintBotRemoved redundant pathway information and comments
33389view14:44, 30 November 2009MaintBotRemoved group label
32718view23:34, 2 September 2009MaintBotAdded groups and connected
20797view11:29, 14 November 2008MaintBot[[Pathway:Mus musculus:S1P Signaling]] moved to [[Pathway:WP57]]: Moved to stable identifier
8374view13:46, 7 January 2008MaintBot[[Pathway:Mouse:S1P Signaling]] moved to [[Pathway:Mus musculus:S1P Signaling]]: Renaming species
7805view16:19, 18 December 2007MaintBotfixed category names
7293view12:41, 4 November 2007MaintBotAdded categories to GPML
6492view22:19, 22 May 2007S.Donigergpml file for [[Mouse:S1P_Signaling]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Akt1GeneProduct11651 (Entrez Gene)
Akt2GeneProduct11652 (Entrez Gene)
Akt3GeneProduct23797 (Entrez Gene)
Asah2GeneProduct54447 (Entrez Gene)
Edg1GeneProduct13609 (Entrez Gene)
Edg3GeneProduct13610 (Entrez Gene)
Edg5GeneProduct14739 (Entrez Gene)
Edg8GeneProduct94226 (Entrez Gene)
Gnai1GeneProduct14677 (Entrez Gene)
Gnai2GeneProduct14678 (Entrez Gene)
Gnai3GeneProduct14679 (Entrez Gene)
Mapk12GeneProduct29857 (Entrez Gene)
Mapk1GeneProduct26413 (Entrez Gene)
Mapk3GeneProduct26417 (Entrez Gene)
Mapk6GeneProduct50772 (Entrez Gene)
Mapk7GeneProduct23939 (Entrez Gene)
Pik3c2gGeneProduct18705 (Entrez Gene)
Plcb3GeneProduct18797 (Entrez Gene)
Racgap1GeneProduct26934 (Entrez Gene)
Smpd2GeneProduct20598 (Entrez Gene)
Sphk1GeneProduct20698 (Entrez Gene)
Sphk2GeneProduct56632 (Entrez Gene)

Annotated Interactions

No annotated interactions

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