Phase I biotransformations, non-P450 (Bos taurus)
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1
Hydrolysis
OH
OH
OH
OH
amides
carboxylic acid esters
Phosphoric acid esters
thio esters
PON1
Phosphoric acid esters
PON3
CES5A
thio esters
LIPA
CES1
amides
PON2
CES2
ESD
carboxylic acid esters
Description
This pathway lists several phase 1 biotransformations and their related enzymes.
Comments
HomologyMapper
This pathway was inferred from Homo sapiens pathway
WP136(r95126)
with a 100.0% conversion rate.
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Quality Tags
Ontology Terms
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Bibliography
Klaassen, C.D., Watkins III, J.B.; ''Casarett & Doull's Essentials of Toxicology''; , 2003
History
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Revision
Action
Time
User
Comment
128191
view
00:34, 29 January 2024
Eweitz
Modified title
125260
view
12:09, 31 January 2023
Larsgw
Add ISBN to publication
107051
view
14:13, 17 September 2019
MaintBot
ChEBI identifier normalization
95737
view
13:07, 19 January 2018
Mkutmon
updated homology conversion
95736
view
13:01, 19 January 2018
Mkutmon
removed outdated last updated statement
80914
view
15:31, 30 June 2015
Mkutmon
homology conversion
73511
view
23:18, 29 January 2014
Khanspers
Modified title
63452
view
17:14, 10 May 2013
MaintBot
Updated to 2013 gpml schema
58826
view
23:19, 20 February 2013
MaintBot
Updated Ensembl and UniProt data source
40586
view
19:33, 1 March 2011
MaintBot
Removed redundant pathway information and comments
33824
view
00:25, 9 December 2009
MaintBot
Automatic update of empty xrefs
31662
view
11:39, 14 August 2009
MaintBot
Fixed group labels
30590
view
22:12, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
CES1
GeneProduct
ENSBTAG00000011021 (Ensembl)
Homology Mapping from Homo sapiens to Bos taurus: Original ID = En:ENSG00000198848
CES2
GeneProduct
ENSBTAG00000005093 (Ensembl)
Homology Mapping from Homo sapiens to Bos taurus: Original ID = En:ENSG00000172831
CES5A
GeneProduct
ENSBTAG00000011164 (Ensembl)
Homology Mapping from Homo sapiens to Bos taurus: Original ID = En:ENSG00000159398
ESD
GeneProduct
ENSBTAG00000003415 (Ensembl)
Homology Mapping from Homo sapiens to Bos taurus: Original ID = En:ENSG00000139684
LIPA
GeneProduct
ENSBTAG00000003636 (Ensembl)
Homology Mapping from Homo sapiens to Bos taurus: Original ID = En:ENSG00000107798
PON1
GeneProduct
ENSBTAG00000015654 (Ensembl)
Homology Mapping from Homo sapiens to Bos taurus: Original ID = En:ENSG00000005421
PON2
GeneProduct
ENSBTAG00000008361 (Ensembl)
Homology Mapping from Homo sapiens to Bos taurus: Original ID = En:ENSG00000105854
PON3
GeneProduct
ENSBTAG00000034645 (Ensembl)
Homology Mapping from Homo sapiens to Bos taurus: Original ID = En:ENSG00000105852
Phosphoric acid esters
Metabolite
CHEBI:37734 (ChEBI)
amides
Metabolite
CHEBI:32988 (ChEBI)
carboxylic acid esters
Metabolite
CHEBI:33308 (ChEBI)
thio esters
Metabolite
CHEBI:51277 (ChEBI)
Annotated Interactions
No annotated interactions
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View approved pathways at the new wikipathways.org.Quality Tags
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Annotated Interactions
No annotated interactions