GLP-1 from intestine and pancreas and role in glucose homeostasis (Homo sapiens)
From WikiPathways
Description
Pathway of how GLP-1 produced in alpha cells in the pancreas may contribute to insulin secretion, in addition to GLP-1 from intestine.
Quality Tags
Ontology Terms
Bibliography
- Davis EM, Sandoval DA; ''Glucagon-like peptide-1: Actions and influence on pancreatic hormone function''; Comprehensive Physiology, 2020 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
Amino acid | Metabolite | 33709 (ChEBI) | |
GCG | GeneProduct | ENSG00000115263 (Ensembl) | |
GLP-1 from intestine | Pathway | ||
GLP-1 | Protein | https://www.wikidata.org/wiki/Q424611 (Other) | |
GLP1R | GeneProduct | ENSG00000112164 (Ensembl) | |
Glucagon | Protein | https://www.wikidata.org/wiki/Q170617 (Other) | |
Glucose | Metabolite | 17234 (ChEBI) | |
INS | GeneProduct | ENSG00000254647 (Ensembl) | |
Insulin | Protein | P01308 (Uniprot-TrEMBL) | |
PCSK1 | GeneProduct | ENSG00000175426 (Ensembl) | |
PCSK2 | GeneProduct | ENSG00000125851 (Ensembl) | |
SLC2A1 | GeneProduct | ENSG00000117394 (Ensembl) |
Annotated Interactions
No annotated interactions