Tissue fate map (Homo sapiens)

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MesodermLungsMesendodermSmall intestineGloubus Pallidum InternalHemangioblast tissueMesoderm progenitorKidney cortexVaginaPharynxStomach fundusSubthalamic NucleusSerotonergic ProgenitorStroma of gonadsPrimitive gutSomatic mesodermEndocardiumIntermediate mesodermLymph nodesGlobus PallidusVisceraPutamenCaudateAccumbensAmygdalaFetal kidneyAxial skeletonUrethraFetal thyroidThalamus Subthalamic NucleusMyeloid progenitorGranulocytesTemporal LobePharyngeal pouchesHematopoietic progenitorSebacious GlandsCerebellumSubstantia NigraAdipocyte progenitorFetal Spinal CordT cellsSpinal CordNailsMedullaJoint tissue synoviumDuodenumThalamusHeartCoronary arteryConnective tissue layers of skinOligodendrocyte ProgenitorPeritoneumCrainial Motor NervesVena cavaVentral mesodermOral MucosaEctoderm progenitorFetal pancreasLiverAppendecular skeletonBronchiScleroteomesVentral Tegmental AreaFetal leg muscleJejunumEndothelium of blood vesselsLymphoid progenitorMammary GlandsTongueMedulla of AdrenalOccipital LobeTrophoectodermEndometriumDigestive tubeCranial Sensory Ganglia and NervesMesonephric ductsHead musclesB CellsForebrainFetal LiverCD4+Fetal adrenal cortexSubcorticalGlutamatergic ProgenitorVulvaBreastMesenchymeGloubus Pallidum ExternalGlial CellsParietal LobeAortaFetal BrainHairAnal CanalSubstantia Nigra Pars CompactaPrefrontal CortexUterusTongue main corpusKeratinocytesDorsal-paraxial mesodermPluripotent stem cellsCephalic connective tissueMonocytesBlood corpusclesLarge intestineThalamus Lateral NucleiDeltoid muscleColonPancreasTestesKidney medullaHead mesenchymeMicrogliaTonsillar recessesSynovial membraneAppendage musclesSaphenous veinMyotubeEsophagusEpicardiumAuditory VescicleProstate glandPenisNeural Stem CellsSchwann Cell ProgenitorOuter Epithelium of BodySpinal Dorsal Root GangliaGABAergic ProgenitorNeural TubePars Neuralis of HypophysisCervixMullerian ductsTeeth EnamelSubcutaneous adiposeSensory Sinal Nerve RootsFrontal CortexOmental adiposeDentin of TeethLeg muscleHindbrainSubstantia Nigra ReticulataVisceral pleuraAdipose tissueProstateArm musclePlacentaTrigeminal GangliaCD8+Sweat GlandsAllantoisAtriumConnective tissueNippleCerebellar VermisBone marrowHypothalamusOsteoblastsMyocardiumCortexParathyroidsTongue Superior With PapillaeErythroblast progenitorVestibular Nuclei SuperiorCerebellar HemisphereEpimyocardiumCD34+Outer layers of eyeKidneyEpididymisCytotrophoblastAstrocyte ProgenitorNasal-Olfactory EpitheliumPharyngeal mucosaStomodaeal EpitheliumVentricleNeural Crest Mesenchymal Stem CellsTracheaCorpus CallosumThyroidBlood vesselsPathwayVisceral peritoneumHemangioblastic stem cellsDorsal Root GangliaStomachBlastocystDopaminergic ProgenitorPleuraEye LensMyometriumPericardiumRetrocervical infiltrateNK cellsStomach cardiacVas deferensStomach pyloricEndothelial cellsNeural ProgenitorFetal arm muscleMiddle earFetal lungsHypophysis Anteriror LobeFetal heartSkinFallopian tubeZygoteFrontal LobeSympathetic GangliaPituitary GlandOvariesCholinergic ProgenitorRetinaLateral mesodermMorulaBrainSplanchnic mesodermCerebral CortexThymusEarly endoderm progenitorUrinary bladderSpleenOral EpitheliumOviductsMyoblastFetal thymusHippocampusMesentariesSkull and branchial cartilagesMyotomesSyncytiotrophoblastMidbrainSmooth muscle cellsChondrocytesTonsilPonsDermatomesDorsolateral Prefrontal NeocortexMedial Prefrontal NeocortexOrbital Prefrontal NeocortexBloodSchwann CellsDopaminergicOligodendrocytesSerotonergicAstrocytesGABAergicGlutamatergicCholinergicErythrocytesVentrolateral Prefrontal NeocortexStriatum Putamen and Caudate NucleusParietal Association NeocortexOccipital Visual NeocortexTemporal Auditory NeocortexTemporal Association CortexMediodorsal ThalamusInduced pluripotent stem cellsFetal kidney renal cortexFetal kidney renal pelvisAdipocytesAorta smooth muscle cellsAdrenal cortexEndodermCardiac progenitorCardiomyocytesSkeletal muscleFetal skeletal muscleNeural CrestNeural Crest Stem CellsMelanocyteMotor Somatosensory NeocortexBone marrow stem cellsBone marrow mesenchymal stem cellsChorionEpithelial cellsEmbryonic fibroblastsMiddle first trimesterLate first trimesterSecond trimesterLeft atriumRight atriumLeft ventricleRight ventricleIslet cellsThymocytesMuscleEarly first trimesterBone marrow hematopoietic progenitorsPerivascular adiposeWhite adiposeBrown adiposeEpididymal adiposeCD19+CD71+Liver hematopoietic stem cellsVisual CortexThymocytePartially reprogrammed iPS cellsFibroblastsCardiac fibroblast progenitorCardiac fibroblastsHepatocytesPrimordial germ cellsSpermatogonial stem cellsOocytesMacrophagesTrophoectoderm stem cellsCD14+MegakaryocyteOptic NervePhotoreceptor CellsRetina Inner Nuclear CellsRetina Inner Plexiform CellsRetina Ganglion CellsDermal Stem CellDermal ProgenitorColon CecumSalivary GlandMesenchymal stem cellsEmbryoEndoderm progenitorEctodermEndodermFetusAdrenal glandBoneNodose NucleusFetal small intestineFetal large intestineHepatoblasts


Description

Proposed lineage fate map focusing on (1) adult tissues, (2) fetal tissues, (3) terminally differentiated cells, (5) stem cells and (4) progenitor cells. This pathway is currently in progress but will ultimately be a hub to tissue and cell type specific pathways (nodes converted to pathway nodes).

How to Use

This network is most useful when viewed in Cytoscape with corresponding cell/tissue association data. To use, simply save the GPML and open in Cytoscape (File > Import > Network (Multiple File Types)...) and change the visual style of the pathway to one of the default options under VizMapper > Current Visual Style or load this specific VisualStyle: http://altanalyze.org/TissueFateMap-VizMapperProperty.props. To visualize tissue/cell association data, load an attribute file with corresponding tissue/cell names (e.g., from AltAnalyze's TissueMapper software) using File > Import > Node Attributes (mapping the tissue column to CanonicalName) and set your coloring parameters from VizMapper > Node Color.

Try the New WikiPathways

View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
127710view20:44, 24 November 2023EweitzStandardize case, fix typos
116656view11:46, 9 May 2021EweitzModified title
87775view11:06, 25 July 2016MirellaKalafatiOntology Term : 'regulatory pathway' added !
62399view02:51, 28 April 2013MaintBotCleaned up remaining xref errors
62398view02:48, 28 April 2013MaintBotRemoved datasource from empty xrefs
62397view02:47, 28 April 2013MaintBotUpdating GPML version
57682view20:50, 31 January 2013KhanspersModified categories
54699view12:45, 7 December 2012Andra
54698view12:37, 7 December 2012AndraRDFTidy
47899view19:14, 17 April 2012NsalomonisSpecify description
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47893view18:44, 17 April 2012NsalomonisPeriodical save, work in progress
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47866view06:49, 16 April 2012NsalomonisPeriodical save, work in progress
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47857view17:41, 15 April 2012NsalomonisPeriodical save, work in progress
45929view00:10, 29 November 2011NsalomonisModified description
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45917view21:21, 27 November 2011NsalomonisSpecify description
45845view16:03, 17 November 2011NsalomonisSpecify description
45776view04:29, 9 November 2011NsalomonisSpecify description
45767view01:33, 7 November 2011NsalomonisSpecify description
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45728view23:33, 2 November 2011NsalomonisSpecify description
45727view23:28, 2 November 2011NsalomonisSpecify description
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External references

DataNodes

View all...
NameTypeDatabase referenceComment
Accumbens
Adipocyte progenitor
Adipocytes
Adipose tissue
Adrenal cortex
Adrenal gland
Allantois
Amygdala
Anal Canal
Aorta
Aorta smooth muscle cells
Appendage muscles
Appendecular skeleton
Arm muscle
Astrocyte Progenitor
Astrocytes
Atrium
Auditory Vescicle
Axial skeleton
B Cells
Blastocyst
Blood
Blood corpuscles
Blood vessels
Bone
Bone marrow
Bone marrow hematopoietic progenitors
Bone marrow mesenchymal stem cells
Bone marrow stem cells
Brain
Breast
Bronchi
Brown adipose
CD14+
CD19+
CD34+
CD4+
CD71+
CD8+
Cardiac fibroblast progenitor
Cardiac fibroblasts
Cardiac progenitor
Cardiomyocytes
Caudate
Cephalic connective tissue
Cerebellar Hemisphere
Cerebellar Vermis
Cerebellum
Cerebral Cortex
Cervix
Cholinergic
Cholinergic Progenitor
Chondrocytes
Chorion
Colon
Colon Cecum
Connective tissue
Connective tissue layers of skin
Coronary artery
Corpus Callosum
Cortex
Crainial Motor Nerves
Cranial Sensory Ganglia and Nerves
Cytotrophoblast
Deltoid muscle
Dentin of Teeth
Dermal Progenitor
Dermal Stem Cell
Dermatomes
Digestive tube
Dopaminergic
Dopaminergic Progenitor
Dorsal Root Ganglia
Dorsal-paraxial mesoderm
Dorsolateral Prefrontal Neocortex
Duodenum
Early endoderm progenitor
Early first trimester
Ectoderm progenitor
Embryo
Embryonic fibroblasts
Endocardium
Endoderm
Endoderm progenitor
Endometrium
Endothelial cells
Endothelium of blood vessels
Epicardium
Epididymal adipose
Epididymis
Epimyocardium
Epithelial cells
Erythroblast progenitor
Erythrocytes
Esophagus
Eye Lens
Fallopian tube
Fetal Brain
Fetal Liver
Fetal Spinal Cord
Fetal adrenal cortex
Fetal arm muscle
Fetal heart
Fetal kidney
Fetal kidney renal cortex
Fetal kidney renal pelvis
Fetal large intestine
Fetal leg muscle
Fetal lungs
Fetal pancreas
Fetal skeletal muscle
Fetal small intestine
Fetal thymus
Fetal thyroid
Fetus
Fibroblasts
Forebrain
Frontal Cortex
Frontal Lobe
GABAergic
GABAergic Progenitor
Glial Cells
Globus Pallidus
Gloubus Pallidum External
Gloubus Pallidum Internal
Glutamatergic
Glutamatergic Progenitor
Granulocytes
Hair
Head mesenchyme
Head muscles
Heart
Hemangioblast tissue
Hemangioblastic stem cells
Hematopoietic progenitor
Hepatoblasts
Hepatocytes
Hindbrain
Hippocampus
Hypophysis Anteriror Lobe
Hypothalamus
Induced pluripotent stem cells
Intermediate mesoderm
Islet cells
Jejunum
Joint tissue synovium
Keratinocytes
Kidney
Kidney cortex
Kidney medulla
Large intestine
Late first trimester
Lateral mesoderm
Left atrium
Left ventricle
Leg muscle
Liver
Liver hematopoietic stem cells
Lungs
Lymph nodes
Lymphoid progenitor
Macrophages
Mammary Glands
Medial Prefrontal Neocortex
Mediodorsal Thalamus
Medulla
Medulla of Adrenal
Megakaryocyte
Melanocyte
Mesenchymal stem cells
Mesenchyme
Mesendoderm
Mesentaries
Mesoderm progenitor
Mesonephric ducts
Microglia
Midbrain
Middle ear
Middle first trimester
Monocytes
Morula
Motor Somatosensory Neocortex
Mullerian ducts
Muscle
Myeloid progenitor
Myoblast
Myocardium
Myometrium
Myotomes
Myotube
NK cells
Nails
Nasal-Olfactory Epithelium
Neural Crest
Neural Crest Mesenchymal Stem Cells
Neural Crest Stem Cells
Neural Progenitor
Neural Stem Cells
Neural Tube
Nipple
Nodose Nucleus
Occipital Lobe
Occipital Visual Neocortex
Oligodendrocyte Progenitor
Oligodendrocytes
Omental adipose
Oocytes
Optic Nerve
Oral Epithelium
Oral Mucosa
Orbital Prefrontal Neocortex
Osteoblasts
Outer Epithelium of Body
Outer layers of eye
Ovaries
Oviducts
Pancreas
Parathyroids
Parietal Association Neocortex
Parietal Lobe
Pars Neuralis of Hypophysis
Partially reprogrammed iPS cells
Pathway
Penis
Pericardium
Peritoneum
Perivascular adipose
Pharyngeal mucosa
Pharyngeal pouches
Pharynx
Photoreceptor Cells
Pituitary Gland
Placenta
Pleura
Pluripotent stem cells
Pons
Prefrontal Cortex
Primitive gut
Primordial germ cells
Prostate
Prostate gland
Putamen
Retina
Retina Ganglion Cells
Retina Inner Nuclear Cells
Retina Inner Plexiform Cells
Retrocervical infiltrate
Right atrium
Right ventricle
Salivary Gland
Saphenous vein
Schwann Cell Progenitor
Schwann Cells
Scleroteomes
Sebacious Glands
Second trimester
Sensory Sinal Nerve Roots
Serotonergic
Serotonergic Progenitor
Skeletal muscle
Skin
Skull and branchial cartilages
Small intestine
Smooth muscle cells
Somatic mesoderm
Spermatogonial stem cells
Spinal Cord
Spinal Dorsal Root Ganglia
Splanchnic mesoderm
Spleen
Stomach
Stomach cardiac
Stomach fundus
Stomach pyloric
Stomodaeal Epithelium
Striatum Putamen and Caudate Nucleus
Stroma of gonads
Subcortical
Subcutaneous adipose
Substantia Nigra
Substantia Nigra Pars Compacta
Substantia Nigra Reticulata
Subthalamic Nucleus
Sweat Glands
Sympathetic Ganglia
Syncytiotrophoblast
Synovial membrane
T cells
Teeth Enamel
Temporal Association Cortex
Temporal Auditory Neocortex
Temporal Lobe
Testes
Thalamus
Thalamus Lateral Nuclei
Thalamus Subthalamic Nucleus
Thymocyte
Thymocytes
Thymus
Thyroid
Tongue
Tongue Superior With Papillae
Tongue main corpus
Tonsil
Tonsillar recesses
Trachea
Trigeminal Ganglia
Trophoectoderm
Trophoectoderm stem cells
Urethra
Urinary bladder
Uterus
Vagina
Vas deferens
Vena cava
Ventral Tegmental Area
Ventral mesoderm
Ventricle
Ventrolateral Prefrontal Neocortex
Vestibular Nuclei Superior
Viscera
Visceral peritoneum
Visceral pleura
Visual Cortex
Vulva
White adipose
Zygote

Annotated Interactions

No annotated interactions

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