GLP-1 in pancreatic islet cells (Homo sapiens)
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Description
Factors in GLP-1 production in pancreatic alpha cells, and the hypothetical function of resulting GLP-1 in pancreatic beta cells. Based on Figure 3 in https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9190119.
Quality Tags
Ontology Terms
Bibliography
- Davis EM, Sandoval DA; ''Glucagon-like peptide-1: Actions and influence on pancreatic hormone function''; Comprehensive Physiology, 2020 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
Diabetes | https://www.wikidata.org/wiki/Q12206 (Wikidata) | ||
Exercise | https://www.wikidata.org/wiki/Q219067 (Wikidata) | ||
GCG | GeneProduct | ENSG00000115263 (Ensembl) | |
GLP-1 | Protein | https://www.wikidata.org/wiki/Q424611 (Other) | |
GLP1R | GeneProduct | ENSG00000112164 (Ensembl) | |
Glucose | Metabolite | 17234 (ChEBI) | |
Hyperglycemia | https://www.wikidata.org/wiki/Q271993 (Wikidata) | ||
IL6 | GeneProduct | ENSG00000136244 (Ensembl) | |
IL6R | GeneProduct | ENSG00000160712 (Ensembl) | |
INS | GeneProduct | ENSG00000254647 (Ensembl) | |
Insulin | Protein | P01308 (Uniprot-TrEMBL) | |
Metabolic stress | http://purl.jp/bio/4/id/200906012910470412 (Other) | ||
Obesity | https://www.wikidata.org/wiki/Q12174 (Wikidata) | ||
Proliferation | https://www.wikidata.org/wiki/Q189101 (Wikidata) | ||
SLC2A1 | GeneProduct | ENSG00000117394 (Ensembl) | |
SLC2A2 | GeneProduct | ENSG00000163581 (Ensembl) | |
Systematic inflammation | https://www.wikidata.org/wiki/Q7663815 (Wikidata) |
Annotated Interactions
No annotated interactions