SARS-CoV-2 envelope lipid composition and human cell binding (Homo sapiens)

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1VirionEnvelopeMembranemostlyOuter leafletprocoagulantaminophospholipidPhospholipidsphosphatidyl-L-serinecholesterolBloodclothingsphingolipidssomesomeInner leafletphosphatidyl-ethanolamineAbundance:


Description

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Bibliography

  1. Saud Z, Tyrrell VJ, Zaragkoulias A, Protty MB, Statkute E, Rubina A, Bentley K, White DA, Rodrigues PDS, Murphy RC, Köfeler H, Griffiths WJ, Alvarez-Jarreta J, Brown RW, Newcombe RG, Heyman J, Pritchard M, Mcleod RW, Arya A, Lynch CA, Owens D, Jenkins PV, Buurma NJ, O'Donnell VB, Thomas DW, Stanton RJ; ''The SARS-CoV2 envelope differs from host cells, exposes procoagulant lipids, and is disrupted in vivo by oral rinses.''; J Lipid Res, 2022 PubMed Europe PMC Scholia
  2. Bohan D, Van Ert H, Ruggio N, Rogers KJ, Badreddine M, Aguilar Briseño JA, Elliff JM, Rojas Chavez RA, Gao B, Stokowy T, Christakou E, Kursula P, Micklem D, Gausdal G, Haim H, Minna J, Lorens JB, Maury W; ''Phosphatidylserine receptors enhance SARS-CoV-2 infection.''; PLoS Pathog, 2021 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
123355view14:18, 17 July 2022EgonwModified title
123354view14:03, 17 July 2022EgonwOntology Term : 'COVID-19' added !
123353view14:03, 17 July 2022EgonwOntology Term : 'disease pathway' added !
123352view14:01, 17 July 2022EgonwModified description
123351view13:19, 17 July 2022EgonwMade a pathway clickable
123247view06:32, 7 July 2022EgonwAdded details of the role of the envelope in cell uptake.
123219view14:09, 5 July 2022EgonwConfirmed the two are sPLs
123216view14:04, 5 July 2022EgonwExplain what the qualifiers mean
123213view14:03, 5 July 2022EgonwAdded details from the conclusions
123211view13:50, 5 July 2022EgonwAdded more knowledge from the abstract
123207view13:34, 5 July 2022EgonwAdded the main components as listed in the abstract
123206view13:23, 5 July 2022EgonwNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
Blood clothingPathway
PhospholipidsMetabolite16247 (ChEBI)
cholesterolMetabolite16113 (ChEBI)
phosphatidyl- ethanolamineMetabolite16038 (ChEBI)
phosphatidyl-L-serineMetabolite18303 (ChEBI)
procoagulant aminophospholipidMetabolite60971 (ChEBI)
sphingolipidsMetabolite26739 (ChEBI)

Annotated Interactions

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