Iron homeostasis (Mus musculus)
From WikiPathways
Description
Iron is nessisary for all mammalian cells but is also toxic in excess. This pathway shows the regulation of iron between a cell and the blood stream.
Quality Tags
Ontology Terms
Pathway Ontology : methylmalonic aciduria, cobalamin-related pathway mitochondria dynamics pathway cobalamin metabolic pathway
Disease : methylmalonic acidemia methylmalonic aciduria and homocystinuria type cblF methylmalonic aciduria and homocystinuria type cblC vitamin B12 deficiency methylmalonic acidemia cb1A type methylmalonic aciduria and homocystinuria type cblD methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency methylmalonic acidemia cb1B type
Cell Type : metabolising cell eukaryotic cell
Bibliography
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History
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External references
DataNodes
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Name ![]() | Type ![]() | Database reference ![]() | Comment ![]() |
---|---|---|---|
BMP1/2/4/9 | GeneProduct | ||
BMPR-1 | GeneProduct | ||
Ferroportin | GeneProduct | ENSMUSG00000025993 (Ensembl) ![]() | |
Fth1 | GeneProduct | 14319 (Entrez Gene) ![]() | |
Ftl1 | GeneProduct | ENSMUSG00000050708 (Ensembl) ![]() | |
Hfe | GeneProduct | ENSMUSG00000006611 (Ensembl) ![]() | |
IL-1 | GeneProduct | ENSMUSG00000027399 (Ensembl) ![]() | |
IL-6 | GeneProduct | ENSMUSG00000025746 (Ensembl) ![]() | |
IL1R | GeneProduct | ||
IL6R | GeneProduct | ENSMUSG00000027947 (Ensembl) ![]() | |
Ireb2 | GeneProduct | ENSMUSG00000032293 (Ensembl) ![]() | |
Iron | Metabolite | HMDB0000692 (HMDB) ![]() | |
JAK1/2 | GeneProduct | ||
SMAD-1/5/8 | GeneProduct | ||
STAT3 | GeneProduct | ||
Tnf | GeneProduct | ENSMUSG00000024401 (Ensembl) ![]() | |
Transferrin | GeneProduct | ENSMUSG00000032554 (Ensembl) ![]() | |
Trfr1 | GeneProduct | ||
Trfr2 | GeneProduct | ENSMUSG00000029716 (Ensembl) ![]() | |
cMyc | GeneProduct | ||
hemojuvelin | GeneProduct | ENSMUSG00000038403 (Ensembl) ![]() | |
hepcidin-2 | GeneProduct | ENSMUSG00000056978 (Ensembl) ![]() | |
hepcidin | GeneProduct | ENSMUSG00000050440 (Ensembl) ![]() |
Annotated Interactions
No annotated interactions