Cancer pathways (Homo sapiens)

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MitochondriaMicrotubulePU.1 target genesWntLigands?ECMWntDNA damageFrizzledTelomeric DNA repeatsSustainedangiogenesisCytokine receptorOxidative or electrophilic stressGSTsCarcinogensRARatarget genesCTNNB1CSF3RCASP9APAF1BCL2L1DehydroepiandrosteronePRKACACTNNB1BCL2L11NKX3-1PDGFBEDN1IP3PLCG1PMAIP1RETSHHPPARDIP3AGTCRKPTCH1MTORCDKN1BEstradiolTGFBR2CDKN1BE2F1BAK1MYCCTNNA1EGFRNCOA3JAG1DDB2RASSF1RALAVEGFDDCCRetinoic AcidRBX1ApoptosisCSF2RATERTCREBBPFOSFocal adhesionBBC3FLT4STAT1APPL1fumarateCSF1RCCND1HRASSOS1PTENMSH2LEF1HMOX1RB1CALML1BADTERCSuperoxideMSH6DVL1CASP8EDNRAMDM2GNA11APC2HHIPBMP2ITGA6MECOMWnt signalingpathwaySKP1RASSF5GNAI1GADD45GCTBP1TGFB1ADCY1IGF1AcroleinRARBKNG1RALBP1GSK3BRASGRP1FASLGNitric oxideSPI1TXNRD1VEGF signalingpathwayARHGEF12FLT3EstradiolCDKN2BCDH1ETS1CDK2PDGFAFADDp53 signalingpathwayRXRAHIF-1 signalingpathwayPLCB1CYCSMITFTGF-beta signalingpathwayARAFBAK1RPS6KA5CDKN2ATRAF1RASSF1PGE2FGF1CKS1BSTAT3DLL3CASP3STAT5APOLKBCL2L1RHOACXCR4ARNTHydrogen peroxideBADEGLN2MAPK8VHLTGFAcAMP signalingpathwayRUNX1HSP90AA1EGFRPS6KB1PPARGNotch signaling pathwayLRP5PDGFRAARPAPMLPRKCAJUPSMAD4ELK1AXIN1CASP3NFE2L2ROCK1IGF1RRALGDSPI3K-Aktsignaling pathwayHGFPTCH1CCNE1MYCSMAD2KITLGPIM2PGFTGFB1Ca2+RUNX1Hydroxyl radicalFGFR1ITGB1Jak-STAT signaling pathwayBRCA2CXCL8CCND1CTNNB1CholesterolLPAR6GSTP1SKP2MMP1PLD1PIP3CASP3STAT2BIDMLH1HEY1MAP2K1Calcium signalingpathwayELOCCCNA2PPAR signalingpathwayCASP9GNB5CCND1MSH3NOTCH1Estrogen signalingpathwayZBTB17Adherens junctionMAXPIK3CAPTGS2NFKBIAJAK1EPAS1HDAC1DAGDAPK1BAXESR1FOXO1CEBPACDK4NOS2cAMPELOBF2Hydroperoxyl radicalFHBCL2MYCCDK4BIRC5NQO1CDKN2AGNASJUNCDKN1AFLT3LGERBB2CDKN1ARARAKLK3RHOAABL1METGLI1FASGRB2TP53Cell cycleTGFBR2TGFAIL6MDM2TFGSLC2A1TestosteroneBCL2RAD51mTOR signalingpathwayFRAT1GNA13MAPK signalingpathwaySUFUPTGER1BAXHES1Hedgehog signaling pathwayMYCBIRC2ProgesteroneKIF7KITCHUKTP53KEAP1TGFBR1CAMK2AMAPK1RAC1NFKB1DNASMOCUL2ALKPTK2SPI1CXCL12PJAG2DLL4DLL1GLI2GLI3DihydrotestosteroneFlutamideAndrostenedioneCortisolCortisoneARHSP90AB1HSP90B1ARNOTCH2NOTCH3NOTCH4BMP4GLI1PTCH2HES5HEY2HEYLEGLN1EGLN3MalateHIF1AARNT2EP300VEGFAVEGFBVEGFCTGFB2TGFB34-HNETXNRD2TXNRD3CASP7Evaiding apoptosisMitochondriaTGFB2TGFB3SMAD3Genomic damageInsesitivity toanti-growth signalsResistance tochemotherapyImmortalityHDAC2CTBP2DNAGenomic instabilityGADD45BGADD45ACDK6CCND2CCND3E2F2E2F3ProliferationCCNE2RBX1CUL1CKS1BBlock ofdifferentiationE2F1E2F2E2F3CSF1RCSF1RC/EBPa target genesCEBPAAML1 target genesRARAZBTB16RUNX1RUNX1T1CCNA1CCND1TCF7TCF7L2TCF7L1SP1ESR2NCOA1ESR1ESR2EstradiolEstradiolRXRBRXRGRXRARXRBRXRGPPARGPAX8CCND1VEGFDVEGFAVEGFBVEGFCMMP2MMP3FOSMYCJUNMAPK3DAPK2DAPK3MAP2K2BRAFRAF1NRASKRASSOS2ERBB2PDGFRBFGFR2FGFR3FGFR4Cytokine IGF2PDGFBRALBPLD2RAC2RAC3MAPK9MAPK10RAC1RAC2RAC3CCDC42PLCG2EML4PRKCBPRKCGCCDC6NCOA4NTRK1TPM3TPRTissue invasion and metastasisCTNNA3CTNNA2AXIN2APCFRAT2DVL2DVL3MYCCCND1LEF1TCF7TCF7L2TCF7L1PGFVEGFDVEGFAVEGFBVEGFCLRP6PTGER2PTGER3PTGER4AGTR1LPAR1F2RLPAR2LPAR3LPAR4LPAR5F2RL3GNA12ARHGEF11ARHGEF1PLEKHG5ROCK2GNAI2GNAI3ADCY2ADCY3ADCY4ADCY5ADCY6ADCY7ADCY8ADCY9PRKACBPRKACGGNB1GNB2GNB3GNG3GNG4GNG5GNG7GNG10GNG11GNGT1BCL2L1PIM1BIRC3BIRC7XIAPTRAF2TRAF3TRAF4TRAF5TRAF6GNGT2GNG13GNG2GNG12GNG8GNB4ITGA2ITGA2BITGA3ITGAVEDNRBF2AGTBDKRB1BDKRB2GNAQPLCB2PLCB3PLCB4PRKCAPRKCBPRKCGCa2+DAGJAK2JAK3RASGRP2RASGRP3RASGRP4ALKEML4MST1STAT5BSTAT4STAT6BCRCBLCRKLPIK3CBPIK3CDPIK3R1PIK3R2PIK3R3AKT1AKT2AKT3IKBKBIKBKGNFKB2RELACASP9BCL2L1RPS6KB2CALML2CALML3CALML4CALML5CALML6CAMK2BCAMK2DCAMK2G


Description

draft pathway describing pathways in cancer

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View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

  1. ''Pathways in cancer''; https://www.kegg.jp/dbget-bin/www_bget?pathway+hsa05200,

History

View all...
CompareRevisionActionTimeUserComment
135326view19:19, 21 August 2024Khanspersupdated kegg reference
135315view21:04, 19 August 2024Khanspersupdate KEGG ref
129459view01:04, 23 April 2024EweitzModified title
129136view16:45, 12 March 2024Khanspersminor tweak to test
128705view22:04, 20 February 2024EgonwMade a few pathways clickable
128257view00:14, 30 January 2024KhanspersModified description
128256view00:11, 30 January 2024Khanspersupdated lit ref
128254view00:08, 30 January 2024KhanspersOntology Term : 'cancer' added !
128253view00:08, 30 January 2024KhanspersOntology Term : 'altered signaling pathway' added !
128252view00:06, 30 January 2024Khanspersadded cell shape, legend, phospho sites
127898view00:17, 10 January 2024Khanspersnode sizing and layout
127897view00:08, 10 January 2024Khanspersadded cytokines and cytokine receptors
127896view22:57, 9 January 2024Khansperslayout
127895view22:51, 9 January 2024Khanspersadded wnts
127872view22:50, 3 January 2024Khansperslayout
127871view19:59, 3 January 2024Khansperscomplexes and interactions
127866view23:51, 2 January 2024Khanspersinteractions
127865view23:38, 2 January 2024Khanspersupdated interactions etc
127864view22:58, 2 January 2024Khansperslayout and interactions
127863view22:51, 2 January 2024Khanspersadded gst
127861view22:41, 2 January 2024Khanspersadded ecm
127859view22:33, 2 January 2024Khanspersadded wnt, fzd
127827view21:26, 21 December 2023KhanspersOntology Term : 'cancer pathway' added !
127826view21:25, 21 December 2023KhanspersModified title
127825view21:24, 21 December 2023KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
4-HNEMetaboliteC21642 (KEGG Compound)
ABL1GeneProductABL1 (HGNC)
ADCY1GeneProductADCY1 (HGNC)
ADCY2GeneProductADCY2 (HGNC)
ADCY3GeneProductADCY3 (HGNC)
ADCY4GeneProductADCY4 (HGNC)
ADCY5GeneProductADCY5 (HGNC)
ADCY6GeneProductADCY6 (HGNC)
ADCY7GeneProductADCY7 (HGNC)
ADCY8GeneProductADCY8 (HGNC)
ADCY9GeneProductADCY9 (HGNC)
AGTGeneProductAGT (HGNC)
AGTR1GeneProductAGTR1 (HGNC)
AKT1GeneProductAKT1 (HGNC)
AKT2GeneProductAKT2 (HGNC)
AKT3GeneProductAKT3 (HGNC)
ALKGeneProductALK (HGNC)
APAF1GeneProductAPAF1 (HGNC)
APC2GeneProductAPC2 (HGNC)
APCGeneProductAPC (HGNC)
APPL1GeneProductAPPL1 (HGNC)
ARAFGeneProductARAF (HGNC)
ARGeneProductAR (HGNC)
ARHGEF11GeneProductARHGEF11 (HGNC)
ARHGEF12GeneProductARHGEF12 (HGNC)
ARHGEF1GeneProductARHGEF1 (HGNC)
ARNT2GeneProductARNT2 (HGNC)
ARNTGeneProductARNT (HGNC)
AXIN1GeneProductAXIN1 (HGNC)
AXIN2GeneProductAXIN2 (HGNC)
AcroleinMetaboliteC01471 (KEGG Compound)
Adherens junctionPathway
AndrostenedioneMetaboliteHMDB00053 (HMDB)
ApoptosisPathwayWP254 (WikiPathways)
BADGeneProductBAD (HGNC)
BAK1GeneProductBAK1 (HGNC)
BAXGeneProductBAX (HGNC)
BBC3GeneProductBBC3 (HGNC)
BCL2GeneProductBCL2 (HGNC)
BCL2L11GeneProductBCL2L11 (HGNC)
BCL2L1GeneProductBCL2L1 (HGNC)
BCRGeneProductBCR (HGNC)
BDKRB1GeneProductBDKRB1 (HGNC)
BDKRB2GeneProductBDKRB2 (HGNC)
BIDGeneProductBID (HGNC)
BIRC2GeneProductBIRC2 (HGNC)
BIRC3GeneProductBIRC3 (HGNC)
BIRC5GeneProductBIRC5 (HGNC)
BIRC7GeneProductBIRC7 (HGNC)
BMP2GeneProductBMP2 (HGNC)
BMP4GeneProductBMP4 (HGNC)
BRAFGeneProductBRAF (HGNC)
BRCA2GeneProductBRCA2 (HGNC)
CALML1GeneProductCALML1 (HGNC)
CALML2GeneProductCALML2 (HGNC)
CALML3GeneProductCALML3 (HGNC)
CALML4GeneProductCALML4 (HGNC)
CALML5GeneProductCALML5 (HGNC)
CALML6GeneProductCALML6 (HGNC)
CAMK2AGeneProductCAMK2A (HGNC)
CAMK2BGeneProductCAMK2B (HGNC)
CAMK2DGeneProductCAMK2D (HGNC)
CAMK2GGeneProductCAMK2G (HGNC)
CASP3GeneProductCASP3 (HGNC)
CASP7GeneProductCASP7 (HGNC)
CASP8GeneProductCASP8 (HGNC)
CASP9GeneProductCASP9 (HGNC)
CBLGeneProductCBL (HGNC)
CCDC42GeneProductCCDC42 (HGNC)
CCDC6GeneProductCCDC6 (HGNC)
CCNA1GeneProductCCNA1 (HGNC)
CCNA2GeneProductCCNA2 (HGNC)
CCND1GeneProductCCND1 (HGNC)
CCND2GeneProductCCND2 (HGNC)
CCND3GeneProductCCND3 (HGNC)
CCNE1GeneProductCCNE1 (HGNC)
CCNE2GeneProductCCNE2 (HGNC)
CDH1GeneProductCDH1 (HGNC)
CDK2GeneProductCDK2 (HGNC)
CDK4GeneProductCDK4 (HGNC)
CDK6GeneProductCDK6 (HGNC)
CDKN1AGeneProductCDKN1A (HGNC)
CDKN1BGeneProductCDKN1B (HGNC)
CDKN2AGeneProductCDKN2A (HGNC)
CDKN2BGeneProductCDKN2B (HGNC)
CEBPAGeneProductCEBPA (HGNC)
CHUKGeneProductCHUK (HGNC)
CKS1BGeneProductCKS1B (HGNC)
CREBBPGeneProductCREBBP (HGNC)
CRKGeneProductCRK (HGNC)
CRKLGeneProductCRKL (HGNC)
CSF1RGeneProductCSF1R (HGNC)
CSF2RAGeneProductCSF2RA (HGNC)
CSF3RGeneProductCSF3R (HGNC)
CTBP1GeneProductCTBP1 (HGNC)
CTBP2GeneProductCTBP2 (HGNC)
CTNNA1GeneProductCTNNA1 (HGNC)
CTNNA2GeneProductCTNNA2 (HGNC)
CTNNA3GeneProductCTNNA3 (HGNC)
CTNNB1GeneProductCTNNB1 (HGNC)
CUL1GeneProductCUL1 (HGNC)
CUL2GeneProductCUL2 (HGNC)
CXCL12GeneProductCXCL12 (HGNC)
CXCL8GeneProductCXCL8 (HGNC)
CXCR4GeneProductCXCR4 (HGNC)
CYCSGeneProductCYCS (HGNC)
Ca2+MetaboliteCHEBI:29108 (ChEBI)
Calcium signaling pathwayPathway
Cell cyclePathwayWP179 (WikiPathways)
CholesterolMetaboliteHMDB00067 (HMDB)
CortisolMetaboliteHMDB00063 (HMDB)
CortisoneMetaboliteHMDB02802 (HMDB)
DAGMetaboliteC00165 (KEGG Compound)
DAPK1GeneProductDAPK1 (HGNC)
DAPK2GeneProductDAPK2 (HGNC)
DAPK3GeneProductDAPK3 (HGNC)
DCCGeneProductDCC (HGNC)
DDB2GeneProductDDB2 (HGNC)
DLL1GeneProductDLL1 (HGNC)
DLL3GeneProductDLL3 (HGNC)
DLL4GeneProductDLL4 (HGNC)
DNAMetaboliteCHEBI:16991 (ChEBI)
DVL1GeneProductDVL1 (HGNC)
DVL2GeneProductDVL2 (HGNC)
DVL3GeneProductDVL3 (HGNC)
DehydroepiandrosteroneMetaboliteHMDB00077 (HMDB)
DihydrotestosteroneMetaboliteHMDB02961 (HMDB)
E2F1GeneProductE2F1 (HGNC)
E2F2GeneProductE2F2 (HGNC)
E2F3GeneProductE2F3 (HGNC)
EDN1GeneProductEDN1 (HGNC)
EDNRAGeneProductEDNRA (HGNC)
EDNRBGeneProductEDNRB (HGNC)
EGFGeneProductEGF (HGNC)
EGFRGeneProductEGFR (HGNC)
EGLN1GeneProductEGLN1 (HGNC)
EGLN2GeneProductEGLN2 (HGNC)
EGLN3GeneProductEGLN3 (HGNC)
ELK1GeneProductELK1 (HGNC)
ELOBGeneProductELOB (HGNC)
ELOCGeneProductELOC (HGNC)
EML4GeneProductEML4 (HGNC)
EP300GeneProductEP300 (HGNC)
EPAS1GeneProductEPAS1 (HGNC)
ERBB2GeneProductERBB2 (HGNC)
ESR1GeneProductESR1 (HGNC)
ESR2GeneProductESR2 (HGNC)
ETS1GeneProductETS1 (HGNC)
EstradiolMetaboliteHMDB00151 (HMDB)
Estrogen signaling pathwayPathwayWP712 (WikiPathways)
F2GeneProductF2 (HGNC)
F2RGeneProductF2R (HGNC)
F2RL3GeneProductF2RL3 (HGNC)
FADDGeneProductFADD (HGNC)
FASGeneProductFAS (HGNC)
FASLGGeneProductFASLG (HGNC)
FGF1GeneProductFGF1 (HGNC)
FGFR1GeneProductFGFR1 (HGNC)
FGFR2GeneProductFGFR2 (HGNC)
FGFR3GeneProductFGFR3 (HGNC)
FGFR4GeneProductFGFR4 (HGNC)
FHGeneProductFH (HGNC)
FLT3GeneProductFLT3 (HGNC)
FLT3LGGeneProductFLT3LG (HGNC)
FLT4GeneProductFLT4 (HGNC)
FOSGeneProductFOS (HGNC)
FOXO1GeneProductFOXO1 (HGNC)
FRAT1GeneProductFRAT1 (HGNC)
FRAT2GeneProductFRAT2 (HGNC)
FlutamideMetaboliteHMDB14642 (HMDB)
Focal adhesionPathwayWP306 (WikiPathways)
GADD45AGeneProductGADD45A (HGNC)
GADD45BGeneProductGADD45B (HGNC)
GADD45GGeneProductGADD45G (HGNC)
GLI1GeneProductGLI1 (HGNC)
GLI2GeneProductGLI2 (HGNC)
GLI3GeneProductGLI3 (HGNC)
GNA11GeneProductGNA11 (HGNC)
GNA12GeneProductGNA12 (HGNC)
GNA13GeneProductGNA13 (HGNC)
GNAI1GeneProductGNAI1 (HGNC)
GNAI2GeneProductGNAI2 (HGNC)
GNAI3GeneProductGNAI3 (HGNC)
GNAQGeneProductGNAQ (HGNC)
GNASGeneProductGNAS (HGNC)
GNB1GeneProductGNB1 (HGNC)
GNB2GeneProductGNB2 (HGNC)
GNB3GeneProductGNB3 (HGNC)
GNB4GeneProductGNB4 (HGNC)
GNB5GeneProductGNB5 (HGNC)
GNG10GeneProductGNG10 (HGNC)
GNG11GeneProductGNG11 (HGNC)
GNG12GeneProductGNG12 (HGNC)
GNG13GeneProductGNG13 (HGNC)
GNG2GeneProductGNG2 (HGNC)
GNG3GeneProductGNG3 (HGNC)
GNG4GeneProductGNG4 (HGNC)
GNG5GeneProductENSG00000174021 (Ensembl)
GNG7GeneProductGNG7 (HGNC)
GNG8GeneProductGNG8 (HGNC)
GNGT1GeneProductGNGT1 (HGNC)
GNGT2GeneProductGNGT2 (HGNC)
GRB2GeneProductGRB2 (HGNC)
GSK3BGeneProductGSK3B (HGNC)
GSTP1GeneProductGSTP1 (HGNC)
HDAC1GeneProductHDAC1 (HGNC)
HDAC2GeneProductHDAC2 (HGNC)
HES1GeneProductHES1 (HGNC)
HES5GeneProductHES5 (HGNC)
HEY1GeneProductHEY1 (HGNC)
HEY2GeneProductHEY2 (HGNC)
HEYLGeneProductHEYL (HGNC)
HGFGeneProductHGF (HGNC)
HHIPGeneProductHHIP (HGNC)
HIF-1 signaling pathwayPathway
HIF1AGeneProductHIF1A (HGNC)
HMOX1GeneProductHMOX1 (HGNC)
HRASGeneProductHRAS (HGNC)
HSP90AA1GeneProductHSP90AA1 (HGNC)
HSP90AB1GeneProductHSP90AB1 (HGNC)
HSP90B1GeneProductHSP90B1 (HGNC)
Hedgehog signaling pathwayPathwayWP4249 (WikiPathways)
Hydrogen peroxideMetaboliteHMDB03125 (HMDB)
Hydroperoxyl radicalMetaboliteC21641 (ChEMBL compound)
Hydroxyl radicalMetaboliteC16844 (KEGG Compound)
IGF1GeneProductIGF1 (HGNC)
IGF1RGeneProductIGF1R (HGNC)
IGF2GeneProductIGF2 (HGNC)
IKBKBGeneProductIKBKB (HGNC)
IKBKGGeneProductIKBKG (HGNC)
IL6GeneProductIL6 (HGNC)
IP3MetaboliteC01245 (KEGG Compound)
ITGA2BGeneProductITGA2B (HGNC)
ITGA2GeneProductITGA2 (HGNC)
ITGA3GeneProductITGA3 (HGNC)
ITGA6GeneProductITGA6 (HGNC)
ITGAVGeneProductITGAV (HGNC)
ITGB1GeneProductITGB1 (HGNC)
JAG1GeneProductJAG1 (HGNC)
JAG2GeneProductJAG2 (HGNC)
JAK1GeneProductJAK1 (HGNC)
JAK2GeneProductJAK2 (HGNC)
JAK3GeneProductJAK3 (HGNC)
JUNGeneProductJUN (HGNC)
JUPGeneProductJUP (HGNC)
Jak-STAT signaling pathwayPathway
KEAP1GeneProductKEAP1 (HGNC)
KIF7GeneProductKIF7 (HGNC)
KITGeneProductKIT (HGNC)
KITLGGeneProductKITLG (HGNC)
KLK3GeneProductKLK3 (HGNC)
KNG1GeneProductKNG1 (HGNC)
KRASGeneProductKRAS (HGNC)
LEF1GeneProductLEF1 (HGNC)
LPAR1GeneProductLPAR1 (HGNC)
LPAR2GeneProductLPAR2 (HGNC)
LPAR3GeneProductLPAR3 (HGNC)
LPAR4GeneProductLPAR4 (HGNC)
LPAR5GeneProductLPAR5 (HGNC)
LPAR6GeneProductLPAR6 (HGNC)
LRP5GeneProductLRP5 (HGNC)
LRP6GeneProductLRP6 (HGNC)
MAP2K1GeneProductMAP2K1 (HGNC)
MAP2K2GeneProductMAP2K2 (HGNC)
MAPK signaling pathwayPathwayWP382 (WikiPathways)
MAPK10GeneProductMAPK10 (HGNC)
MAPK1GeneProductMAPK1 (HGNC)
MAPK3GeneProductMAPK3 (HGNC)
MAPK8GeneProductMAPK8 (HGNC)
MAPK9GeneProductMAPK9 (HGNC)
MAXGeneProductMAX (HGNC)
MDM2GeneProductMDM2 (HGNC)
MECOMGeneProductMECOM (HGNC)
METGeneProductMET (HGNC)
MITFGeneProductMITF (HGNC)
MLH1GeneProductMLH1 (HGNC)
MMP1GeneProductMMP1 (HGNC)
MMP2GeneProductMMP2 (HGNC)
MMP3GeneProductMMP3 (HGNC)
MSH2GeneProductMSH2 (HGNC)
MSH3GeneProductMSH3 (HGNC)
MSH6GeneProductMSH6 (HGNC)
MST1GeneProductMST1 (HGNC)
MTORGeneProductMTOR (HGNC)
MYCGeneProductMYC (HGNC)
MalateMetaboliteCHEBI:30797 (ChEBI)
NCOA1GeneProductNCOA1 (HGNC)
NCOA3GeneProductNCOA3 (HGNC)
NCOA4GeneProductNCOA4 (HGNC)
NFE2L2GeneProductNFE2L2 (HGNC)
NFKB1GeneProductNFKB1 (HGNC)
NFKB2GeneProductNFKB2 (HGNC)
NFKBIAGeneProductNFKBIA (HGNC)
NKX3-1GeneProductNKX3-1 (HGNC)
NOS2GeneProductNOS2 (HGNC)
NOTCH1GeneProductNOTCH1 (HGNC)
NOTCH2GeneProductNOTCH2 (HGNC)
NOTCH3GeneProductNOTCH3 (HGNC)
NOTCH4GeneProductNOTCH4 (HGNC)
NQO1GeneProductNQO1 (HGNC)
NRASGeneProductNRAS (HGNC)
NTRK1GeneProductNTRK1 (HGNC)
Nitric oxideMetaboliteHMDB03378 (HMDB)
Notch signaling pathwayPathwayWP268 (WikiPathways)
PAMetaboliteC00416 (KEGG Compound)
PAX8GeneProductPAX8 (HGNC)
PDGFAGeneProductPDGFA (HGNC)
PDGFBGeneProductPDGFB (HGNC)
PDGFRAGeneProductPDGFRA (HGNC)
PDGFRBGeneProductPDGFRB (HGNC)
PGE2MetaboliteHMDB01220 (HMDB)
PGFGeneProductPGF (HGNC)
PI3K-Akt signaling pathwayPathwayWP4172 (KEGG Pathway)
PIK3CAGeneProductPIK3CA (HGNC)
PIK3CBGeneProductPIK3CB (HGNC)
PIK3CDGeneProductPIK3CD (HGNC)
PIK3R1GeneProductPIK3R1 (HGNC)
PIK3R2GeneProductPIK3R2 (HGNC)
PIK3R3GeneProductPIK3R3 (HGNC)
PIM1GeneProductPIM1 (HGNC)
PIM2GeneProductPIM2 (HGNC)
PIP3MetaboliteC05981 (KEGG Compound)
PLCB1GeneProductPLCB1 (HGNC)
PLCB2GeneProductPLCB2 (HGNC)
PLCB3GeneProductPLCB3 (HGNC)
PLCB4GeneProductPLCB4 (HGNC)
PLCG1GeneProductPLCG1 (HGNC)
PLCG2GeneProductPLCG2 (HGNC)
PLD1GeneProductPLD1 (HGNC)
PLD2GeneProductPLD2 (HGNC)
PLEKHG5GeneProductPLEKHG5 (HGNC)
PMAIP1GeneProductPMAIP1 (HGNC)
PMLGeneProductPML (HGNC)
POLKGeneProductPOLK (HGNC)
PPAR signaling pathwayPathwayWP3942 (WikiPathways)
PPARDGeneProductPPARD (HGNC)
PPARGGeneProductPPARG (HGNC)
PRKACAGeneProductPRKACA (HGNC)
PRKACBGeneProductPRKACB (HGNC)
PRKACGGeneProductPRKACG (HGNC)
PRKCAGeneProductPRKCA (HGNC)
PRKCBGeneProductPRKCB (HGNC)
PRKCGGeneProductPRKCG (HGNC)
PTCH1GeneProductPTCH1 (HGNC)
PTCH2GeneProductPTCH2 (HGNC)
PTENGeneProductPTEN (HGNC)
PTGER1GeneProductPTGER1 (HGNC)
PTGER2GeneProductPTGER2 (HGNC)
PTGER3GeneProductPTGER3 (HGNC)
PTGER4GeneProductPTGER4 (HGNC)
PTGS2GeneProductPTGS2 (HGNC)
PTK2GeneProductPTK2 (HGNC)
ProgesteroneMetaboliteHMDB01830 (HMDB)
RAC1GeneProductRAC1 (HGNC)
RAC2GeneProduct5880 (Entrez Gene)
RAC3GeneProductRAC3 (HGNC)
RAD51GeneProductRAD51 (HGNC)
RAF1GeneProductRAF1 (HGNC)
RALAGeneProductRALA (HGNC)
RALBP1GeneProductRALBP1 (HGNC)
RALBGeneProductRALB (HGNC)
RALGDSGeneProductRALGDS (HGNC)
RARAGeneProductRARA (HGNC)
RARBGeneProductRARB (HGNC)
RASGRP1GeneProductRASGRP1 (HGNC)
RASGRP2GeneProductRASGRP2 (HGNC)
RASGRP3GeneProductRASGRP3 (HGNC)
RASGRP4GeneProductRASGRP4 (HGNC)
RASSF1GeneProductRASSF1 (HGNC)
RASSF5GeneProductRASSF5 (HGNC)
RB1GeneProductRB1 (HGNC)
RBX1GeneProductRBX1 (HGNC)
RELAGeneProductRELA (HGNC)
RETGeneProductRET (HGNC)
RHOAGeneProductRHOA (HGNC)
ROCK1GeneProductROCK1 (HGNC)
ROCK2GeneProductROCK2 (HGNC)
RPS6KA5GeneProductRPS6KA5 (HGNC)
RPS6KB1GeneProductRPS6KB1 (HGNC)
RPS6KB2GeneProductRPS6KB2 (HGNC)
RUNX1GeneProductRUNX1 (HGNC)
RUNX1T1GeneProductRUNX1T1 (HGNC)
RXRAGeneProductRXRA (HGNC)
RXRBGeneProductRXRB (HGNC)
RXRGGeneProductRXRG (HGNC)
Retinoic AcidMetaboliteCHEBI:15367 (ChEBI)
SHHGeneProductSHH (HGNC)
SKP1GeneProductSKP1 (HGNC)
SKP2GeneProductSKP2 (HGNC)
SLC2A1GeneProductSLC2A1 (HGNC)
SMAD2GeneProductSMAD2 (HGNC)
SMAD3GeneProductSMAD3 (HGNC)
SMAD4GeneProductSMAD4 (HGNC)
SMOGeneProductSMO (HGNC)
SOS1GeneProductSOS1 (HGNC)
SOS2GeneProductSOS2 (HGNC)
SP1GeneProductENSG00000185591 (Ensembl)
SPI1GeneProductSPI1 (HGNC)
STAT1GeneProductSTAT1 (HGNC)
STAT2GeneProductSTAT2 (HGNC)
STAT3GeneProductSTAT3 (HGNC)
STAT4GeneProductSTAT4 (HGNC)
STAT5AGeneProductSTAT5A (HGNC)
STAT5BGeneProductSTAT5B (HGNC)
STAT6GeneProductSTAT6 (HGNC)
SUFUGeneProductSUFU (HGNC)
SuperoxideMetaboliteHMDB02168 (HMDB)
TCF7L1GeneProductTCF7L1 (HGNC)
TCF7L2GeneProductTCF7L2 (HGNC)
TCF7GeneProductTCF7 (HGNC)
TERCGeneProductTERC (HGNC)
TERTGeneProductTERT (HGNC)
TFGGeneProductTFG (HGNC)
TGF-beta signaling pathwayPathwayWP560 (WikiPathways)
TGFAGeneProductTGFA (HGNC)
TGFB1GeneProductTGFB1 (HGNC)
TGFB2GeneProductTGFB2 (HGNC)
TGFB3GeneProductTGFB3 (HGNC)
TGFBR1GeneProductTGFBR1 (HGNC)
TGFBR2GeneProductTGFBR2 (HGNC)
TP53GeneProductTP53 (HGNC)
TPM3GeneProductTPM3 (HGNC)
TPRGeneProductTPR (HGNC)
TRAF1GeneProductTRAF1 (HGNC)
TRAF2GeneProductTRAF2 (HGNC)
TRAF3GeneProductTRAF3 (HGNC)
TRAF4GeneProductTRAF4 (HGNC)
TRAF5GeneProductTRAF5 (HGNC)
TRAF6GeneProductTRAF6 (HGNC)
TXNRD1GeneProductTXNRD1 (HGNC)
TXNRD2GeneProductTXNRD2 (HGNC)
TXNRD3GeneProductTXNRD3 (HGNC)
TestosteroneMetaboliteHMDB00234 (HMDB)
VEGF signaling pathwayPathwayWP3888 (WikiPathways)
VEGFAGeneProductVEGFA (HGNC)
VEGFBGeneProductVEGFB (HGNC)
VEGFCGeneProductVEGFC (HGNC)
VEGFDGeneProductVEGFD (HGNC)
VHLGeneProductVHL (HGNC)
Wnt signaling pathwayPathwayWP428 (WikiPathways)
XIAPGeneProductXIAP (HGNC)
ZBTB16GeneProductZBTB16 (HGNC)
ZBTB17GeneProductZBTB17 (HGNC)
cAMP signaling pathwayPathway
cAMPMetaboliteCHEBI:17489 (ChEBI)
fumarateMetaboliteCHEBI:29806 (ChEBI)
mTOR signaling pathwayPathwayWP3932 (WikiPathways)
p53 signaling pathwayPathway

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP5434"
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