Regulation of actin cytoskeleton (Canis familiaris)

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RTKGrowth Factor (GF)stress fiberGPCRActomyosinassembly contractionStabilizationof actinFilipodiaLamellipodiaGPCRFocal adhesionassemblyActin polymerizationActin polymerization-pFocal complexassemblyChemotactic factorRAS+pPI3KChemotatic factorRAS?Gene ExpressionActin polymerizationstress fiberPI3KRTKGFFGF9PAK2Focal AdhesionpathwayCHRM2FGF15RAC1P4SOS2LOC100686332BDKRB2FGFR2PFN1MAPK3F2RKRASPIP3PFN1FGF1FGF13SSH2FGF12PIK3C2BRRASFGF7LPSVAV1VCLBCAR1CHRM4PIK3R1DOCK1PIK3C2AFGF23FGF6MAPK SignalingpathwayFGF18PIK3CDBAIAP2MAP2K2Adherens junctionpathwayPIK3CAPDGFBMYH10FGFR3ARPC5BRAFPIK3CBRDXINS1PDGFACFL1Apc2RHOAPDGFRAARHGEF4AcetylcholineARHGEF7Focal AdhesionpathwayLOC442775LOC442937RRAS2FGF4ARHGEF6FGF3RAF1ITGA1BDKRB1PAK7GNA12SOS1PDGFRBMAPK6ACTN1INS2FGF21VCLLOC100856038EGFRROCK1PPP1R12AACTBPIK3R5LOC100856339FGFR4PIP4K2CPIP5K1ANCKAP1FGF16FGF8CDC42LOC607701FGF11NRASVIL1MRASLOC442937PIK3C2GLOC100856539ROCK2PIK3R4FGF5FN1CYFIP2FGF17MAPK1DIAP3LIMK1RAC2MYLKARHGEF1PAK4ABI2LOC612404PAK1WASMYL1FGD1EZRSSH3PTK2CFL2CHRM1BAIAP2BradykininMYL3CHRM5PIK3R2C11orf13LOC442937PIP5K1CPIP2ACTBMSNWASF2CD14RAC3IQGAP1RAC1PIP4K2APIP4K2BFGF20WASF1GIT1EGFPIK3C3PAK3CSKARHGAP35PIP4K2AMOSSLC9A1MAP2K1FGF2APCPIP5K1BMAPK4PXNARPC5ACTBFGF10GNA13FGF14TMSB4XPIP5KL1SSH1GSNPIK3CGCHRM3LOC100856477DIAP1CRKLOC490390PIP2ARHGEF6


Description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP51(r45278) with a 89% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
128552view04:35, 12 February 2024EweitzModified title
72086view21:21, 24 October 2013Mkutmonadded datasource to "Focal Adhesion pathway" and "MAPK Signaling pathway"
71469view19:17, 17 October 2013MaintBotAutomated update of data sources
68550view22:35, 5 July 2013MaintBotUpdated to 2013 gpml schema
48152view18:46, 9 May 2012MaintBotUpdating from human to fix xrefs
40707view21:51, 1 March 2011MaintBotRemoved redundant pathway information and comments
33987view18:33, 9 December 2009MaintBotAutomatic update of empty xrefs
32262view13:01, 15 August 2009MaintBotFixed text labels
31789view12:14, 14 August 2009MaintBotFixed group labels
31289view20:06, 13 August 2009MaintBotFixed text labels
30747view23:06, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ABI2GeneProduct488485 (Entrez Gene)
ACTBGeneProduct403580 (Entrez Gene)
ACTN1GeneProduct480369 (Entrez Gene)
APCGeneProduct479139 (Entrez Gene)
ARHGAP35GeneProduct403543 (Entrez Gene)
ARHGEF1GeneProduct
ARHGEF4GeneProduct483856 (Entrez Gene)
ARHGEF6GeneProduct610290 (Entrez Gene)
ARHGEF7GeneProduct485552 (Entrez Gene)
ARPC5GeneProduct480037 (Entrez Gene)
AcetylcholineMetabolite51-84-3 (CAS)
Adherens junction pathwayPathway
Apc2GeneProduct
BAIAP2GeneProduct403473 (Entrez Gene)
BCAR1GeneProduct479648 (Entrez Gene)
BDKRB1GeneProduct490847 (Entrez Gene)
BDKRB2GeneProduct403658 (Entrez Gene)
BRAFGeneProduct475526 (Entrez Gene)
BradykininMetabolite58-82-2 (CAS)
C11orf13GeneProduct
CD14GeneProduct607076 (Entrez Gene)
CDC42GeneProduct403934 (Entrez Gene)
CFL1GeneProduct476022 (Entrez Gene)
CFL2GeneProduct490649 (Entrez Gene)
CHRM1GeneProduct483776 (Entrez Gene)
CHRM2GeneProduct403858 (Entrez Gene)
CHRM3GeneProduct403827 (Entrez Gene)
CHRM4GeneProduct611314 (Entrez Gene)
CHRM5GeneProduct487472 (Entrez Gene)
CRKGeneProduct100684309 (Entrez Gene)
CSKGeneProduct487649 (Entrez Gene)
CYFIP2GeneProduct479317 (Entrez Gene)
DIAP1GeneProduct
DIAP3GeneProduct
DOCK1GeneProduct486934 (Entrez Gene)
EGFGeneProduct403657 (Entrez Gene)
EGFRGeneProduct404306 (Entrez Gene)
EZRGeneProduct484056 (Entrez Gene)
F2RGeneProduct488942 (Entrez Gene)
FGD1GeneProduct491901 (Entrez Gene)
FGF10GeneProduct612454 (Entrez Gene)
FGF11GeneProduct607829 (Entrez Gene)
FGF12GeneProduct478676 (Entrez Gene)
FGF13GeneProduct492174 (Entrez Gene)
FGF14GeneProduct485537 (Entrez Gene)
FGF15GeneProduct
FGF1GeneProduct607724 (Entrez Gene)
FGF16GeneProduct491974 (Entrez Gene)
FGF17GeneProduct607952 (Entrez Gene)
FGF18GeneProduct611641 (Entrez Gene)
FGF20GeneProduct
FGF21GeneProduct484395 (Entrez Gene)
FGF23GeneProduct611773 (Entrez Gene)
FGF2GeneProduct403857 (Entrez Gene)
FGF3GeneProduct
FGF4GeneProduct483680 (Entrez Gene)
FGF5GeneProduct608459 (Entrez Gene)
FGF6GeneProduct486735 (Entrez Gene)
FGF7GeneProduct403915 (Entrez Gene)
FGF8GeneProduct403868 (Entrez Gene)
FGF9GeneProduct477340 (Entrez Gene)
FGFR2GeneProduct415125 (Entrez Gene)
FGFR3GeneProduct488808 (Entrez Gene)
FGFR4GeneProduct489095 (Entrez Gene)
FN1GeneProduct403845 (Entrez Gene)
Focal Adhesion pathwayPathwayWP306 (WikiPathways)
GIT1GeneProduct491180 (Entrez Gene)
GNA12GeneProduct
GNA13GeneProduct490901 (Entrez Gene)
GSNGeneProduct474819 (Entrez Gene)
INS1GeneProduct
INS2GeneProduct
IQGAP1GeneProduct479050 (Entrez Gene)
ITGA1GeneProduct489210 (Entrez Gene)
KRASGeneProduct403871 (Entrez Gene)
LIMK1GeneProduct489800 (Entrez Gene)
LOC100686332GeneProduct100686332 (Entrez Gene)
LOC100856038GeneProduct100856038 (Entrez Gene)
LOC100856339GeneProduct100856339 (Entrez Gene)
LOC100856477GeneProduct100856477 (Entrez Gene)
LOC100856539GeneProduct100856539 (Entrez Gene)
LOC442775GeneProduct
LOC442937GeneProduct442937 (Entrez Gene)
LOC490390GeneProduct490390 (Entrez Gene)
LOC607701GeneProduct607701 (Entrez Gene)
LOC612404GeneProduct612404 (Entrez Gene)
LPSMetaboliteC00338 (KEGG Compound)
MAP2K1GeneProduct478347 (Entrez Gene)
MAP2K2GeneProduct611939 (Entrez Gene)
MAPK Signaling pathwayPathwayWP382 (WikiPathways)
MAPK1GeneProduct477575 (Entrez Gene)
MAPK3GeneProduct479790 (Entrez Gene)
MAPK4GeneProduct491690 (Entrez Gene)
MAPK6GeneProduct478311 (Entrez Gene)
MOSGeneProduct486959 (Entrez Gene)
MRASGeneProduct477082 (Entrez Gene)
MSNGeneProduct491924 (Entrez Gene)
MYH10GeneProduct479497 (Entrez Gene)
MYL1GeneProduct478896 (Entrez Gene)
MYL3GeneProduct476644 (Entrez Gene)
MYLKGeneProduct488012 (Entrez Gene)
NCKAP1GeneProduct478828 (Entrez Gene)
NRASGeneProduct403872 (Entrez Gene)
PAK1GeneProduct607885 (Entrez Gene)
PAK2GeneProduct612814 (Entrez Gene)
PAK3GeneProduct492067 (Entrez Gene)
PAK4GeneProduct484513 (Entrez Gene)
PAK7GeneProduct485772 (Entrez Gene)
PDGFAGeneProduct491597 (Entrez Gene)
PDGFBGeneProduct442986 (Entrez Gene)
PDGFRAGeneProduct442860 (Entrez Gene)
PDGFRBGeneProduct442985 (Entrez Gene)
PFN1GeneProduct
PIK3C2AGeneProduct485399 (Entrez Gene)
PIK3C2BGeneProduct478938 (Entrez Gene)
PIK3C2GGeneProduct477681 (Entrez Gene)
PIK3C3GeneProduct490477 (Entrez Gene)
PIK3CAGeneProduct488084 (Entrez Gene)
PIK3CBGeneProduct477085 (Entrez Gene)
PIK3CDGeneProduct489644 (Entrez Gene)
PIK3CGGeneProduct483266 (Entrez Gene)
PIK3R1GeneProduct487235 (Entrez Gene)
PIK3R2GeneProduct609956 (Entrez Gene)
PIK3R4GeneProduct477064 (Entrez Gene)
PIK3R5GeneProduct612805 (Entrez Gene)
PIP2MetaboliteC04637 (KEGG Compound)
PIP3MetaboliteC05981 (KEGG Compound)
PIP4K2AGeneProduct608414 (Entrez Gene)
PIP4K2BGeneProduct491034 (Entrez Gene)
PIP4K2CGeneProduct474417 (Entrez Gene)
PIP5K1AGeneProduct475846 (Entrez Gene)
PIP5K1BGeneProduct476331 (Entrez Gene)
PIP5K1CGeneProduct485054 (Entrez Gene)
PIP5KL1GeneProduct609122 (Entrez Gene)
PPP1R12AGeneProduct475411 (Entrez Gene)
PTK2GeneProduct475108 (Entrez Gene)
PXNGeneProduct486299 (Entrez Gene)
RAC1GeneProduct403955 (Entrez Gene)
RAC1P4GeneProduct
RAC2GeneProduct481271 (Entrez Gene)
RAC3GeneProduct
RAF1GeneProduct484648 (Entrez Gene)
RDXGeneProduct479446 (Entrez Gene)
RHOAGeneProduct403954 (Entrez Gene)
ROCK1GeneProduct480181 (Entrez Gene)
ROCK2GeneProduct482970 (Entrez Gene)
RRAS2GeneProduct476865 (Entrez Gene)
RRASGeneProduct476413 (Entrez Gene)
SLC9A1GeneProduct478171 (Entrez Gene)
SOS1GeneProduct483042 (Entrez Gene)
SOS2GeneProduct490682 (Entrez Gene)
SSH1GeneProduct477526 (Entrez Gene)
SSH2GeneProduct491183 (Entrez Gene)
SSH3GeneProduct483699 (Entrez Gene)
TMSB4XGeneProduct
VAV1GeneProduct485016 (Entrez Gene)
VCLGeneProduct479252 (Entrez Gene)
VIL1GeneProduct488522 (Entrez Gene)
WASGeneProduct491867 (Entrez Gene)
WASF1GeneProduct475024 (Entrez Gene)
WASF2GeneProduct487343 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1178"
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