EPA oxylipin metabolism (Homo sapiens)

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125-oxo-EPEPGI3LtC5EPA8(9)-EpETE20-HEPEPGE318-HpEPE5-HpEPERvE2TXA3PGH3CYP omega-hydroxylasedelta(12)-PGJ35(6)-EpETECOX-119-HEPEsEH11(12)-EpETE15-HpEPELxB512,18-DiHEPELOX12-HPEPELtB512,20-DiHEPE15-HEPE8,18-DiHEPE5,12-DiHEPE8,15-DiHEPE5,15-DiHEPERvE1PGD36-keto-PGF2α15-deoxy-delta(12,14)-PGJ3LtE5PGF3α11-HpEPE8,9-DiHETEASA8-HpEPE9-HpEPELtA511,18-DiHEPE9-HEPECOX-2LtD5RvE312-HEPE14,15-DiHETE11-HEPE8-HEPE5-HEPE17(18)-EpETE17,18-DiHETELxA518-HEPETXB3COX-214(15)-EpETE11,12-DiHETE5,6-DiHETECYP epoxygenase


Description

Eicosapentaenoic acid (EPA) oxylipin metabolism

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Quality Tags

Ontology Terms

 

Bibliography

  1. Gabbs M, Leng S, Devassy JG, Monirujjaman M, Aukema HM; ''Advances in Our Understanding of Oxylipins Derived from Dietary PUFAs.''; Adv Nutr, 2015 PubMed Europe PMC Scholia
  2. Wada M, DeLong CJ, Hong YH, Rieke CJ, Song I, Sidhu RS, Yuan C, Warnock M, Schmaier AH, Yokoyama C, Smyth EM, Wilson SJ, FitzGerald GA, Garavito RM, Sui de X, Regan JW, Smith WL; ''Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products.''; J Biol Chem, 2007 PubMed Europe PMC Scholia

History

CompareRevisionActionTimeUserComment
135484view22:48, 17 September 2024Lcayeradded d17-6k-PGF1a
123535view07:13, 2 August 2022EgonwTyped a metabolite
120229view20:14, 16 November 2021LcayerOntology Term : 'lipid metabolic pathway' added !
120215view15:24, 11 November 2021LcayerNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
11(12)-EpETEMetaboliteCHEBI:137267 (ChEBI)
11,12-DiHETEMetabolite16061121 (PubChem-compound)
11,18-DiHEPEMetabolite70698743 (PubChem-compound)
11-HEPEMetabolite16061130 (PubChem-compound)
11-HpEPEMetabolite
12,18-DiHEPEMetabolite70698744 (PubChem-compound)
12,20-DiHEPEMetabolite
12-HEPEMetabolite10041593 (PubChem-compound)
12-HPEPEMetaboliteQ27148022 (Wikidata)
14(15)-EpETEMetaboliteCHEBI:137269 (ChEBI)
14,15-DiHETEMetabolite16061119 (PubChem-compound)
15-HEPEMetaboliteHMDB10209 (HMDB)
15-HpEPEMetabolite16759352 (PubChem-compound)
15-deoxy-delta(12,14)-PGJ3MetaboliteQ60998653 (Wikidata)
17(18)-EpETEMetabolite16061089 (PubChem-compound)
17,18-DiHETEMetabolite16061120 (PubChem-compound)
18-HEPEMetabolite16061132 (PubChem-compound)
18-HpEPEMetaboliteCHEBI:138387 (ChEBI)
19-HEPEMetaboliteQ27146477 (Wikidata)
20-HEPEMetaboliteQ27146480 (Wikidata)
5(6)-EpETEMetabolite
5,12-DiHEPEMetaboliteCHEBI:88493 (ChEBI)
5,15-DiHEPEMetabolite
5,6-DiHETEMetabolite14429105 (PubChem-compound)
5-HEPEMetabolite6439678 (PubChem-compound)
5-HpEPEMetabolite5283184 (PubChem-compound)
5-oxo-EPEMetaboliteCHEBI:140244 (ChEBI)
6-keto-PGF2αMetabolite
8(9)-EpETEMetaboliteCHEBI:137193 (ChEBI)
8,15-DiHEPEMetabolite100956340 (PubChem-compound)
8,18-DiHEPEMetabolite70698745 (PubChem-compound)
8,9-DiHETEMetabolite16061118 (PubChem-compound)
8-HEPEMetabolite16061128 (PubChem-compound)
8-HpEPEMetabolite122391314 (PubChem-compound)
9-HEPEMetaboliteHMDB60053 (HMDB)
9-HpEPEMetabolite
ASAMetaboliteCHEBI:15365 (ChEBI)
COX-1GeneProduct5742 (Entrez Gene)
COX-2GeneProduct5743 (Entrez Gene)
CYP epoxygenaseGeneProduct
CYP omega-hydroxylaseGeneProductMultiple CYP enzymes with hydroxylase activity
EPAMetabolite446284 (PubChem-compound)
LOXGeneProduct
LtA5Metabolite
LtB5MetaboliteCHEBI:88493 (ChEBI)
LtC5MetaboliteHMDB12993 (HMDB)
LtD5MetaboliteHMDB12994 (HMDB)
LtE5Metabolite6439533 (PubChem-compound)
LxA5Metabolite53394742 (PubChem-compound)
LxB5Metabolite
PGD3MetaboliteCHEBI:34939 (ChEBI)
PGE3MetaboliteCHEBI:28031 (ChEBI)
PGF3αMetaboliteCHEBI:36075 (ChEBI)
PGH3MetaboliteCHEBI:134407 (ChEBI)
PGI3Metabolite5283049 (PubChem-compound)
RvE1Metabolite81559 (ChEBI)
RvE2Metabolite81560 (ChEBI)
RvE3Metabolite138477 (ChEBI)
TXA3Metabolite5283139 (PubChem-compound)
TXB3Metabolite5283140 (PubChem-compound)
delta(12)-PGJ3MetaboliteCHEBI:140274 (ChEBI)
sEHGeneProductENSG00000120915 (Ensembl)

Annotated Interactions

No annotated interactions

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