EBV LMP1 signaling (Anopheles gambiae)

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Fix interactions Comment: 7 out of 25 lines are not properly connected. Please help improving this pathway by connecting the ends of interactions to nodes.

Approved version The current version of this pathway was approved for data analysis by Eric Weitz.

Annotate nodes Comment: 17 out of 36 DataNodes have a missing external reference. Check DataNode table at the bottom of the page. Please help improve this pathway by annotating gene, protein and metabolite nodes.

Homology Converted Revision {{{tag_revision}}} of this pathway has been inferred from another species (tagged by Maintenance bot). Expression error: Unrecognised punctuation character "{"

Ontology Terms

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Bibliography

1. Song YJ, Jen KY, Soni V, Kieff E, Cahir-McFarland E; ''IL-1 receptor-associated kinase 1 is critical for latent membrane protein 1-induced p65/RelA serine 536 phosphorylation and NF-kappaB activation.''; Proc Natl Acad Sci U S A, 2006 PubMed Europe PMC Scholia
2. Uemura N, Kajino T, Sanjo H, Sato S, Akira S, Matsumoto K, Ninomiya-Tsuji J; ''TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB.''; J Biol Chem, 2006 PubMed Europe PMC Scholia
3. Battaglia F, Delfino S, Merello E, Puppo M, Piva R, Varesio L, Bosco MC; ''Hypoxia transcriptionally induces macrophage-inflammatory protein-3alpha/CCL-20 in primary human mononuclear phagocytes through nuclear factor (NF)-kappaB.''; J Leukoc Biol, 2008 PubMed Europe PMC Scholia
4. Lee JS, Lee JY, Son JW, Oh JH, Shin DM, Yuk JM, Song CH, Paik TH, Jo EK; ''Expression and regulation of the CC-chemokine ligand 20 during human tuberculosis.''; Scand J Immunol, 2008 PubMed Europe PMC Scholia

History

External references

DataNodes

Name	Type	Database reference	Comment
AgaP_AGAP006958	GeneProduct	1270128 (Entrez Gene)
CCL20	GeneProduct
CCL5	GeneProduct
I-Kappa-B	GeneProduct
IFNB	GeneProduct
IKK-alpha	GeneProduct
IKK-alpha	GeneProduct	AGAP009166 (Ensembl)
IKK-beta	GeneProduct	AGAP009166 (Ensembl)
IKK-gamma	GeneProduct	AGAP005933 (Ensembl)
IL8	GeneProduct
JNK	GeneProduct
LMP1	GeneProduct
MAP3K3	GeneProduct
MAP3K7	GeneProduct
NIK	GeneProduct
REL1	GeneProduct	AGAP009515 (Ensembl)
REL2	GeneProduct	AGAP006747 (Ensembl)
SFC complex	GeneProduct
TAB1	GeneProduct
TNF	GeneProduct
TRADD	GeneProduct
TRAF1	GeneProduct
TRAF6	GeneProduct	AGAP003004 (Ensembl)
TUBE	GeneProduct	AGAP003062 (Ensembl)
p38	GeneProduct	AGAP009207 (Ensembl)

Annotated Interactions