TCA cycle (Danio rerio)

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CytosolDegradation of fatty acidscontaining an even number of carbonsElectron transport chainMitochondrionDegradation of fatty acidscontaining an odd number of carbonsAcetyl-CoAmdh1aaogdhaSuccinateL-malateFumaratezgc:165532aco2idh3adlatsdhdafhpcxbsdhaPyruvatesdhbdldhidh3bpdk4sucla2OxaloacetateCitratesuclg2dlstpdk3bGluconeogenesisdldhsdhcFatty acid synthesisIsocitrateAlpha-ketoglutaratePDHA2mdh2idh2pdk2bpdp2L-malatesuclg1OxaloacetateSuccinyl-CoApdhxcspdha1apdk1pdhbsdhdbmdh1abmdh1bpdha1bidh3bGlycolysis


Description

Tricarboxylic acid (TCA) cycle in zebrafish. Also known as the Krebs cycle, this pathway releases energy stored in nutrients through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins.

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Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
128709view22:18, 20 February 2024EgonwFixed a few datasources and made one interaction a mim-translation
127978view21:21, 20 January 2024EweitzModified description
127977view21:17, 20 January 2024EweitzRefine node size, consolidate text containers, fix case
127976view21:11, 20 January 2024EweitzIncrease font size: 10 -> 12
127975view21:08, 20 January 2024EweitzUse proper zebrafish gene names, standard on Ensembl IDs
127974view20:41, 20 January 2024EweitzUpdate metabolite node color to standard blue
127973view20:34, 20 January 2024EweitzUse proper zebrafish gene names, standardize to Ensembl IDs
127972view20:07, 20 January 2024EweitzRefine pathway representations, change low-contrast neon green to more visible orange
127971view19:57, 20 January 2024EweitzStandardize case
125413view06:32, 13 February 2023EgonwRemoved outdated 'last modified'
119952view11:08, 29 September 2021DdiglesChanged caffeine citrate back to citrate.
116911view11:48, 15 May 2021EweitzModified title
96499view06:47, 16 March 2018EgonwReplaced a secondary ChEBI identifier with a primary identifier.
96474view15:57, 15 March 2018SusanAnnotated metabolites
96468view15:48, 15 March 2018SusanConnected lines
91937view10:56, 6 April 2017LWackersAdded alpha and beta subunits of some genes, added annotations.
77409view22:42, 5 September 2014MaintBotremoved homology mapp label
71527view19:22, 17 October 2013MaintBotAutomated update of data sources
68660view05:17, 6 July 2013MaintBotUpdated to 2013 gpml schema
67684view11:49, 26 June 2013DdiglesOntology Term : 'citrate cycle pathway' added !
53545view21:19, 8 November 2012EgonwReplaced multiple general nodes by Metabolite DataNode's.
40831view22:18, 1 March 2011MaintBotRemoved redundant pathway information and comments
34217view21:33, 9 December 2009MaintBotAutomatic update of empty xrefs
20715view11:29, 14 November 2008MaintBot[[Pathway:Danio rerio:Krebs-TCA Cycle]] moved to [[Pathway:WP19]]: Moved to stable identifier
12044view08:45, 15 May 2008MaintBotAdded to category $category
19499view08:45, 15 May 2008N.FidelmanUploaded new pathway
12042view08:45, 15 May 2008KdahlquistUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Acetyl-CoAMetaboliteCHEBI:15351 (ChEBI)
Alpha-ketoglutarateMetaboliteCHEBI:16810 (ChEBI)
CitrateMetaboliteCHEBI:133748 (ChEBI)
Fatty acid synthesisPathway
FumarateMetaboliteCHEBI:18012 (ChEBI)
GluconeogenesisPathwayWP1356 (WikiPathways)
GlycolysisPathwayWP1356 (WikiPathways)
IsocitrateMetaboliteCHEBI:16087 (ChEBI)
L-malateMetaboliteCHEBI:15589 (ChEBI)
OxaloacetateMetaboliteCHEBI:30744 (ChEBI)
PDHA2GeneProduct
PyruvateMetaboliteCHEBI:15361 (ChEBI)
SuccinateMetaboliteCHEBI:30031 (ChEBI)
Succinyl-CoAMetaboliteCHEBI:15380 (ChEBI)
aco2GeneProduct322670 (Entrez Gene)
csGeneProductENSDARG00000103364 (Ensembl)
dlatGeneProduct324201 (Entrez Gene)
dldhGeneProduct399479 (Entrez Gene)
dldhGeneProductENSDARG00000008785 (Ensembl)
dlstGeneProductENSDARG00000014230 (Ensembl)
fhGeneProductENSDARG00000075132 (Ensembl)
idh2GeneProductENSDARG00000003795 (Ensembl)
idh3aGeneProductENSDARG00000030278 (Ensembl)
idh3bGeneProductENSDARG00000044753 (Ensembl)
mdh1aaGeneProductENSDARG00000017772 (Ensembl)
mdh1abGeneProductENSDARG00000103849 (Ensembl)
mdh1bGeneProductENSDARG00000018008 (Ensembl)
mdh2GeneProductENSDARG00000043371 (Ensembl)
ogdhaGeneProductENSDARG00000034270 (Ensembl)
pcxbGeneProductENSDARG00000051939 (Ensembl)
pdha1aGeneProduct406702 (Entrez Gene)
pdha1bGeneProductENSDARG00000010555 (Ensembl)
pdhbGeneProduct406428 (Entrez Gene)
pdhxGeneProductENSDARG00000051756 (Ensembl)
pdk1GeneProductENSDARG00000013128 (Ensembl)
pdk2bGeneProductENSDARG00000059054 (Ensembl)
pdk3bGeneProductENSDARG00000099791 (Ensembl)
pdk4GeneProductENSDARG00000054848 (Ensembl)
pdp2GeneProductENSDARG00000058571 (Ensembl)
sdhaGeneProductENSDARG00000016721 (Ensembl)
sdhbGeneProductENSDARG00000075768 (Ensembl)
sdhcGeneProductENSDARG00000038608 (Ensembl)
sdhdaGeneProductENSDARG00000055712 (Ensembl)
sdhdbGeneProductENSDARG00000030139 (Ensembl)
sucla2GeneProductENSDARG00000005359 (Ensembl)
suclg1GeneProductENSDARG00000052712 (Ensembl)
suclg2GeneProductENSDARG00000044914 (Ensembl)
zgc:165532GeneProductENSDARG00000016964 (Ensembl)

Annotated Interactions

No annotated interactions

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