Male steroid hormones in cardiomyocyte energy metabolism (Homo sapiens)

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11, 31NucleusCardiomyocyte33, 4HSD3B13α-Androstane-diolAndrogen Receptor (AR)CYP11A1AndrostenediolHSD3B2HSD17B33β-HSDEpiandrosterone17α-HydroxypregnenoloneEtiocholanoloneAndrosteronePregnenoloneTestosterone3β-Eticholane-diolCholesterol3α-HSDSRD5A2/5β-reductaseHSD3B2HSD17B217β-HSDAndrostanedioneAromatase17β-HSDEstroneSulfotransferaseCYP17A1(C17,20-lyase)3α-HSD5α-Dihydro-testosteroneAromatase3β-Androstane-diolHSD17B3HSD3B13β-HSD17β-HSDGlucuronosyl-transferaseTestosteroneGlucuronideCYP17A1(17α-hydroxylase)Testosterone-sulfateSRD5A1Estradiol3α-Etiocholane-diolAKR1C3Dehydroepiandrosterone (DHEA)Epietio-cholanoloneAndrostenedioneSRD5A1/5α-reductaseProgesterone5β-Dihydro-testosteroneAKR1C317β-HSDHSD17B217β-HSDHSD17B3AKR1C3 SRD5A23β-HSD22, 311-31, 3142, 311111-31-31-32, 31, 321, 332, 32, 332, 32, 3


Description

The effect of androgens on cardiomyocytes

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Quality Tags

Ontology Terms

 

Bibliography

  1. Carbajal-García A, Reyes-García J, Montaño LM; ''Androgen Effects on the Adrenergic System of the Vascular, Airway, and Cardiac Myocytes and Their Relevance in Pathological Processes.''; Int J Endocrinol, 2020 PubMed Europe PMC Scholia
  2. Ishizaki F, Nishiyama T, Kawasaki T, Miyashiro Y, Hara N, Takizawa I, Naito M, Takahashi K; ''Androgen deprivation promotes intratumoral synthesis of dihydrotestosterone from androgen metabolites in prostate cancer.''; Sci Rep, 2013 PubMed Europe PMC Scholia
  3. Davey RA, Grossmann M; ''Androgen Receptor Structure, Function and Biology: From Bench to Bedside.''; Clin Biochem Rev, 2016 PubMed Europe PMC Scholia
  4. McEwan IJ, Brinkmann AO; ''Androgen Physiology: Receptor and Metabolic Disorders.''; , 2021 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
134471view00:47, 22 July 2024EweitzModified description
134470view00:46, 22 July 2024EweitzOntology Term : 'cardiac muscle cell' added !
125916view22:07, 17 March 2023EgonwMore fixed HMDB identifiers
125914view19:12, 17 March 2023EgonwNew HMDB format
125912view18:45, 17 March 2023EgonwUpdated the UniProt data sources
125903view13:59, 17 March 2023JmillanacostaAdded identifier
125868view17:27, 14 March 2023Bhavanakapalliidentifiers added
125623view20:02, 5 March 2023AlexanderPicoModified description
125617view11:38, 5 March 2023EgonwCorrect PubChem identifier (was for a silicon derivative)
125616view11:34, 5 March 2023EgonwRemoved duplicate reference info
125552view21:42, 26 February 2023AndraOntology Term : 'classic metabolic pathway' added !
125254view20:56, 30 January 2023Bhavanakapalliidentifiers
125253view20:53, 30 January 2023Bhavanakapalliidentifiers
125220view10:07, 30 January 2023BhavanakapalliReverted to version '10:05, 30 January 2023' by Bhavanakapalli
125219view10:06, 30 January 2023BhavanakapalliReverted to version '16:44, 29 January 2023' by Bhavanakapalli
125218view10:05, 30 January 2023Bhavanakapalli
125210view16:44, 29 January 2023Isissampermans
125209view16:42, 29 January 2023Isissampermans
125208view16:41, 29 January 2023Isissampermans
125207view16:39, 29 January 2023IsissampermansAddition of nucleus and cell structures
125205view15:53, 29 January 2023Isissampermans
125204view15:50, 29 January 2023IsissampermansNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
17α-HydroxypregnenoloneMetabolite
17β-HSDProtein
3α-Androstane-diolMetabolite
3α-Etiocholane-diolMetabolite
3α-HSDProtein
3β-Androstane-diolMetabolite
3β-Eticholane-diolMetabolite
3β-HSDProtein
3β-HSD2GeneProduct
5α-Dihydro-testosteroneMetabolite
5β-Dihydro-testosteroneMetabolite
AKR1C3GeneProduct
AKR1C3 ProteinAKR1C3 (Ensembl)
Androgen Receptor (AR)Metabolite
AndrostanedioneMetabolite
AndrostenediolMetabolite
Androstenedione Metabolite
AndrosteroneMetabolite
AromataseProtein
CYP11A1Protein
CYP17A1 (17α-hydroxylase)Protein
CYP17A1 (C17,20-lyase)Protein
CholesterolMetabolite
Dehydroepiandrosterone (DHEA)Metabolite
EpiandrosteroneMetabolite
Epietio- cholanoloneMetabolite
EstradiolMetabolite
EstroneMetabolite
EtiocholanoloneMetabolite
Glucuronosyl- transferaseProtein
HSD17B2Protein
HSD17B3GeneProduct
HSD3B1GeneProduct
HSD3B2GeneProduct
PregnenoloneMetabolite
ProgesteroneMetabolite
SRD5A1GeneProduct
SRD5A1/5α-reductaseGeneProduct
SRD5A2GeneProduct
SRD5A2/5β-reductaseGeneProduct
SulfotransferaseProtein
TestosteroneMetabolite
Testosterone GlucuronideMetabolite
Testosterone-sulfateMetabolite

Annotated Interactions

No annotated interactions

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