Vitamin A1 and A5/X pathways (Homo sapiens)

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11-31Vitamin A5/XsdietRXRATBCvitamin A5/X-activity9CDHROL-ES39CDHROL9CBC9CDHBC9CDHRA39CDHRA-ES111RARvitamin A1-activityATRAATRALATROLATROL-ESVitamin A1


Description

Vitamin A5/X pathway

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Quality Tags

Ontology Terms

 

Bibliography

  1. Krężel W, Rivas A, Szklenar M, Ciancia M, Alvarez R, de Lera AR, Rühl R; ''Vitamin A5/X, a New Food to Lipid Hormone Concept for a Nutritional Ligand to Control RXR-Mediated Signaling.''; Nutrients, 2021 PubMed Europe PMC Scholia
  2. Rühl R, Krzyżosiak A, Niewiadomska-Cimicka A, Rochel N, Szeles L, Vaz B, Wietrzych-Schindler M, Álvarez S, Szklenar M, Nagy L, de Lera AR, Krężel W; ''9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice.''; PLoS Genet, 2015 PubMed Europe PMC Scholia
  3. de Lera, A.R., Krezel, W., Ruehl, R.; ''An Endogenous Mammalian Retinoid X Receptor Ligand, At Last!''; ChemMedChem, 2016 DOI Scholia

History

View all...
CompareRevisionActionTimeUserComment
135005view08:32, 31 July 2024EgonwAdded a missing identifier
134437view23:39, 21 July 2024EweitzMake pathway label human-friendly
134436view23:34, 21 July 2024EweitzEconomize layout, standardize case
127034view06:23, 25 July 2023EgonwModified description
127032view17:15, 24 July 2023EgonwAdded all receptors (see WP716) with identifiers (NCBI Gene)
127031view17:08, 24 July 2023EgonwMore and fixed identifiers
127030view16:20, 24 July 2023EgonwFirst few metabolite identifiers
127003view13:53, 17 July 2023Ash iyerOntology Term : 'metabolic pathway of cofactors, vitamins, nutrients' added !
127002view13:53, 17 July 2023Ash iyerOntology Term : 'retinol metabolic pathway' added !
127001view13:52, 17 July 2023Ash iyerOntology Term : 'vitamin A and metabolites signaling pathway' added !
127000view13:51, 17 July 2023Ash iyerOntology Term : 'PW:0000001' removed !
126999view13:51, 17 July 2023Ash iyerOntology Term : 'Pathway Ontology' added !
126995view18:54, 12 July 2023EgonwFirst identifier and link to the main Vit A pathway
126994view15:13, 12 July 2023EgonwSome prettifying
126991view14:57, 12 July 2023EgonwOne reference is not in PubMed, using the DOI
126990view14:53, 12 July 2023EgonwMore literature references
126988view14:34, 12 July 2023EgonwAdded the first literature reference to various individual steps
126985view14:22, 12 July 2023EgonwNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
9CBCMetabolite
9CDHBCMetabolite
9CDHRAMetabolite
  • vitamin A5/X acid
  • Both R and S forms bind, but R better. The R stereoisomer is patented
9CDHRA-ESMetabolite
9CDHROLMetabolite
9CDHROL-ESMetabolite
ATBCMetaboliteprovitamin A1
ATRAMetabolitevitamin A1 acid
ATRALMetabolitevitamin A1 aldehyde
ATROLMetabolitevitamin A1
ATROL-ESMetabolitevitamin A1
RARProtein
RXRProtein
diet
vitamin A1-activityPathway
vitamin A5/X-activityPathway

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP5397"
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